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Study of Prenatal Development |
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First week (day 1-7), begins with fertilization, zygote undergoes mitosis |
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Hollow ball with 2 layers
Trophoblast = outside, embryoblast = inside
implants in the uterine wall
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cells digest the uterine wall and insert its own into the wall; it gives rise to support tissues |
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2nd to 8th week (day 7-56)
period of rapid growth and differentiation
when differentiation and morphogenesis takes place, the embryo is most susceptible to disturbances at this time |
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When cells move and develop into something (bones, cells, skin muscle celss etc)
action group of one group of cells on another that leads to the establishment of the developmental pathway in the responding tissue |
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controlled cellular growth and accumulation of byproducts |
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layered growth of a firm or hard tissue such as cartilage, bone, enamel, dentin, cementum |
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Change in embryonic cells to become quite distinct structurally and functionally |
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development of specific tissues and systems
development of specific tissue structure or differing form due to embryonic cell migration |
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Attainment of adult function and size due to proliferation, differentiation and morphogenesis |
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Epiblast and hypoblast layers
suspended between two fluid filled cavities (amniotic cavity)
circular plate of bilayered cell developed from blastocyst |
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Superior layer in bilaminar disc
composed of high columnar cells |
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Inferior layer in bilaminar disc
composed of small cuboidal cells |
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Migratory cells that locate in the middle between the epiblast and hypoblast layers
Embryonic connective tissue
develop in the midline of the floor of the pharynx |
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Layer in trilaminar embryonic disc derived from EPIBLAST
Top layer |
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embryonic layer between ectoderm and endoderm
middle layer |
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layer in trilaminar embryonic disc derived from HYPOBLAST layer
botom layer |
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membrane at cephalic end
mouth |
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Membrane at caudal end
anus |
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a band of cells that extend from the cepahlic to the caudal end grows and thickens |
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specialized group of cells that differentiates from ectoderm |
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formed when neural plate undergoes groth and thickening, causing it to invaginate |
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developed from neuroectoderm that migrate from the crests of the neural folds and disperse to the specific sites within the mesenchyme |
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38 paired cuboidal aggregates that develop along the midline of the neural tube |
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Development of the Face and the Neck |
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*4th week brain and heart growing rapidly
*Oropharyngeal (Buccopharyngeal) membrane sandwich inbetween
*Oropharyngeal membrane lines the stomodeum (primitive mouth) and separates the future oral cavity from the future pharynx |
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Primitive mouth
little invagination |
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Growth is initially more rapid than the lower face
it develops by fusion of tissue |
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Bulge of tissue in the most cephalic end of embryo
gives rise to the upper face, nose, primary palate, eyes and internal ear |
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develops from the primitive pharynx and the branchial apparatus |
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includes branchial arches, branchial grooves and membranes and pharyngeal pouches |
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specialized thickened ectoderm taht develop into sense organs |
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form pits that become the inner ear |
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form pits and form the nasal cavity |
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are formed when the center of the nasal placodes submerge
they deepen toward the brain
separated from the stomodeum by the oronasal membrane |
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membrane taht disintegrates leaving nasal and oral cavities in communication |
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develop from crescent shaped swellings |
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2 swellings between the nasal pit
grow and fuse to form the middle portion of the nose from the root to philtrum |
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2 swellings on the outer portion of the nasal pits
grow and fuse to form the alae of the nose |
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growth from paired medial nasal processes on inside of stomodeum
involved with forming the nasal septum, anterior portion of the palate and maxillary incisors aka globular processes)
forms from the fusion of the 2 medial nasal processes |
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Branchial arches (pharyngeal arches) |
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6 pairs of U-shaped bars of tissue inferior to the stomodeum
formed by crest cells
covered with ectoderm, lined with endoderm with a core of mesenchyme
bilateral, oriented anterior-posterior they bend to surround and supprt the pharynx |
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develop greatest and are involved in formation of the face |
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involved in the formation of the neck |
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rudimentary, absent or included with the 4th |
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processes of the first branchial arch that fuse at midline to form mandibular arch |
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First Branchial arch (mandibular) |
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formed by the fusion of the 2 mandibular processes in the 4th week
located below the stomodeum
muscles of mastication, suprahyoid muscles, the tongue, and some palatal muscles, trigeminal nerve |
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template for formation of mandible and contributes to formation of middle ear |
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swelling that develop from the mandibular arch also during the 4th week
bilateral to the stomodeum, swellings grow superior and anterior
fuse with globular processes of the frontonasal process to form the upper lip and is completed during the 6th week
also forms cheeks along wit the zygomatic bones, secondary palate and posterior portion of the maxilla along with the associated teeth and tissues |
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failure of fusion of the maxillary processes with the globular process of the medial nasal process
failure to fuse can be unilateral or bilateral, incomplete or complete, more common in boys |
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responsible for some bones of the middle ear, part of the temporal bone, and part of hyoid bone |
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2nd Branchial arch (Hyoid arch) |
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arch - muscles of facial expression, suprahyoid muscle, tongue, facial nerve (VII) |
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between branchial arches
the first one remains becoming the tympanic membrane, others obliterate as the hyoid arch grows inferiorly - results in a smooth neck |
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forms between 1st and 2nd arches
becomes auditory nerve |
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3rd & 4th pharyngeal pouch |
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form the thymus and the parathyroid glands |
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remnants of tissue
a disturbance seen when grooves don't become obliterated |
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formed from the foregut
lined with endoderm
joins stomodeum and the esophagus
outgrowth forms: larynx, trachea, thyroid gland and ends in the superior portion of the lungs |
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anterior part of future digestive tract or primitive pharynx that forms oropharynx |
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