-Fast onset (20-40 mins)

-Doses range 2-10 mg

-long elimination 1/2 life (20-80 hours)

-Intermediate-acting BDZ (elim. 1/2 life 10-20 hours)

-generally longer sedative effect because it has lower lipid solubility which slows its redistrubition from the brain

-less affected by variables such as advanced age, hepatic dysfunction, or drug-drug interations 

-used for tx of insomnia

-rapid onest, short DOA, lack of active metabolites = NEAR IDEAL ANTIANXIETY MED FOR DENTAL PTS

-onset witin 30 mins

-peak occuring 75 mins 

-Dose : .125-.5

-can be influenced by aging, hepatic dysfunction, drug-drug interactions becaues it is metbolized via cytochrom p450 system in the liver