Shared Flashcard Set

Details

CYP 3A4/5
Drugs to consider CYP3A4/5 interaction
24
Medical
Post-Graduate
01/15/2021

Additional Medical Flashcards

 


 

Cards

Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Cyclosporin

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Tacrolimus

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Everolimus

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Amiodarone

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Statins

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Colchicine

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Zolpidem

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Diltiazem

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Mirtazapine

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Quetiapine

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

TKI's

Definition
Substrate
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Carbamazepine

Definition
Inducer
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Phenytoin

Definition
Inducer
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Barbituates

Definition
Inducer
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Modafanil

Definition
Inducer
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Efavirenz

Definition
Inducer
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Azole Anti-Fungals

Definition
Inhibitor
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Macrolide Antibiotics (Clarithromycin, erythromycin)

Definition
Inhibitor
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Protease Inhibitor Anti-Virals

  • Ritonavir
  • Indinavir
  • Talapravir
Definition
Inhibitor
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Grapefruit Juice

Definition
Inhibitor
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Diltiazem

Definition
Inhibitor
Term

CYP 34A/5 substrate, inducer, inhibitor?

 

Verapamil

Definition
Inhibitor
Term
What is the effect of a CYP 3A4/5 Inducer on a substrate?
Definition
Decrease in substrate drug level concentration
Term
What is the effect of a CYP 3A4/5 Inhibitor on a substrate?
Definition
Increase in substrate drug concentration
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