Shared Flashcard Set

Details

CYP 2D6
Drugs that are important to know as CYP2D6 interactions
22
Medical
Post-Graduate
01/16/2021

Additional Medical Flashcards

 


 

Cards

Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Codeine

Definition
Metabolism (activation)
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Tamoxifen

Definition
Metabolism (activation)
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Tramadol

Definition
Metabolism (activation)
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Amitriptyline

Definition
Elimination
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Clozapine

Definition
Elimination
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Flecainide

Definition
Elimination
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Haloperidol

Definition
Elimination
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Nortriptyline

Definition
Elimination
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Risperidone

Definition
Elimination
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Bupropion

Definition
Strong inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Fluoxetine

Definition
Strong inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Paroxetine

Definition
Strong inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Quinidine

Definition
Strong inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Abiraterone

Definition
Moderate inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Cinacalcet

Definition
Moderate inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Darunavir

Definition
Moderate inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Duloxetine

Definition
Moderate inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Mirabegron

Definition
Moderate inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Perhexiline

Definition
Moderate inhibitor
Term

CYP2D6 required for metabolism, elimination, strong inhibitor, or moderate inhibitor?

 

Terbinafine (systemic)

Definition
Moderate inhibitor
Term
What effect do CYP2D6 inhibitors have on drugs that require CYP2D6 for metabolism?
Definition
Decrease efficacy of metabolism-dependent drug
Term
What effect do CYP2D6 inhibitors have on drugs that require CYP2D6 for elimination?
Definition
Increase plasma levels of the elimination-dependent drugs
Supporting users have an ad free experience!