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Dermatology
Inflammatory Disorders
49
Medical
Graduate
09/05/2010

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Term
Erythema Nodosum
Definition
Acute inflammatory/immunologic reaction of the panniculus.
Term
Erythema Nodosum
Definition
What infection shows up as deep seated nodules mainly on the pretibial surfaces?
Term
Leukocytoclastic
Definition
- Most common cutaneous form of vasculitis. Involves organs other than the skin, frequently joints, muscles, kidneys. Infiltration of venules by neutrophils with fragmentation of their nuclei.
Term
Henoch-Schonlein Purpura
Definition
Palpable purpura is the hallmark lesion for this skin infection & usually follows another infection. It usually shows up below the beltline.
Term
Polyarteritis Nodosa
Definition
Serious systemic immune complex mediated disorder involving arteries in different organs, sometime the skin. Nodules along the course of superficial arteries
Term
Cutaneous PAN
Definition
Which type of Polyarteritis Nodosa is benign?
Term
Thrombocytopenic Purpura
Definition
Cutaneous hemorrhages occurring in association with a reduced platelet count. Generally with small petechiae, but occasionally with larger ecchymosis.
Term
Meningococcemia
Definition
Neisseria Meningitides seeding from the nasopharynx (carrier rate 5— 15%) which is transmitted person to person through inhalation droplets of aerosolized nasopharyngeal secretions. Purpura (In fulminant cases, purpura, ecchymosis, and confluent, bizarre shaped grayish black necrosis is present.)
Term
Cushings Striae
Definition
 Cutaneous Manifestations - Pink - purple striae present on flanks of abdomen, arms, and thighs. Usually caused by increased gluticosteroids.
Term
Birth weight Change Striae
Definition
Striae present on areas of rapid growth: hips, buttocks, abdomen, and breasts.
Term
Pruritic Urticarial Papules & Plaques of Pregnancy (PUPP)
Definition

Distinct pruritic eruption of pregnancy which begins in the third trimester. Occurs most often in Primigravidae.Pruritis on abdomen, often occurs in striae. 1 -3 mm erythematous papules which quickly coalesce into urticarial plaques. 40% have vesicles in the plaques.

Term
Prurigo Gravidum
Definition
 Common, intense pruritus occurring during the last month of pregnancy.
Term
Herpes Gestationis
Definition
Extremely pruritic eruption. Autoimmune process with circulating complement fixing IgG antibodies.  Papulovesicular disorder with erythematous, edematous papules, urticarial lesions and large tense bulk erosions, and crusts occuring during pregnancy.
Term
Urticaria
Definition
Condition characterized by transient pruritic erythematous swellings of the skin secondary to the release of histamine.
Term
>30 days
Definition
How many days does Urticaria have to be present to be "chronic"?
Term
Dermographism
Definition
Direct pressure on the skin produces urticaria secondary to an exaggerated response of the skin to trauma resulting in histamine release from mast cells. Lesions fade in 30 minutes. The condition ultimately resolves, but it may take years.
Term
Pressure Urticaria
Definition

Generally seen with ordinary urticarial swellings which are more painful and pruritic after prolonged pressure (buttocks or soles of feet).  Lesions may last for hours and recovery is spontaneous.

Term
Physical Urticaria
Definition
Rare condition acquired during adolescence which is self-limiting. Wheals are reproducible using an ice pack, irradiation, or test tube of warm water
Term
Cholinergic Uticaria
Definition
Intensely pruritic erythematous wheals <2 mm in diameter develop as a response to sweating, exercise, or emotion. Thought to be from the release of acetylcholine.
Term
Angioedema
Definition
Same as urticaria except it involves the deep dermis and subcutaneous tissue.
Term
Systemic Lupus Erythematosus
Definition
What disorder is a multisystem disease involving the connective tissue and blood vessels. It affects the hair (scarring alopecia), the mucous membranes,  and the face with a butterfly lesion.
Term
Exfoliative Dermatitis
Definition
 Scaling and erythema over a large area of the body. Generalized or localized exfoliation which may include loss of hair and nails.
Term
Dermatitis Medicamentosa
Definition
Generally abrupt onset of widespread, symmetric erythematous eruption caused by a medication.
Term
Intertrigo
Definition
Presence of friction, heat, and moisture in areas where two opposing skin surfaces contact each other.
Term
Hirsuitism
Definition
Excessive growth of terminal hair in a male sexual growth pattern.
Term
Alopecia
Definition
What is a condition resulting from effluvium (loss of hair)?
Term
Circatricial Alopecia
Definition
Secondary to damage or destruction of the hair follicle by inflammation, infectious, noninfectious, and/or other pathologic processes.
Term
Noncircatricial Alopecia (nonscarring)
Definition
Which type of alopecia is most common?
Term
Androgenic Alopecia
Definition
Which type of alopecia is considered male/female pattern baldness?
Term
Telogen Effluvium
Definition
Transient increased shedding of normal club hair (telogen) from resting scalp follicles secondary to increased shift of anagen hairs into catagen and telogen.
Term
Telogen Effluvium
Definition
What type of hair loss is usually caused by a traumatic event 6-16 weeks before?
Term
Trichotillomania
Definition
Self induced hair loss usually caused by a habit tic.
Term
Traction Alopecia
Definition
What is localized hair loss secondary to styling?
Term
Anogen Effluvium
Definition
Rapid growth arrest or damage to anagen hairs that skip catagen and telogen and are shed. Secondary to drugs, intoxication, chemotherapy. Pattern follows telogen effluvium. Diffuse and involves the entire scalp. Generally more rapid in onset and more prominent.
Term
Alopecia Areata
Definition
Localized loss of hair in round or oval areas without skin inflammation. Most commonly in the scalp.
Term
Alopecia Totalis
Definition
What type of alopecia has the entire scalp involved?
Term
Alopecia Universalis
Definition
What type of alopecia is seen over the whole body?
Term
Onycholysis
Definition
Separation of the nail from the nail bed.
Term
Beau's Lines
Definition
 Horizontal depression occurring across the nail plate of all the nails.Due to interruption in the growth of the nail occurring during an illness, operation, or even prolonged labor.
Term
Clubbed Nails/fingers
Definition
Loss of the normal angle between the posterior nail fold and the nail plate (Lovibond’s angle).
Term

Koilonychia

 

*spoon nails

Definition
A concavity of the nail plate.
Term
pitting of the nails
Definition
What nail disease is seen in pts with psoriasis or alopecia areata?
Term
Habit tic
Definition
 Repeated scratching of the nail plate or picking at the cuticle damages the nail matrix and the nail grows out in abnormal form.
Term
Leukonychia
Definition
White spots on the nails.
Term
Splinter hemorrhages
Definition

Nail deformity most commonly trauma, but also with

  acute bacterial endocarditis and SLE.

Term
Lamellar Nail Dystrophy
Definition
Splitting of the nail into its component layers.Occurs secondary to repeated wetting and drying out of the nails following frequent immersion in water.
Term

Terry's Nails

 

*Caused by CHF & hypoalbuminemia

Definition
Proximal 2/3 of the nail plate is white and the distal 1/3 demonstrates the normal pink nail bed.
Term

Hutchinson's sign

 

 

Definition
In order to distinguish btwn malignant melanoma of the nail and a hemorrhage you first look for what sign?
Term
Hutchinson's Sign
Definition
Black discoloration of the proximal nail fold at the base of the pigmented streak is an ominous sign for melanoma.
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