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DentSci Final
Science
65
Science
Advanced
06/06/2019

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Term
Acute Pain
Definition
Peripheral, protective and localized, pain is a symptom, appropriately relieved. Anxiety usually dissipates.
Term
Chronic Pain
Definition
Peripheral + Central Sensitization. No useful benefit, CNS-Oriented Changes, its own disease. (NT Changes, changes in size of receptor field in sensory cortex), neuroplasticity changes, assoc with psychological problems.
Term
Stages of Swallowing
Definition
1) Preparatory
2) Oral
3) Pharyngeal
4) Esophageal Transport
Term
Tension produced by a group of muscle fibers depends on
Definition
1) Cross sectional area
2) Amount of EMG recruitment
Term
Signs and symptoms of Bruxism
Definition
Sensitive painful teeth
Occlusion related periodontal pain
Worn/Cracked/Fractured teeth and restos
Abnormal tooth mobility
WIDENED PDL
Fremitus
Muscles are resistant to fatigue and pain goes away quickly
Term
Asymptomatic DD w/ R
Definition
Condyle re-establishes a normal anatomic relationship with disc during condylar translation. Common in asx volunteers (TMJ clicking, normal ROM, no pain). Normal biological variation unless outside RFs are present.
Term
Symptomatic DD w/ R
Definition
More problematic clicking: condyle catches, cant get past disc, impeded for seconds/minutes, muscles relax, then click -> rest of ROM is comfortable.

Episodic difficulty/pain with possible disc, synovium or capsule impingement. Pain at time condyle re-establishes normal anatomical relationship with disc.
Term
Acute Disc Displacement w/o R
Definition
Condyle fails to re-establish a normal anatomical relationship with disc during condylar translation/rotation, occurs within the last 3 months going from clicking -> abrupt loss of clicking and movement.

Joint pain is provoked by function, limited ROM because condyle can't get past disc.

MARKED LIMITED LATEROTRUSION to the contralateral side. Chronic is more than 3 months.
Term
Synovitis
Definition
Localized joint pain provoked by palpation, loading or function. Fluctuating swelling w/ separation of posterior occlusion. Probable marked decrease in mobility. Possible radiographic increase in superior joint space.

Secondary to infection, trauma, or cartilage degradation.
Term
Capsulitis
Definition
Localized joint pain provoked by joint distraction or exterior/extended function. Fluctuating swelling with separation of posterior occlusion. Probable marked decrease in mobility, possible radiographic increase in joint space.

Secondary to infection, trauma or cartilage degradation.
Term
Polyarthritides
Definition
Localized joint pain provoked by palpation, loading or function. Bilateral joint inflammation and structural changes secondary to a general systemic polyarthritic condition. Probable marked decrease in mobility, possible decreased joint space and crepitus.

Pt needs blood panel and serology tests to look for markers of RA/Lupus. Joint is cupped out , top 2/3rd of condyle is missing, round part of articular eminence is gone, joint becomes shorter by 6-7mm -> anterior open bite.
Term
Osteoarthritis
Definition
Painful inflammatory degenerative condition characterized by progressive deterioration and abrasion of the articular surfaces. Usually self-limiting.

Jt pain at rest and function, crepitus, limited ROM with deflection secondary to pain. possible changes in posterior occlusion. Radio: Loss of cortical integrity, possible bone spurs, subchondral bone cysts, narrowed superior jt space.
Term
Osteoarthrosis
Definition
Nonpainful, non-inflammatory degenerative condition characterized by degeneration of articular tissues due to the overload of the remodeling system. Condyle is melting down and we can't figure out why the jaw keeps falling back down despite elastics.
Term
Juvenile Idiopathic Arthritis
Definition
Spontaneous lytic event -> condyle becoming rapidly and progressively smaller and in some cases disappears. Pt becomes severely retrognathic due to rapid resorption of bone in 2-3mos. Typically painful but not always.

66% malocclusion
30% micrognathia

No association between radiographic findings and symptom severity. Condylar resorption. If left condyle is abnormal, then the mandible will shift to the left.
Term
Dislocation
Definition
Open lock secondary to hypermobility, condyle remains positioned anterior to the articular eminence, usually influenced by increased muscle activity and ligamentous laxity.

CP: Inability to close, jt pain at time of [term], usually with a history of doing so.
Term
Ankylosis
Definition
Nonpainful restricted ROM with deflection to affected side, resulting from adhesions/bony proliferations, usually secondary to trauma, polyarthritides or surgery. Marked limited lateral movement to contralateral side + absences of condylar translation.
Term
Etiology of Peripheral Sensitization
Definition
1) Ischemia with prolonged muscle contraction <-- Metabolites: Lactic Acid, ATP, ADP, pH changes.
2) Tissue injury --> Inflammation --> Nociceptor excitation.
3) Spontaneous activation of deep nociceptors -> increase in NGF, glutamate, SP, Histamine
Term
Etiology of Central Sensitization
Definition
1) Sympathetic hemodynamic change (stress)
2) Increase in nociceptive afferent barrages -> increase in SNC. Increase in excitatory AAs and neuropeptides.
3) Decrease in descending anti-nociceptive modulation: serotonin, NA, endogenous opioids.
Term
Myalgia
Definition
Muscle tenderness in palpation.
Term
Myofascial Pain
Definition
Provoke referred pain to other structures via palpation
Term
Myospasm
Definition
aka Trismus. Acute, sudden, involuntary tonic contraction of muscle (usually medial pterygoid). Acute onset of pain, pain at rest w/ function, increased EMG activity at rest.

May be associated with myositis or local infections.

E: Multiple injections, prolonged stretch/overuse of unconditioned muscles, abrupt/unusual movements.
Term
Tendonitis
Definition
Tendinous infection secondary to direct trauma, repetitive strain, or injury. Acute pain, extreme tenderness with palpation, limited ROM.

Prolonged recovery, slow responders.
Term
Myositis
Definition
Muscular tissue inflammation usually secondary to direct trauma or spreading infection. Constant, acutely painful muscle with diffuse tenderness, edema, erythema and increased temperature + limited ROM.
Term
Contracture
Definition
Painless shortening of the muscle, and chronic resistance to passive stretch as a result of FIBROSIS of supporting tendons, ligaments or the myofibers themselves.

Limited ROM, hard-end feel, little to no pain unless forcefully lengthened.

E: Long periods of limited ROM, muscle infection, direct trauma, scarring, surgery or radiation therapy.
Term
Polyarthritic (of JIA)
Definition
Affects more than 5 joints in 1st 6 months. 75% of patients have radiographic TMJ damage.
Term
Oligoarthritic (of JIA)
Definition
Affects 4 or less joints in 1st 6 months. 20% of patients have radiographic TMJ damage.
Term
Histology of JIA
Definition
Inflammatory cells invade the TMJ + Hyperplasia of synovial tissues, shows classic features of RA.

Increase in estrogen and relaxin leads to increase cartilage degradation via MMPs.

Decrease in estrogen leads to increase in bone lysis due to increase in osteoclast activity, number and size. Increase in remodeling rate, increase in trabecular spaces and decrease in trabecular connectivity.
Term
Hyperalgesia
Definition
Lowered pain threshold
Term
Allodynia
Definition
Pain to non-painful stimuli
Term
Hypoalgesia
Definition
Increased pain threshold
Term
Somatization
Definition
increased awareness of physical symptoms.
Term
Primary afferent fibers
Definition
A-Delta and C fibers (plus A-Beta when it gets confused with the trigeminal) via the lateral and medial spinothalamic tract.
Term
Ascending
Definition
1) Central sensitization: Release of excitatory NTs (Substance P, Glutamate, CGRP) sensitizing secondary WDR neurons. in CNS
2) Peripheral: Releasing excitatory AAs (Substance P, NMDA, ATP) occurs at the Trigeminal Ganglion, increasing activity and pain.
Term
Descending
Definition
Midbrain: Periaqueductal Grey
Pons: Locus Coerulus
Medulla: Nucleus Raphe Magnus

Release inhibitory NTs: Endogenous opiates, NA, Serotonin, GABA, NMDA, Substance P Antagonists.
Term
TAC Headaches
Definition
Unilateral conjunctivitis, lacrimation, rhinorrhea, miosis, ptosis, eyelid edema
Term
Giant Cell arteritis
Definition
Temporal artery becomes dilated -> pain upon palpation + jaw pain secondary to claudication. Ischemic optic nerve -> blindness in 1/3rd of patients.
Term
Intercranial headaches warning signs and symptoms
Definition
Constant/dramatically worsening pain
Sensory/motor neurological deficits
Pain unrelated to physical findings, provocation or function.
Decrease in general health, complaints or multiple failures.
Severe pain with sudden onset
Term
Headache attributed to cervical region
Definition
Cervical facets, C1,2,3 peripheral nerves, cervical muscles. Common.
Term
Extracranial Disease
Definition
Attributed to TMD: Myalgia, myofascial pain, arthralgia with secondary myalgia.
Term
Episodic Neuralgias
Definition
1) Trigeminal
2) Glossopharyngeal (Rare)
3) Occipital
4) Nevus Intermedius, Superior Laryngeal (rare)
Term
Trigeminal Episodic Neuralgia
Definition
Unilateral icepick pain, sudden, sharp with severe intensity, seconds to 2 minutes, >50yo, F>M, no neurological deficits, no pain in between episodes, treat with:

Membrane stabilizers
Baclofen
Klonopin, Surgery
Term
Persistent Neuralgias
Definition
1) Neuroma
2) Persistent Idiopathic facial pain
Term
Neuroma
Definition
Persistent pain from compression/irritation. Occurs at the end of injured nerve fibers as a form of ineffective/unregulated nerve regeneration.

Tx: LAs and corticosteriods, surgical ablation.
Term
Persistent Idiopathic Facial Pain
Definition
Nervous system injury/dysfunction, occurs in absence of tissue damage -> chronic pain. Associated with PN/CN sensitization.

EG Burning mouth syndrome w/ taste dysfunction. 30-40 yos, mod to severe constant pain for months-years, repeated dental failures
Term
Neuropathic pain risk factors for Post-Traumatic Trigeminal Neuralgias
Definition
History of chronic pain disease
Pre-Treatment pain
Fear of Pain
Incomplete Anesthesia
Constant persistent pain related to dental treatment (2-5% of endo pts)
Term
Masseter (middle)
Definition
Lower and upper molar teeth, gingivae, and maxilla. Assoc with sinus headache?
Term
Dermatome Pain
Definition
Noxious stimuli -> Subnucleus caudalis -> Thalamus -> Sensory cortex.

Temporalis and tooth-associated pain -> Lamina 3 in subnucleus caudalis.
Term
Temporalis (anterior)
Definition
Forward along supraorbital ridge and maxillary incisors
Term
Temporalis (posterior)
Definition
Temple and maxillary molars
Term
Temporalis (intermediate)
Definition
Up to mid-temple area and down to maxillary bicuspids.
Term
Medial Pterygoid
Definition
Diffusely to mouth, below and behind TMJ and ear, NOT TO TEETH. Jaw and Face.
Term
Lateral Pterygoid
Definition
Deeply to TMJ and maxillary sinus. NOT TO TEETH. Jaw, sinus, paranasal regions
Term
Digastric
Definition
4 mandibular incisors and alveolar ridges.
Term
Splenius Capitus
Definition
Vertex on same side (Top of head)
Term
Semispinalis Capitus
Definition
Forward to temple and forehead over eye, temporal region
Term
Trapezius (upper)
Definition
Up along posterolateral neck to mastoid process, temple, back of orbit, angle of jaw.
Term
Trapezius (lateral)
Definition
Up more posteriorly than posterolateral neck to mastoid process, temple, back of orbit, angle of jaw.
Term
Trapezius (lower)
Definition
Superior cervical region, adjacent to mastoid area and acromion.
Term
Occipital
Definition
Laterally and diffusely over the back of head and through cranium causing intense pain deep into orbit
Term
SCM (Sternal)
Definition
Cheek, maxilla, over supraorbital ridge, deep within orbit, face
Term
SCM (Upper Clavicular)
Definition
Top of head and posterior auricular regions
Term
Types of neuogenic (primary) headaches
Definition
1) Migraine HA
2) Migraine variant HA
3) Tension-Type HA (with and without pericranial muscle tenderness)
4) Cluster HA and other autonomic cephalgias
Term
Paroxysmal Hemicrania
Definition
Primarily adult females around 30yo, at least 20 shorter acting attacks with more than 5/day. Severe unilateral, orbital, supraorbital and/or temporal pain for 2-30 mins. Assoc w/ at least 1 of Horner's Signs.

Female version of cluster headaches.

Med: Indomethacin.
Term
Post-Traumatic HAs
Definition
Truama, no association between severity of injury and severity of HA, associated with faintness, poor concentration/memory, anxiety, insomnia.

Interruption of EEG signals -> lowered reaction times.
Term
Meds for sleep bruxism
Definition
Benzodiazepines (Clonazepam)
Muscle Relaxants (Flexeril)
Tricyclics (Pamelar, Doxepin)
Anticonvulsants (Gabapentin)
Botox
Occlusal splints/nightguards.
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