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Derm/EENT Module 13
Derm/EENT Module 13
32
Pharmacology
Graduate
04/15/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Ointment
Definition
Oily with little water
Best used to lubricate
Term
Creams
Definition
Emulsions of oil in water
Easy to apply then vanish
Term
Lotions
Definition
Water, alcohol or oily
Convenient to apply, drying
Term
Solutions
Definition
Drying
Vehicles are alcohol, propylene glycol, water
Term
Emollient (Eucerin)
Definition
"Anti-itch" - pruritus
MOA: soothes skin
KIN: applied after bath, apply thin layer to dry skin
Term
Hydroxyzine (Vistaril)
Definition
Pruritus
Vistaril in adults; Benadryl in kids
MOA: discourage the effort to scratch
KIN: PO TID
SE: sedation
generally given for older people
Term
Prednisone
Methylprednisolone
Dexamethasone
Definition
Corticosteroids
Acute tx of transient illness; Manage life-threatening dermatoses
KIN: given as tapered dose
Term
Diphenhydramine (Benadryl)
Doxepin (Sinequan)
Definition
Benadryl - elixir hs for kids
Sinequan - for adults
Term
Pimecrolimus 1% cream (Elidel)
Definition
MILD TO MODERATE atopic dermatitis
use when others have failed
SE: pruritis, burning sensation
BB: rare cases of cancer (skin, lymphoma)
Avoid long term use and sunlight
Term
Tacrolimus ointment (Prograf)
Definition
MODERATE TO SEVERE atopic dermatitis
use when others have failed
SE: pruritis, burning sensation
BB: rare cases of cancer (skin, lymphoma)
Avoid long term use and sunlight
Term
Nystatin (Mycostatin)
Definition
Skin, vaginal infection; oral candidiasis
PO & topical
Term
Fluconazole (Diflucan)
Definition
DOC
Oral esophageal candidiasis in AIDS pts
Prophylaxis of vaginal candidiasis
PO
Term
Tretinoin (Retin-A)
Definition
DOC for mild to moderate comedonal & inflammatory acne
MOA: modulate epithelial keratinization & inflam, dec formation of cmedones
KIN: cream & gel, apply nightly, takes 6-12 weeks for full effect
SE: photosensitivity, erythema, dryness
Avoid excessive use and contact with mucous membranes
Term
Benzoyl Peroxide 5 or 10%
Definition
1st line tx for mild to moderate noninflammatory acne
MOA: penetrates striatum, contact sensitizer, bleaching agent
KIN: applied QD, start c low concentration to decrease irritation
Term
Isotretinoin (Accutane)
Definition
*Use if all other tx's fail*
Severe recalcitrant nodular acne
KIN: lesions get worse before it gets better
SE: dryness of conjunctiva & lips, photosensitivity
C/I: PG cat X
2 pages of BB warnings
All pts, HCP, & pharmacist must register c SMART system
Term
1st line therapy: Impetigo
Definition
topical Mupirocin ointment TID for 7-10 days
Term
1st line therapy: Mild Cellulites
Definition
broad-spectrum penicillin (amox/clav or dicloxacillin)
Term
1st line therapy: Pustular Infections
Definition
warm compresses, topical tx with Mupirocin, gentamicin, bacitracin (systemic therapy may not be needed)
Term
1st line therapy: Paronychia
Definition
systemic antibiotics (amox/clav, Cephalexin, dicloxacillin, erythromycin)
Term
Mupirocin (Bactroban ointment)
Definition
Rx only
DOC for minor impetigo
Tx skin infections 2' staph & various strep; gram + bacteria
Term
Gentamicin (Garamycin cream or ointment)
Definition
more effective against staph & beta-hemolytic strep than neomycin
Term
Acyclovir
Definition
topical - 1st line for HSV-1
oral - 1st line for VZV
Term
Valcyclovir
Definition
oral - 1st line for herpes zoster
Term
Psoriasis agents
Definition
1st line: moisturizers (emoillients - Eucerin, Lubriderm) & topical steroids
2nd line: reapplication of steroid after a weeks rest, possible add a vit D analog
3rd line: referral to dermaologist
Term
Procaine (Novocain)
Definition
Local anesthetic - esters
Temporary relief of pain and itching - usually on mucus membranes; anal/vulvae pruritus, hemorrhoids
MOA: prevent/suppress pain sensation by acting on peripheral sensory nerves
KIN: topical or injection
SE: sensitization
C/I: app to throat may suppress swallowing, cough, gag reflex
Term
Prednisolone (PredForte)
Definition
Corticosteroid
Tx: responsive inflammatory conditions - allergic conjunctivitis, keratitis
MOA: exert an anti-inflammatory action
KIN: relieves itching, redness
Term
Cromolyn (Cromolom)
Definition
Mast cell stabilizer
Tx: various inflammatory d/o - conjunctivitis, keratitis
MOA: mast cell stabilizers that inhibit hypersensitivity reactions
Term
Timolol (Timoptic)
Definition
Beta-Blocker
1st line agent for primary open-angle glaucoma
MOA: ophthalmic drops reduce IOP by decreasing production of aqueous humor
SE: may cause systemic effects
Term
Latanoprost (Xalatan)
Definition
Prostaglandin analog
Tx: glaucoma
MOA: lower IOP by facilitating aqueous humor outflow by relaxing ciliary muscle
SE: pigmentation of eyelid, blurred vision, local burning/stinging
Term
Tetrahydrozoline (Visine)
Definition
OTC antihistamine for relief of itching and redness - minor eye irritation
Term
Otitis Media
Definition
DOC - amoxicillin
resolves spontaneously in 80% of children
Term
Otitis Externa "swimmer's ear"
Definition
1st line drug: fluoroquinolone (Cipro)
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