Term
Prurigo nodularis-
Hyperkeratotic hyperpigmented nodule arising from repeated picking/scratching, surrounding hypopigmentation |
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2-5mm macaulopapular truncal rash, often from vancomycin, penicillins, cabamazepine, allopurinol. Tx with antihistamines and topical steroids. Also caused by EBV/CMV if given ampicillin or amoxicillin |
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clobetasol
betamethasone dipropionate |
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Definition
high potency topical steroids |
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winter itch- anterior shins old people, porcelin dry cracsk, worse with frequent bathing, soaps. Tx emolliants |
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allergic contact dermatitis, but occuring on eyelids from exposure elswhere |
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treat with low-mid potency topical steroid, compresssion therapy, unna boots |
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involving flexures, pruritis, red, crusted papulovesciular plaques |
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atopic dermatitis diagnosis |
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IgE elevations, eosinophils, history of allergies |
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atopic dermatitis treatment |
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once daily topical steroids; tacrolimus for face and intertriginous areas (wont cause atrophy), emollients |
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widespread localized dissemination of HSV infection |
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palms and sides of fingers - recurrent episodes of tapioca-like itchy vesicles |
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superficial capillaritis causes cayenne-pepper like pigmented patches of skin on extremities, leaving behind permenant hyperpigmentation. Tx with low-potency steroids |
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autoinflammatory condition, pruritic, polygonal papules with surrounding white lines (Wicham striae) associated with liver disease. Tx with topical steroids. |
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ACE-I, thiazides, furosemide, gold, antimalarials, d-penicillamine, b-blockers |
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drop-like lesions, often post-strep, and in children |
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localized pustular psoriasis |
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palmar/soles, often triggered by TNFa inhibitors |
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localized pustular psoriasis |
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calcipotriene/betamethasone, tazarotene, anthralin, phototherapy |
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psoriatic arthritis treatment |
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MTX with etanercept, infliximab, or adalimumab |
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acute recurrent targetoid erythematous mucocutaneous eruption following acute infection or drug, most common HSV |
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erythema multiforme treatment |
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symptomatic, give valtrex to prevent HSV recurrence, can give steroids for symptoms |
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severe cutaneous adverse reactions (SCAR) to drugs |
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Definition
confluent erythema, skin pain, facial edema, fever, LAD, mucosal involvement, hypotension/dyspnea, necrosis--> all bad signs |
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hyperpigmented annular lesions that reoccur repeatedly in same location, etiology tetracyclines, sulfas, flaagyl, barbituates, OCPs |
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dermatomyositis-like eruptions |
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hydroxyurea, statin--> gottron papules, |
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acute febrile neutrophilic dermatosis--> caused by imatinib, OCPs, GCSF, ATRA. Tx with oral steroids |
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subacute cutaneous lupus erythamatosis |
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Definition
caused by HCTZ, CCBs, ACE-I, looks like discrete red papular lesions with scaly plaques |
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Term
AGEP - acute generalized exanthematous pustulosis |
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Definition
acute widespread pustules, fever, leukocytosis, eosinophilia 2/2 b-lactams, fluoroquinolones, antimalarial, sulta, diltiazem. Self-limited |
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Drug reaction with eosinophilia and systemic symptoms- facial edeam, fever, arthralgias, LAD, LFT elevtaions, lymphocytosis, 2/2 anticonvulsants, abacavir, sulfa, allopurinol. Associated with HHV6. |
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Tx with oral steroids, IVIG. Also might get hypothyroidism! |
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papulosquamous eruption with herald patch salmon scaly periphery, then subsequent eruption. Associated with HHV6-7 reactivations. self-limited. can have mild flulike sx. |
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topical retinoids --> benzoyl peroxide --> topical Abx --> if on trunk or severe then add oral Abx --> then isotretinoin |
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must be combined with benzoyl peroxide to prevent resistence |
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require hyerandrogenism to be indicated, takes 5 cycles, give with topicals |
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seterile abscess and sinus tract formation in groin/axillary region, recurrent and painful, treat with topical clindamycin |
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papular eruption around mouth, occuring with inhaled steroids, tx stop steroid, topical antibiotics |
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dermatophytosis treatment |
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given topical antifungal (clotrimazole, miconazole, terbinafine, ciclopirox). NO steroid because may induce deep ifn |
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widespread dermatophyte ifn tx |
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oral itraconazole or griseofulvin. |
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PAS staining of clipping more sensitive than KOH. Must confirm first before treating because 1/2 of cases are nonfungal |
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proximal nailbed onchomycosis |
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Definition
must test for HIV, orals are needed for Tx |
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small light-brown truncal macules on anterior chest caused by malassezia furfur. Tx with selectium lotion or keoconazole shampoo |
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excellent against MRSA but limited spectrum against beta-hemolytic strep, so not first choice for abscess. |
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by culture, otherwise clinda, tetracyclines, rifampin-containing regimens |
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honey-colored crusts, S aureus superficial infection. can treat mild with topical bacitracin and soaking off crusts |
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clindamycin, doxycycline, TMP-SMZ |
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supercifical punched out ulcer with yellow ulcer, strep infection. increased in AIDS/IVDU. Dx oral dicloxacillin and topical mupiricin |
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disseminated cutaneous HSV infection spread by skin breakdown, example in pts with atopic dermatitis |
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cancer causing, forms flat hyperpigmented macules rather than condyloma |
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first line topical salycilic acid, or don't treat. Cryotherapy is only if compliance is a problem |
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along clothing lines, treat with topic steroid, camphor/menthol |
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treat with whole body topical permethrin creatm, repeat 1 week later. itching lasts several weeks after. refractory- ivermectin |
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topical pediculicides. second line- lindane |
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skin biopsy or small wound |
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keep moist with petrolatum, bacitracin does not help, and increases risk of contact dermatitis |
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