Term
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Definition
progressive loss of brain function characterized by memory loss, confusion, and dementia |
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Term
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Definition
progressive weakness and wasting of muscles caused be destruction of motor neurons |
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Term
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Definition
autosomal dominant genetic disorder resulting in progressive dementia and involuntary, spasmodic movements of limb and facial muscles |
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Term
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Definition
demyelination of neurons in the CNS resulting in progressive weakness, visual disturbances, mood alterations, and cognitive deficits |
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Term
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Definition
progressive loss of dopamine in the CNS, causing tremor, muscle rigidity, and abnormal movement and posture |
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Term
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Definition
parkinson's med Levadopa takes _____ to see maximum effects |
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Term
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Definition
antiparkinsons drugs have ______ effects |
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Term
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Definition
most serious side effect of antiparkinsons meds |
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Term
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Definition
involuntary, forcible, rapid, jerky, movements that may be subtle or become confluent, markedly altering normal patterns of movement |
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Term
carbidopa-levodopa (Sinemet) |
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Definition
drug that prevents the metabolism of levodopa, - enhances dopamine action |
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Term
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Definition
chemical precursor to dopamine |
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Term
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Definition
levadopa dose can be reduced by _____ if given with carbidopa |
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Term
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Definition
levadopa can't be used in pts w/ _____ or using __ |
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Term
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Definition
foods high in ____ reduce the efforts of levodopa |
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Term
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Definition
____ is a normal s/e of dopaminergic meds |
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Term
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Definition
anticholinergics used to treat parkinsons in elderly beause less s/e |
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Term
Benadryl - benztrophine(Cogentin) |
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Definition
2 drugs used to control extrapyramidal disorders |
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Term
amantadine digoxin Haldol phenothiazines |
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Definition
4 drugs that antiparkinson's cholinergic blockers interact with |
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Term
acetylcholinesterase inhibitors |
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Definition
alzheimers disease is treated with ______ |
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Term
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Definition
preferred drug for mild to moderate dementia |
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Term
nausea diarrhea muscle cramps weight loss |
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Definition
donepezil (Aricept) may cause ___ (4) |
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Term
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Definition
new drug for alzheimers that prevents damage to brain neurons associated with excess glutamate release |
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Term
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Definition
alzheimers drug that causes hepatotoxicity |
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Term
aricept exelon cognex reminyl |
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Definition
four alzheimers drugs used to increase acetylcholine in CNS by inhibiting breakdown of neuronal pathways and slowing destruction |
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Term
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Definition
a combination of ____ and ___ shows best results for alzheimers in that it slows the symptoms |
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Term
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Definition
alzheimers drugs focus on improving _____ |
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Term
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Definition
drug given 3-4 times per day on an empty stomach |
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Term
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Definition
w/in ___ of d/c anticholinesterase all benefits are lost |
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Term
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Definition
herbal supplement used for improving memory |
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Term
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Definition
drug type used to decrease the overall relapse rate of MS |
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Term
interferon beta la(avonex, rebif) |
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Definition
example of immunosupressant drug used for MS |
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Term
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Definition
______ should be used cautiously in suicidal tendancies, depression, bone marrow depression, seizure and thyroid disorders, liver problems |
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Term
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Definition
_____ can cause alopecia which is ussually temporary |
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Term
modafinin(Provigil) amantadine (symmetrel) |
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Definition
2 drugs used to treat fatigue, memory loss, and progressive weakness of MS |
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Term
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Definition
drug used to treat insomnia, anxiety, and sensitivity to pain of MS |
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Term
Methylprednisolone (Solumedrol) |
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Definition
drug used to treat the acute inflammation of the CNS system with MS |
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Term
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Definition
rapidly repeating muscle spasms |
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Term
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Definition
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Term
upper motor neuron activity |
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Definition
many muscle relaxants treat muscle spasms by inhibiting _________ causing sedation or altering simple reflexes |
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Term
baclofen(Lioresal) diazepam(Valium) |
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Definition
two drugs that relax muscles by acting on the CNS system to interfere with the release of Ca ions |
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Term
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Definition
muscle relaxant that acts directly on the muscles, not the CNS |
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Term
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Definition
neuromuscular blocking agents block the effect of ________ at the receptor |
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Term
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Definition
neuromuscular blocking agents bind to ______ receptors located on the surface of skeletal muscle |
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Term
nicotinic blocking agents |
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Definition
another name for neuromuscular blockers |
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Term
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Definition
neuromuscular blocking agents are anticholinergic or cholinergic |
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Term
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Definition
neuromuscular blockers prevent _____ muscle contraction |
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Term
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Definition
neuromuscular blockers that competes with acetylcholine for the receptor - muscle remains relaxed |
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Term
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Definition
neuromuscular blockers that bind to the acetylcholine receptor - muscle is continuously depolarized |
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