Term
antimetabolites
What are the three? |
|
Definition
Sulfanamides
Trimethoprim
Isoniazid |
|
|
Term
antimetabolite
Sulfanamides
Function? |
|
Definition
| stop DNA syn via folic acid |
|
|
Term
antimetabolites
Trimethoprim
Function? |
|
Definition
| inhibits dihydrofolate reductase |
|
|
Term
Antimetabolites
Isoniazid
Function? |
|
Definition
stops M. tuberculosis via mycolic acid
(inhibits InhA an elongation enzyme) |
|
|
Term
Bactrim
What is it and what is it good for?
|
|
Definition
A combo of trimethoprim and sulfa
good for uti |
|
|
Term
What are some sulfas good for and why?
ie. Bactrim |
|
Definition
UTI
that is where they are concentrated |
|
|
Term
Inhibitors of wall synthesis
limited spectrum
what are they? |
|
Definition
penicillin G
Penicillin V |
|
|
Term
Inhibitors of wall synthesis
broad spectrum
what are they? |
|
Definition
|
|
Term
Inhibitors of wall synthesis
extended spectrum
what are they? |
|
Definition
Tricarcillin
Piperacillin |
|
|
Term
Inhibitors of wall synthesis
penicillinase resistant
what are they? |
|
Definition
|
|
Term
Inhibitors of wall synthesis
limited spectrum
what do they kill? |
|
Definition
|
|
Term
Inhibitors of wall synthesis
broad spectrum
what do they kill? |
|
Definition
| most G+ and G- enteric bacilli |
|
|
Term
Inhibitors of wall synthesis
extended spectrum
what do they kill? |
|
Definition
will kill most G- bacilli less effective against G+
effective against pseudomonas |
|
|
Term
Inhibitors of Cell Wall
What penicillins are resistant to penicillinase? |
|
Definition
Methicillin
Oxacillin
called antistaphy antiboitics |
|
|
Term
Inhibitors of cell wall
Name a 1st generation Cephalosporin |
|
Definition
|
|
Term
Inhibitors of cell wall
Name a 2nd generation Cephalosporin |
|
Definition
|
|
Term
Inhibitors of cell wall
Name a 3rd generation Cephalosporin |
|
Definition
|
|
Term
| what does ceftriaxone and cerftazdimen kill? |
|
Definition
most G-
with
ceftriaxone against Pseudomonas
cerftazdime in CNS |
|
|
Term
| what does cerfazolin kill? |
|
Definition
|
|
Term
| what does cerfuroxime kill? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
aerobic G- that includes pseudomonus |
|
|
Term
|
Definition
|
|
Term
|
Definition
broadest antimicrobial spectrum
|
|
|
Term
| name two beta lactamase inhibitors |
|
Definition
Clavulanic acid
sulbactam |
|
|
Term
|
Definition
| combo of trimethoprim and sulfamethoxazole used in uti |
|
|
Term
|
Definition
| clavulanic acid and ammoxicillin |
|
|
Term
| What does vancomycin kill |
|
Definition
G+
used for systemic of enteric because not absorbed well, and Clostridium enterocolitis.
also only drug available for multiply resistant enterococcus and MRSA |
|
|
Term
| what are vancomycin side effects |
|
Definition
| toxic, kidneys and hearing |
|
|
Term
|
Definition
| acts like vancomycin with longer half life |
|
|
Term
| what is Cycloserine and what does it kill |
|
Definition
D alanine analog inhibits wall synthesis
tb very toxic |
|
|
Term
| What does bacitracin kill |
|
Definition
|
|
Term
| What does polymyxins kill |
|
Definition
|
|
Term
| What does daptomycin kill |
|
Definition
|
|
