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Derm Quiz 2
Derm Quiz 2
65
Other
Graduate
11/23/2009

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Term
: intense, widespread pruritus, intraepidermal burrows with gray or skin-colored ridges that is contracted through skin to skin contact.
Definition
Scabies
Term
:“head lice”, infestation of scalp by head louse
Definition
Pediculosis capitis
Term
:“pubic lice”, infestation of hair-bearing regions, most commonly pubic area, but also hairy parts of chest, axillae, upper eye-lashes, mild to moderate pruritus
Definition
Pediculosis pubis
Term
:STI of the mucocutaneous surfaces of lower genitourinary tract, anorectum, and oropharyx, Clinically in males = purulent urethral discharge, Females = Asx. SX: urethral d/c, dysuria, vaginal d/c, deep pelvic/lumbar pain, copius purulent anal d/c, burning/stinging pain on defecation, tenesmus; blood in/on stool, mild sore throat
Definition
Neisseria Gonorrhea
Term
Describe the findings of primary, secondary and tertiary syphilis.
Definition
Primary - painless chancre.
Secondary - Macules and papules, condylomata lata – soft, flat-topped, moist, red-to-pale papules, nodules, or plaques, generalized eruption on trunk, localized eruption on head, neck, palms, soles.
Tertiary - Gummas
Term
:acute, STI characterized by painful ulcer at site of inoculation, usually on the external genitalia.
Definition
Chancroid
Term
:chronic, progressively destructive bacterial infection of genital region, ulceration and epitheliomatous hyperplasia, button-like papule or subQ nodule that ulcerates w/in a few days, ulcers are beefy-red with sharply defined edges.
Definition
Donovanosis
Term
:STI manifested by infrequent primary genital lesion, secondary lmphadenitis with bubo formation and/or proctitis, and late infrequent sequelae of fibrosis, edema, and fistula
Primary stage - Papule, shallow erosion or ulcer, grouped small erosions or ulcers, nonspecific urethritis, cordlike lymphangitis, bubonulus.
Secondary stage - Inguinal syndrome, Anogenitorectal syndrome, Esthiomene
Definition
Lymphogranuloma venereum
Term
:“genital warts”, soft, skin-colored, fleshy warts occurring on anogenital or oral mucosa of skin, caused by human papillomavirus (HPV), Pinhead papules > cauliflower like masses
Definition
Condylomata acuminate
Term
:STI characterized by primary infection with grouped vesicles at site of inoculation and regional lymphadenopathy & course of recurring outbreaks of vesicles at the same site
Definition
Herpes simplex virus
Term
:small, circumscribed, acquired pigmented macules or papules
Definition
Acquired melanocytic nevocellular nevi
Term
:Macule or only slightly raised > 1.0 cm, Uniform tan, brown, dark brown, Round/oval w/smooth, regular borders; scattered; random, Trunk, upper extremities, face, lower extremities, palmer, or planter. (NEVI)
Definition
Junctional melanocytic Nevi
Term
:Combo of junction and dermal NCN (nevocellular nevi), Usually darkly pigmented, Can be papules or nodules, round/dome-shaped, smooth; often assoc w/bristle-like hairs, Face, scalp, trunk, extremities. (NEVI)
Definition
Compound Melanocytic nevocellular nevi
Term
:papule or nodule; skin-colored/tan/brown often w/telangiectasia, Round/dome-shaped, Face and neck (sometimes on trunk and extremitites). (NEVI)
Definition
Dermal melanocytic nevi
Term
:nevus encircled by a halo of leukoderma or depigmentation, Nevus is centrally located, Oval or irregular; scattered, Trunk
Definition
Halo nevomelanocytic nevus
Term
:Acquired benign, firm, dark-blue to gray-to-black, sharply defined papule or nodule < 10 mm, Localized proliferation of melanin-producing dermal melanocytes, Dorsum of hands/feet
Definition
Blue Nevus
Term
:Small round or oval lesion < 5 mm, Brown or black; occurs anywhere, Can occur as single lesion; in darker ppl – nail bed > linear streaks, or on lip (lower lip esp) = pigmented labial macule, Single or many lesions
Definition
Lentigo simplex
Term
:Lumbosacral area mainly (but also on scalp or anywhere on skin), Congenital gray-blue (usually a single lesion); disappears in early childhood, 99-100% occur in infants of Asiatic and American Indian origin (sometimes in black, rarely in white), No melanomas occur in these lesions
Definition
Mongolian spot
Term
:Asian populations esp (also in East Indians, blacks, rarely whites), Mottled, dusky admixture of blue and brown hyperpigmentation of skin, Esp. on skin and mucosa membranes innervated by 1st & 2nd branch of CNV, Malignant melanoma can occur, but rare
Definition
Nevus of Ota
Term
:Irregularly shaped, red or violaceous, macular, vascular malformation of dermal blood vessels ; present at birth; never disappears spontaneously, 85% unilateral; mostly on face, but can occur anywhere
Definition
Port wine stain
Term
:Dark blue to violaceous, asx, soft papule, Results from dilated venule, Occurs on face, lips, ears in pt > 50, Lesions are few in #, last for years
Definition
Venous Lake
Term
:Formed by cystic enclosure of epithelium w/in dermis, becomes filled with keratin & lipid-rich debris, Rupture common; painful inflammatory mass; young to middle-aged adults; on face, neck, upper trunk, scrotum, Usually solitary, but may be multiple, Contents = cream-colored w/pasty consistency/odor of rancid cheese
Definition
Epidermoid cyst. Synonyms: sebaceous cyst, infundibular cyst, epidermal cyst
Term
:smooth, firm, dome-shaped nodules to tumors (lacks central punctum), 90% occur on scalp, cyst wall thick; contains keratin, very dense, pink, homogenous; often calcified
Definition
Trichilemmal cyst
Term
:Pseudocyst occurring over distal interphalangeal joint and base of nail of finger or toe, Assoc w/ Heberden’s (osteophytic) node, Filled w/clear, gelatinous, viscous fluid, Assoc w/nail plate dystrophy = 1-2 cm groove extending to length of nail, Older pts ~ 60 y/o, Usually solitary cyst, rubbery, translucent
Definition
Digital myxoid cyst
Term
:Most common of benign epithelial tumors, Hereditary, appear around 30 y/o, Rarely pruritic; tender if infected, Starts as macule > “stuck on” appearance (like plaque) > surface appears “warty” w/multiple plugged follicles or “horn cysts”, Brown, gray, black, skin colored; round/oval; scattered; isolated or generalized, On face, trunk, upper extremities
Definition
Seborrheic Keratosis
Term
:Occurs as isolated nodule, usually on face, Presents as dome-shaped nodule w/central keratinous crater, Skin-colored or slightly red, tan/brown; firm; 2.5 cm, Appear on exposed skin; cheeks, nose, ears, hands (dorsa)
Definition
Keratoacanthoma
Term
:Button-like dermal nodule, usually occurs on lower extremities (calves), 3-10 mm; dome shaped; may be dull, shiny, or scaling; top may be crusted or scarred; borders ill-defined, variable in color = skin color, pink, brown, tan, dark brown; darker at center, fading to normal skin color at margin, “Dimple sign”
Definition
Dermatofibroma
Term
:Soft, skin colored, tan, or brown, round or oval, pedunculated papilloma, Usually constricted at base; from 1 -10 mm, Middle aged & elderly, Asx, but may become tender w/trauma, Intertriginous areas (axilla, groin), also on neck, face, eyelids, Larger more numerous over time, esp during pregnancy
Definition
Skin tag
Term
:Single or multiple, benign, subQ tumor composed of fat cells, Soft, rounded, or lobulated, movable , Small > 6 cm, Esp on neck and trunk, also on extremities
Definition
Lipoma
Term
:“white in the mouth”, sharply defined, white, macular or slightly raised area; CANNOT be rubbed off, Premalignant lesion caused by smoking, alcohol, irritation from dentures/jagged tooth
Definition
Oral leukoplakia
Term
:Skin changes resulting from exposure to ionizing radiation, Acute: temporary erythema > blistering/ulceration, Chronic: scars and hypopigmentation, atrophy of epidermis and dermis
Definition
Radiation dermatitis
Term
:Most common type of skin cancer, Limited capacity to metastasize, Papule or nodule, translucent or “pearly” ulcer w/rolled border, Pink or red w/characteristic fine telangiectasia , Depressed center = “umbilicated”, Variants: sclerosing, superficial, and pigmented
Definition
Basal Cell carcinoma
Term
:AKA: Solar keratosis, Precursor to SCC, Due to sun exposed, solar damage
Definition
Actinic keratosis (AK)
Term
:Malignant tumor of epithelial keratinocytes (skin and mucous membrane), Classification: Precancerous intraepithelial lesions, in situ SCC, Bowen’s disease and erythroplasia of queyrat = types of in situ SCC, Slowly enlarging erythematous plaque w/sharp border & little infiltration, Slight scaling, some crusting, When lesion occurs in uncircumcised men (on glans penis, coronal sulcus, inner surface of prepuce), or rarely on vulva = erthroplasia of queyrat
Definition
Squamous Cell carcinoma
Term
:Acquired, circumscribed, pigmented lesions that represent disordered proliferations of variably atypical melanocytes, Asx; appear later in childhood
Definition
Clark melanocytic nevus
Term
:Pigmented lesions of the skin usually present at birth, Very small > very large, benign, Plaque with or w/o coarse terminal hairs; sharply demarcated/regular or irregular borders, Light or dark brown; oval or round
Definition
Congenital nevomelanocytic nevus
Term
:irregular borders, w/”geographic” shape w/inlets & peninsulas. Sharply defined, 3-20 cm or larger; uniformly flat, macule, o Older persons; sun exposed areas, Focal popular and nodular areas
Definition
Lentigo maligna/lentigo maligna melanoma
Term
:Most frequently on upper back, Flattened papule > plaque > 1/more nodules, Dark brown, black, with admixture of pink, gray, and blue-gray hues; 8-12 mm (average); asymmetrical, oval w/irregular borders w/one or more indentations; sharply defined
Definition
Superficial spreading melanoma
Term
:Occurs largely in middle life in persons w/white skin on less commonly exposed areas, Presents as thick plaque or nodule, “Blueberry-like” nodule or ulcerated or “thick”, dark blue, black, or “thundercloud” gray; 1-3 cm; oval or round; smooth, not irregular borders
Definition
Nodular melanoma
Term
:Hairlike filiform papillae become increased in length/thickness, Usually pigmented “black” related to overgrowth of pigment-forming bacteria
Definition
Hairy Tongue
Term
:Common, benign, asx disorder; changes in dorsum of tongue, Numerous linear “valleys”, Synonym: “scrotal” tongue
Definition
Fissured tongue
Term
:Present as reddish-white areas of tongue (most pts have fissured tongue), Sharply demarcated areas with white rim and depapillation of tongue surface, Irregular, “geographic,” map-like
Definition
Migratory glossitis
Term
:Painful mucosal ulcerations, Characterized by pain & sharply marginated gray-based red-rimmed ulcers
Definition
Aphthous ulcer
Term
:Painless, translucent, blister-like swelling of the mucous membrane; easily ruptured, drains a clear fluid and then refills, found in areas of the mouth where salivary glands are exposed to trauma
Definition
Mucocele
Term
:Circumscribed mass of dense submucosal connective tissue, sessile or pedunculated; pink to pink-red; firm to hard submucosal nodule
Definition
Oral fibroma
Term
:Loss of hair in round or oval areas w/o any visible inflammation of the skin in hair-bearing areas; most common presenting site = scalp
Definition
Alopecia areata
Term
:loss of all scalp hair and eyebrows
Definition
Alopecia totalis
Term
:end stage of alopecia areata; complete loss of body hair
Definition
Alopecia universalis
Term
:Common progressive balding, occurs through combined effect of genetic predisposition & action of androgen on hair follicles of scalp, Bitemporal recession > frontal and/or vertex thinning > loss of all hair, Gradually thinning hair or baldness
Definition
Androgenetic alopecia
Term
:Thinning of hair, May also affect nails > Beau’s lines = transverse lines or grooves on fingernail and toenail plate
Definition
Telogen Effluvium
Term
:Damage or destruction of hair follicles by inflammatory or other pathologic processes, and healing occurs with scarring, Scarring, atrophy, complete loss of hair follicles
Definition
Scarring alopecia
Term
:o Infection of upper portion of hair follicle
:follicular papule, pustule, erosion, crust at follicular infundibulum, May cause sycosis = papulopustular inflammation of hair follicles, esp beard, Papule or pustule surrounded by erythematous halo
Definition
Infectious folliculitis
Term
:Excessive hair growth in androgen dependent hair patterns (face, chest, areolae, linea alba, lower back, buttocks, inner thighs, external genitalia) 2nd to increased androgenic activity
Definition
Hirsituism
Term
:Excessive hair growth in areas that are not androgen sensitive, Hair may be > 10 cm in nonscalp areas; involve entire body except palms/soles, Fine, downy hair covers large areas of the body
Definition
Hypertrichosis
Term
Most common tumor affecting the nails?
Definition
Squamous cell carcinoma
Term
:Acute, delayed, transient inflammatory response of skin following exposure to ultraviolet radiation, Erythema, may present w/vesicles and bullae, edema, tenderness, pain, Sx: Asx > pruritis > pain > tenderness
Definition
Acute sun damage (sunburn)
Term
:Repeated solar injuries over many years, Wrinkled, leathery, “prematurely aged”, “looks old but is young.” Telangiectasia, purpura, and easy bruising.
Definition
Dermatoheliosis
Term
:1-3 cm brown macule resulting from proliferation of melanocytes due to chronic exposure to sunlight, Light yellow, light brown, or dark brown (not uniform color), Round, oval, slightly irregular borders
Definition
Solar lentigo
Term
:single/multiple, discrete, dry, rough, adherent scaly lesions occurring in sun-exposed skin
Definition
Solar keratosis AKA Actinic keratosis
Term
:Inflammation of skin caused by contact w/certain plants during, and subsequent to, exposure to sunlight, Marked pruritis, Erythema, vesicles, bullae, Dark hyperpigmentation in bizarre streaks
Definition
Phytophotodermatitis
Term
What are the 3 patterns of Phototoxic drug-induced photosensitivity?
Definition
3 patterns:
Immediate erythema and urticaria.
Delayed sunburn-type pattern.
Delayed melanin hyperpigmentation.
Term
:Most common of photodermatoses, Describes a group of photodermatoses characterized by delayed abnormal reactions to UV radiation, manifested by varied lesions, Average age = 23; females, Pruritus & paresthesia, Papules & papulovesicules = most common lesions (plaques or urticarial plaques = less common), Lesions are pink to red
Definition
Polymorphous light eruption
Term
:Complaints of “fragile skin”, vesicles, bullae, esp on dorsa of hands following minor trauma
Definition
Porphyria cutanea tarda
Term
:Bullous autoimmune dz of skin and mucous membranes; often fatal unless treated w/immunosuppressive drugs, 40-60 y/o, starts in oral mucosa > acute eruption of bullae; painful tender mout lesions prevent adequate food intake, other sx: epistaxis, hoarseness, dysphagia, Nikolsky’s sign: pressure on bulla leads to lateral extension of blister
Definition
Pemphigus vulgaris
Term
:Autoimmune disorder presenting as chronic bullous eruption mostly in pts > 60 y/o, Prodromal eruption (urticaria) > bullae, Erosions, erythematous, urticarial-type lesions; bullae, large, tense, firm-topped
Definition
Bullous Pemphigoid
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