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Comparative Vertebrate Anatomy Final (study other sets too)
Ch. 18-21 and Ch 13-14
206
Biology
Undergraduate 4
04/20/2013

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Term
Air has a higher oxygen content than water, but water must be in...
Definition
Solution to dissolve into the blood
Term
Respiratory surfaces in tetrapods must be...
Definition
moist at all times
Term
Water loss from moist respiratory surfaces...
Definition
Increases the risk of desiccation on land
Term
In tetrapods, respiratory surfaces are confined to...
Definition
The inside of the body, like lungs
Term
A surfactant...
Definition
Decreases the surface tension of water
Term
What does buccal mean?
Definition
Pertaining to the mouth
Term
Describe how a buccal pump works in amphibians.
Definition
The nares and glottis coordinate opening and closing of the mouth.
1. Nares open, the glottis is closed
2. The glottis opens and old air exits through the nares while the animal swallows new air
3. Nares close
4. Nares open and the glottis closes; start the cycle over
Term
There is not much mixing of oxygenated (+O2) blood and deoxygenated (-O2) in amphibians because...
Definition
They have a buccal pump, which is also used for calling mates
Term
Amphibians have secondarily lost their lungs. What does this imply?
Definition
They must live in a moist environment because respiration occurs across the skin surface
Term
What is a gharial on crocodiles and why is it important?
Definition
It is a bulge of ejaculatory tissue on the nose of males that makes them more attractive to females
Term
Tetrapods have evolved these two well defined structures for respiratory purposes.
Definition
A larynx and a trachea
Term
If only a simple lung is present, what does that mean about the organism?
Definition
It has a lower activity level
Term
Reptiliamorpha mechanics: An aspiration pump which...
Definition
Uses long muscles in the thoracic cavity to move air in and out
Term
Non-avian reptiles use aspiration pumps and even more, crocodiles and alligators use...
Definition
A hepatic piston for respiration
Term
Trace the path of air through a human system.
Definition
Air enters the nostrils, passes through the nasopharynx, the oral pharynx, through the glottis and into the trachea. Then it enters the right and left bronchi, which branches and rebranches into bronchioles, each of which terminates in a cluster of alveoli which are in the lungs and covered in dense capillary networks. The lungs are continuously ventilated by the diaphragm. The entire tract is lined by epithelial and mucous cells.
Term
How is O2 dissolved in mammalian systems?
Definition
In water through the aveolial cells and through 2 layers of tissue
Term
Describe the modified aspiration pump that mammals have.
Definition
They have parietal and visceral pleura that slide past each other to expand the lung. They are tightly held together like wet microscope slides
Term
What does the diaphragm do when mammals breath?
Definition
-at rest, the diaphragm is relaxed
-diaphragm contracts and the thoracic cavity volume increases [inhale]
-diaphragm relaxes, the thoracic cavity volume decreases [exhale]
Term
What is a buccal pump involved in?
Definition
Lung ventilation powered by cranial musculature alone (passive exhalation)- seen in fish; some lizards have a secondarily derived buccal pump
Term
What is an expiration pump involved in?
Definition
Active exhalation powered by axial muscles (buccal pump is retained for inhalation)- seen in tetrapods
Term
What is an aspiration pump involved in?
Definition
Inhalation powered by axial muscles (amniotes)
Term
What is circulation and what is its primary function?
Definition
Circulation is the movement of fluids throughout the body; it functions in transport of wastes out of the body
Term
Blood picks up O2 and releases CO2...
Definition
In the lungs
Term
Nutrients are transported from the intestines to...
Definition
The rest of the body
Term
Urea is transported in blood to...
Definition
The kidneys
Term
The circulatory system also transports things like...
Definition
hormones and immune cells
Term
Mammals with high activity levels also have...
Definition
The most complex body plans
Term
Every circulatory system requires three basic elements. What are they?
Definition
A pump, tubes, and fuild
Term
What is endocardium (also called endothelium)?
Definition
The epithelium lining the inner surface of the heart
Term
What is myocardium?
Definition
The cardiac muscle lining most of the heart walls
Term
What is visceral pericardium?
Definition
The epithelium lining the outer surface of the heart
Term
In a mammalian heart: The artia _____, the ventricles __________, the pulmonary circuit___________, and the systemic circuit _____________.
Definition
1. receive blood from the heart
2. pump blood away from the heart
3. carries (-O2) blood from the lungs
4. carries the blood from the body
Term
What is the purpose of valves in the heart?
Definition
They prevent the back flow of blood between the heart chambers
Term
What is the function of gap junctions?
Definition
They span 2 plasma membranes and hold the 2 cells together
Term
Cells in the heart are interlocked to...
Definition
Increase surface area
Term
The sinoartrail (SA) node is known as the...
Definition
Pacemaker of the heart
Term
Describe the 4 steps involved in controlling heart rhythm.
Definition
1. Pacemaker generates the wave of signals to contract
2. Signals are delayed at the AV node.
3. Signals pass through the heart apex.
4. Signals spread throughout ventricles
Term
Why are Purkinje fibers (nerve fibers) only found in birds and mammals?
Definition
These organisms are endothermic and have an increased activity level, so they need the most efficient heart contractions and these fibers help strengthen the heart contractions
Term
What is the tunica intima?
Definition
The interior epithelial layer
Term
What is the tunica externa?
Definition
The connective tissue that provides elasticity so shape can be changed
Term
What is the tunica media?
Definition
The smooth muscle layer in the middle of veins and arteries. In veins, it doesn't let blood flow backward. In arteries, it helps regulate the flow
Term
Blood flows toward the heart in veins with (-O2) blood except in two cases. Name and describe them.
Definition
They are umbilical and pulmonary veins; there is a major drop in pressure when blood reaches capillary beds
Term
Plasma is 55% of the volume of human blood and contains...
Definition
90% water, the salts, nutrients, wastes and gases of the blood, and antibodies and clotting agents; (Platelets cause fibrinogen)
Term
The binding of heme groups to red blood cells...
Definition
Allows )2 to be transported
Term
What are the three types of blood cells?
Definition
Red blood cells, white blood cells, and platelets
Term
What type of stem cells can possibly become red blood cells?
Definition
Hematopoietic stem cells
Term
These 3 organs generate new cells in anamniotes.
Definition
The liver kidneys, and spleen
Term
In amniotes, the liver kidneys, and spleen serve to...
Definition
Filter the blood; marrow makes new cells
Term
What are the 4 components of a heart of a spiny dog fish (Squalus)?
Definition
1. sinus venosus which receives blood
2. the 2 atrium which pump blood forward into the ventricle
3. The ventricle, which is the primary pumping chamber
4. The conus arteriosus- where the pressure of blood drops
Term
A heart in a fish is a single circuit. Describe it.
Definition
The heart sends (+O2) blood to the gills and then to the body.
Term
If bony fish lungs are present...
Definition
They deliver (+O2) blood back to the systemic circuit rather than through a separate pulmonary circuit; mixing of blood is okay because lung respiration is minimal
Term
This type of septa divides the heart into partial or complete left and right chambers.
Definition
Inter-artrial
Term
In most lungfish, blood from the lungs enters the left atrium and blood from the body (via the sinus venosus) enters...
Definition
The right atrium
Term
Lungfish separate blood in the ventricle by having a...
Definition
Inter-ventricular septa
Term
The spiral valve in the conus arteriosus of fish and frogs...
Definition
Directs blood either toward the aortic arches and toward the lungs or gills (-O2), or to the body (+O2)
Term
Amphibians have a ventricular trabeculae to...
Definition
Separate blood in the ventricle-the trabeculae are shelves/ridges extending from the walls of the ventricle
Term
Amniote hearts have a double circuit which implies...
Definition
(+O2) blood is sent to the body via the systemic circuit and (-O2) blood is carried to the lungs via the pulmonary circuit
Term
Turtles, snakes,and lizards have an incompletely divided heart meaning...
Definition
Their heart has three chambers but it can function like a 4 chambered heart
Term
The sinus venosus is seen...
Definition
-As the pacemaker of basal vertebrates
-As the right atrium in birds
-As the SA node in mamammals
Term
The two ventricles are only present and completely separated in...
Definition
Birds,crocodiles, and mammals
Term
How many aortic arches do hagfish and lampreys have going through the gills?
Definition
8 or more
Term
Gnathostomes have a primitive pattern of...
Definition
6 aortic arches passing through the gills and connecting to the ventral and dorsal aortae (all 6 form in embryos and some are lost in development)
Term
Sharks retain 5 of the 6 aortic arches. Describe them.
Definition
Arch 1-lost during ontogeny; the 1st efferent becomes the efferent spiracular
Arch 2-loses the respiratory function and drains the 1st collecting loop into the internal carotid
Term
Actinopterygians and aortic arches
Definition
Arch 1 and 2 are lost; Arch 3-6 are present and pass through the gills
Term
Lungfish~aortic arches
Definition
Arch 1 is lost, Functions of arches 2-4 are changed
Term
Amphibian (frog) aortic arch development is described by...
Definition
Arch 1 and 2 being lost, Arch 3 becomes the internal carotid which irrigates (takes blood) to the brain
The external carotid originates from the base of the brain and carries blood to the jaw region
Arch 4 is the systemic arch
Arch 5 is lost
Arch 6 becomes a vessel
Term
Reptiles and their aortic arches...
Definition
Arch 1 and 2 are lost
Arch 3 becomes the internal carotid
Arch 4 is the systemic arch
Arch 5 is lost
Arch 6 is the base of the pulmonary artery
Term
Aortic arches of BIRDS
Definition
Arch 1 and 2 are lost
Arch 3 becomes the internal carotid
Arch 4 is the right aortic arch [no left aortic arches are present)
Arch 5 is lost
Arch 6 is the pulmonary artery
Term
Aortic arch development in mammals
Definition
Arch 1 and 2 are lost
Arch 3 becomes the internal carotid
Arch 4 is the systemic arch
Arch 5 is lost
Arch 6 is the pulmonary artery
*the left aortic arch is the main aortic arch, but the right arches are present as well!!!
Term
The fluid of the lymphatic system is called...
Definition
Lymph
Term
Vessels of the lymphatic system have veins that drain back into...
Definition
The circulatory system at the subclavian veins
Term
What do lymph nodes do?
Definition
They filter lymph and preform immune functions like attacking viruses and bacteria
Term
The fluid and proteins blood loses through diffusion across capillary walls are returned via...
Definition
The lymphatic system
Term
What is osmoregulation?
Definition
The management of solute and water concentration
Term
Osmoregulation is achieved by...
Definition
Indirect regulation of solutes and the movement of water; interstitial fluid via the blood helps too
Term
What is the primary organ involved and its function in osmoregulation?
Definition
The organ is the kidney and it serves to filter metabolic wastes and balance the ion concentration
Term
Ions and wastes dissolve in water so...
Definition
The water balance is maintained in osmoregulation
Term
There are 3 forms of nitrogenous wastes. What are they in detail?
Definition
*Ammonia-toxic, used mostly by aquatic animals
*Urea-has a metabolic cost, used by mammals, amphibians, sharks, and some bony fish
*Uric acid-high metabolic cost, used by birds, reptiles, insects, and snails
Term
What is the first key function of an excretory system?
Definition
Filtration-water and solutes are forces by blood pressure across the selectively permeable membranes of a cluster of capillaries and into the excretory tubule. The tubule collects filtrate and large items stay in the blood.
Term
What is the second key function of an excretory system?
Definition
Reabsorption- the transport of epithelium selectively reclaims valuable substances (glucose and some salts). This influences concentration, thus it influences osmosis.
Term
What is the third key function of an excretory system?
Definition
Secretion- blood to filtrate; other substances (toxins, excess ions) are extracted and added to the tubule.
Term
What is the fourth key function of an excretory system?
Definition
Excretion-the filtrate leaves the system and the body
Term
(The mammalian excretory system anatomy)
Efferent arterioles are smaller to...
Definition
Increase pressure-they split up into Peritubular capillaries for maintaining gradients and reabsorption
Term
(The mammalian excretory system anatomy)
What is the function of the proximal tubule?
Definition
Regain water, balance pH, keep drugs, nutrients and NaCl in the system
Term
(The mammalian excretory system anatomy)
The vasa recta is concurrent exchanger which...
Definition
Maintains high salt gradients to passively save water
Term
(The mammalian excretory system anatomy)
The antidiuretic hormone [ADH] increases...
Definition
Permeability of the collecting ducts
Term
(The mammalian excretory system anatomy)
-Loop of Henle component
*The descending loop of Henle is...
Definition
Permeable to water but not salts
Term
(The mammalian excretory system anatomy)
-Loop of Henle component
*The ascending loop of Henle is...
Definition
Permeable to salts but not water; this helps establish the gradient for the descending loop of Henle
Term
(The mammalian excretory system anatomy)
-Loop of Henle component
*Distal Tubule
Definition
Secretion and reabsorption
Term
A nephron is the funtional unit of a kidney and...
Definition
It is the site of filtration, reabsorption, secretion, and excretion
Term
Collecting ducts join tubes together to...
Definition
Send products to the pelvic region for secretion
Term
Secretion only occurs via...
Definition
Active transport
Term
What percentage of all products from the collecting tubes is excreted as urine in mammals?
Definition
Only 1%
Term
Kidney development
Definition
-Arise from the nephric ridge/intermediate mesoderm
-Classified types by which portion is functional in the adult
Term
Pronephros (a type of kidney)
Definition
-Anterior in the organism; drain into the duct
-Seen in embryonic and larval hagfish, lamprey, many fish, amphibians
-ONLY hagfish retain a functional one as an adult
Term
Mesonephros (a type of kidney)
Definition
-The middle portion of the nephric ridge
-functions in the embryo and larvae of ALL vertebrates
-NOT functional in adult amniotes
-Mesonephric tubules: epididymis and ductus deferens in males
Term
-Mesonephros and more caudal metanephros
-This kidney is found in most anamniote vertebrates (lampreys, sharks, actinopterygians, and amphibians)
Definition
Opisthonephros (a type of kidney)
Term
-Most caudal portion of the nephric ridge
-The functional kidney of adult amniotes
-The cranial mesonephric tubules and archinephric duct carry sperm in males; no urinary function; lost in females
-Metanephros is drained by the ureters, which are newly evolved structures
Definition
Metanephros (a type of kidney)
Term
Ureters drain directly into...
Definition
The cloaca of some reptiles;
*birds lose the bladder as an adaptation for flight
*smakes lose the bladder because of their body form
*mammals, lizards,turtles and some amphibians store urine in the bladder
Term
Advanced opisthonephros have greater...
Definition
segmentation so organisms can be terrestrial
Term
Metanephros allow organisms to be even more terrestrial because...
Definition
The duct is retained but the function is retained
Term
The ten important stages in the development of aortic arches
[This denotes the first organisms to show this character]
Definition
1) Dorsal and ventral aortae in adults and embryos
2)8+ aortic arches [lampreys]
3)6 aortic arches during development
4)Collector arterial loops with pre and posttrematic vessels [Sharks]
5)1st and 2nd aortic arches lost or modified [Actinopterygians]
6)Pulmonary artery and vein and embryonic ducts arteriosus [Dipnoi]
7)Inter-atrial septum fully developed
8) Carotids develop from the third aortic arch and parts of the dorsal and ventral aortae [crocs and birds]
9) 4th Right arch= systemic arch [birds]
10) 4th aortic arch (left) =systemic arch [mammals]
Term
Osmoregulation in freshwater teleosts like carp
* is the main point
Definition
*lose ions; gain water
-Some water enters the mouth with food
-As water moves over gills, ammonia and water are lost while salts are actively taken up
-Urine is hyposmotic to blood and copious; some urea and ammonia are lost
Term
Osmoregulation in saltwater teleosts like cod
* is the main point
Definition
*lose water; gain ions
-Fish drinks water and as it passes the gills, ammonia and water are lost and Na+/Cl- are actively excreted
-Urine is hyposmotic to blood, but not so copious. It has ammonia, some urea, and divalent ions.
Term
Osmoregulation in sharks
* is the main point
Definition
*Gain water
-Water and salt enter the mouth with food
-At the gills, water is absorbed and there's a net loss of urea (back transport maintains a high blood level)
-Urine is hyposmotic to blood and copious; it contains some urea
-The digitiform gland balances salts
Term
* Evaporative water loss is key
-concentration of urine is high
-birds, some lizards, and turtles have salt-excreting glands to excrete salt through their nostrils
-mammals have a loop of Henle
Definition
Osmoregulation by tetrapods- broad overview
Term
Osmoregulation of a frog on land
Definition
-evaporative water loss through skin
-Urine is hypotonic to blood
-Some water is reabsorbed in the bladder and urea is lost
Term
-Water and active salt uptake occurs through the skin
Definition
Osmoregulation of a frog in water
Term
Osmoregulation of a lizard and its relatives
Definition
-Urine is nearly isotonic to blood and contains uric acid
-Water reabsorption occurs in the cloaca, intestine, and bladder
Term
-Evaporative water loss by panting in thermoregulation
-Urine is isotonic or slightly hypertonic to blood
-Urine is primarily uric acid
-Water reabsorption occurs in the intestine and the cloaca
Definition
Osmoregulation of a bird
Term
Osmoregulation of mammals
Definition
-Evaporative water loss by panting in thermoregulation and sweat glands in most animals
-Urine is hypertonic which is made possible by the kidney countercurrent multiplier system
-Urine contains urea
Term
Amphibians are susceptible to evaporative water loss because of...
Definition
Their thin skin and cutaneous respiration
Term
Amphibians have independent evolutionary events of...
Definition
*Secreting lipids and waxes as part of a wiping behavior to look shiny
*A change in posture due to their water reabsorption patch near the cloaca that absorbs water from the ground (up to 70-80% of water uptake sometimes)
*Some have a special bladder for water storage
Term
Additional independent evolutionary events of amphibians...
Definition
*Specialized skin cells to reduce the heat load by reflecting UV rays
*Cocoons for skin shedding events~they can stay under the mud for a few months
*Estivation- slowing down body processes and entering a burrow~they do this to avoid bad environments (ex. drought)
Term
Reptiles have thick, keratinized skin to...
Definition
Avoid water loss; some have salt- secreting glands
Term
Environmental challenges and solutions for freshwater creatures
Definition
1. Problem:Excess water uptake; must excrete water *Solution: Waste excreted as cheap ammonia
2. Problem: Ammonia is toxic *Solution: water used as a solvent (gills are the primary excretory organ)
-Additional costs-must actively transport solutes for retention
-Aquatic amphibians don;t use ammonia
Term
Environmental challenges and solutions for saltwater creatures
Definition
1. Problem: Excessive water loss (must conserve water)
2. Problem 2: Excessive salt uptake (must excrete salts)
*Solution 1: Become isosmotic (hagfish, marine teleosts) - lose gglomerulus to decrease water loss
*Solution 2: Become hyperosmotic (some elasmos)-retain urea (somewhat costly), minimally toxic because water is a solvent-urea (mammals) requires less water excretion-increase water uptake~cost=retain glomerulus (increased metabolism)-excrete water
*Solution 3: Develop special salt excretion glands (some elasmos, teleosts)-have a rectal gland and salt glands on gills
Term
Environmental challenges and solutions for terrestrial creatures
Definition
Challenge: dry environment, both water and salts are rare and must be retained
*Possible solution: return secondarily to water~this introduces earlier problems
*Solution 1: Excrete nitrogen as NH4, urea or uric acid~balance the costs and benefits
*Solution 2:Reduce glomerulus to save on the cost of filtering (arid reptiles and anurans)
*Solution 3: Solute recovery-develop loop of Henle-MAMMALS
*Solution 4: Salt glands (seen in desert and marine animals)
Term
Arid reptiles have 3 options when it comes to balancing water and salts. Name and describe them.
Definition
1. NH4 is cheap but toxic-would give animal a high H2O concentration
2. Urea-intermediate cost, low toxicity
3. Uric acid- high cost, not toxic, but low H2O concentration
Term
Sex reversal in sequential hermaphrodites
Definition
-gonads can change during animal's life
-seen in 5 orders of teleosts
-asexual reproduction is possible
-no group is ever without a female
Term
Which animals engage in external fertilization?
Definition
Frogs, fish, some salamanders
Term
Which animals engage in internal fertilization?
Definition
A few frogs, some fish, no salamanders, but all other animals
Term
Describe genotypic sex determination using humans as an example.
Definition
-Humans have heterogameteic males (XY)
-The SRY gene on Y chromosome codes for testosterone production and the Mullerian-inhibiting substance
-Male development suppresses female development (birds, mammals, snakes, some lizards)
Term
What is an example of environmental sex determination?
Definition
Sea turtles; their sex is determined by the nest temperature in the middle of the nesting season~NO sex chromosomes
>30 deg. Celsius =Females; <25 deg Celsius =males; in between= a mixture
Term
Steps 1-3 of follicle development in a human female
Definition
1. Of the 2 million eggs females are born with, only 400 are ovulated
2. Eggs in the primordial follicles, which are located around the outside of the ovary, multiply and form layer of granulosa cells around the egg
3.Surrounding layers of connective tissue contribute to the theca, which makes up the wall of the follicle
Term
Steps 4-6 of follicle development in a human female
Definition
4. The follicle protects and transfers nutrients to the egg; it also has an endocrine gland that secretes female hormones
5. As the follicle develops, a follicular liquor accumulates in spaces among the granulosa cells
6. The mature, or Graafian, follicle may be 10+mm in diameter and it bulges outward on the ovary surface, secreting estrogen
Term
Steps 7-9 of follicle development in a human female
Definition
7. The follicle pops off, starts meiosis 2, and pauses until sperm comes to activate it (this is when the ovum ovulates)
8. The corpus luteum releases progesterone in case of fertilization
9. If no sperm come to meet the egg, the cycle starts over
Term
The reproductive tracts of female anamniotes have less association with... and their oviducts are not...
Definition
kidney ducts; homologous to other vertebrates
Term
If a mammalian female gets pregnant in a place other than her oviducts, it is called...
Definition
An ectopic pregnancies
Term
What is unique about marsupial reproductive anatomy?
Definition
Females have a left and right vagina, and males have a forked penis
Term
The outer chorion, the chorioallantoic placenta, and the allantois all form...
Definition
The placenta of Eutherian (mammals like humans)
Term
Some squamates have a placenta, but it differs from humans in...
Definition
Development and attachment
Term
There is less of an exchange of nutrients, the yolk sac is not isolated but the allantois is, there is a short embryonic stage so the mother can abort the offspring in bad environmental conditions but these creatures are still species rich
Definition
This describes marsupial pregnancy.
Term
Immunological rejection is seen between...
Definition
Marsupial offspring and their mothers
Term
The offspring is within a shell membrane and then a placenta for the last 2/3 of their life in the pouch. Why?
Definition
This is because the marsupial mother does not recognize the DNA from the father and automatically rejects it.
Term
Reproductive ducts in non-mammalian males include the testes and the...
Definition
Archenephric duct, which is consistent across taxa and delivers sperm to the cloaca
Term
Describe the basics of mammalian male anatomy.
Definition
Testes are external during reproductive season and internal otherwise (except in humans); the sperm is stored in the epididymis; the prostate gland is responsible for raising the pH of the sperm/semen
Term
Nerve cells stimulate smooth muscles to make nitrous oxide, which is produced by the vascular endothelium. What does this cause to happen?
Definition
Human male erection
Term
The peripheral nervous system is made up of 2 components. What are they?
Definition
The sensory input and the motor output
Term
What type of cells do not undergo active cell division?
Definition
Nervous cells
Term
The central nervous system is made up of cell bodies called...
Definition
Nuclei
Term
The peripheral nervous system is made up of cell bodies called...
Definition
Ganglia
Term
A neurotransmitter affects _______ across the membrane.
Definition
Charge
Term
WITHOUT a receptor, what happens when a neurotransmitter is released from a vesicle across a synaptic cleft?
Definition
NOTHING
Term
Outside the cell, sodium concentrations are ____ and potassium concentrations are ____.
Definition
High; low
Term
What does decremental mean?
Definition
Slowly declining
Term
Describe the process of saltatory conduction of myelinated axons.
Definition
-There is a sodium inflow at a node which generates action potential. (It is slow but nondecremental)
-Sodium diffuses along the inside of the axolemma to the next node. (This is fast and decremental)
-Excitation of voltage-regulated gates will generate the next action potential at the next node.
Term
What does saltation mean?
Definition
Jumping
Term
This is the name for the autoimmune disorder where axons are demylinated. The schwann cells have been attacked.
Definition
Multiple sclerosis
Term
Where do full strength action potentials occur along an axon?
Definition
At the nodes of Ranvier
Term
The functioning of an ACh, or acetylcholine,synapse has four steps. What are they?
Definition
Step 1: An action potential arrives and depolarizes the synaptic knob.
Step 2: Extracellualr calcium enters the synaptic cleft triggering the exocytosis of ACh.
Step 3: ACh binds to receptors and depolarizes the postsynaptic membrane.
Step 4: ACh is removed by AChE, or acetylcholinesterase.
Term
What is the most important thing about the axon hillock?
Definition
The sum of all the stimuli it receives must be greater than -55mV to make an action potential occur.
Term
Name 3 common neurotransmitters and their functions.
Definition
1. Norepinephrine in the brain: responsible for excitatory action potentials in postsynaptic cells
2. Dopamine in the central nervous system: prevents overstimulation of neurons (example=cocaine users) and if it is inhibited, muscle tone is negatively affected
3. Serotonin in the central nervous system: drugs like prozac inhibit the re-uptake of this
Term
Neuroganglia are 30-50 times more numerous than neurons and serve to...
Definition
Support and protect neurons
Term
What are the 3 types of neuroganglia found in the central nervous system?
Definition
-Ependymal cells, Astrocytes, and Microglia
Term
What are Ependymal cells?
Definition
The ependymal epithelium that makes up the cerebrospinal fluid; They are the barrier between the outside world and the sensitive contents inside the cells
Term
What are Astrocytes?
Definition
These cells are for structural support. They have perivascular feet that cover capillaries to prevent diffusion, thus forming a blood brain barrier. They also function in tissue repairs and ion balances.
Term
What are Microglia?
Definition
Cells that digest waste products, such as other cells; sometimes called macrophages
Term
The central nervous system and the peripheral nervous system both have neuroganglia called...that function in...
Definition
Oligodendrocytes; axon myelination and framework; they are the 'white matter' in the central nervous system
Term
Neurons works via...
Definition
Ion gradients (sodium/potassium) or electric potentials
Term
Describe how an action potential happens.
Definition
At rest, the concentration of potassium INSIDE the cell is high and the concentration of sodium OUTSIDE of the cell is high. Once the threshold value of -55mV is reached, polarity is reversed and there is a wave of depolarization.
Term
What is propagation?
Definition
The movement of an action potential down an axon
Term
Schwann cells of the central nervous system and glial cells of the peripheral nervous system both arise from...
Definition
The neural crest
Term
Neurotransmitters bind for about _____ and must be blocked for the process of cessation to stop.
Definition
One millisecond
Term
What are the 3 methods of cessation of propagation?
Definition
1. Diffusion: release the neurotransmitter to the extracellular fluid and use astrocytes or enzymes to reabsorb/ return it
2. Reuptake via endocytosis and breakdown
3. Degredation or breakdown in the synaptic cleft
Term
A single neuron can have thousands of synapses. In fact the greater the number of synapses a neuron has...
Definition
The more processing ability the neuron has
Term
Name the two kinds of postsynaptic potentials.
Definition
Excitatory and inhibatory
Term
What happens if there is a single excitatory postsynaptic potential?
Definition
The cell is depolarized by ~0.5mV and the action potential is ready to go
Term
What happens is there is an inhibatory postsynaptic potential?
Definition
A larger depolarization is required for the action potential to fire.
Term
A nerve is a collection of...
Definition
Neurons
Term
What is the central bundle of nerves with several branches called?
Definition
The spinal cord
Term
Spinal nerves are derived from...
Definition
ectoderm--> neural crest--> neuroblasts --> neural tube
Term
What are the two pathways between the PNS and the CNS?
Definition
Somatic and Autonomic (Visceral)
Term
What are the two subdivisions of the autonomic nervous system?
Definition
The parasympathetic division and the sympathetic division
Term
The brain has both ____ and ____ matter.
Definition
Gray, white
Term
This part of the brain is divided into 4 zones. It is shaped like a butterfly.
Definition
The gray matter of the brain
Term
What are the 4 zones of the gray matter of the brain?
Definition
1. Somatic sensory
2. Visceral sensory
3. Somatic motor
4. Visceral motor
Term
The gray matter of the brain is made up of ______ axons.
Definition
Unmyelinated
Term
Myelinated axons are the only thing found in what part of the brain?
Definition
The white matter
Term
What region of the spinal cord allows communication between the cord and the brain?
Definition
The white matter or myelinated axons
Term
The white matter of the brain has fibers that run in how many directions?
Definition
Three; ascending, descending, reflexes
Term
Ascending fibers of white matter...
Definition
Head up to higher centers (sensory inputs)
Term
Descending fibers of white matter...
Definition
Head down to the spinal cord from the brain or from a higher to lower region of the cord (motor outputs)
Term
The hypothalamus is the...
Definition
Switchboard of the brain that sends and receives signals
Term
What is the difference between innate and conditioned reflexes?
Definition
Innate reflexes are things we just know how to do (like moving a hand off a hot iron) and conditioned reflexes are learned reflexes (like catching a ball)
Term
There are 2 types of neuron arcs. What are they and what is an example of each one?
Definition
A three-neuron reflex arc (has a sensory neuron, a motor neuron, and an interneuron); A two-neuron reflex arc (has a motor neuron and a sensory neuron)
Term
What are commissures?
Definition
Neuronal tracts that cross the midline of the body and signal intersegmental reflexes (like catching yourself with your opposite foot when you trip over something)
Term
Spinal nerves develop in a ___________ pattern
Definition
Segmental
Term
There are 4 types of plexuses that form from hypaxial differentiation. What are the 4 types?
Definition
-Cervical
-Lumbrosacral
-Coccygeal
-Branchial
Term
This system is called the rest and digest system. It is also responsible for thoraco-lumbar flow. The pre-ganglionic fiber is farther away from the CNS. The post-ganglionic fiber is shorter than in the other system.
Definition
The parasympathetic nervous system
Term
The sympatheic nervous system
Definition
-Responsible for cranio-sacral flow
-Ganglia is closer to the CNS
-It is known as the flight and fight system.
Term
Th two systems of the autonomic nervous system differ in...
Definition
Pre- and post-ganglionic neuron length
Term
No post-ganaglionic fibers are...
Definition
myelinated in the parasympathetic or the sympathetic nervous system
Term
The parasympathetic and the sympathetic post-ganglionic fibers release different...
Definition
Neurotransmitters; parasympathetic nervous system releases ACh and the sympathetic nervous system releases norepinephrine
Term
The brain forms from the _______ end of the neural tube while the spinal cord develops from the ______ end of the neural tube.
Definition
Anterior, posterior
Term
The initial 3 vesicles of the brain are...
Definition
1. The prosencephalon- the forebrain
2. The mesencephalon- the midbrain
3. The rhombencephalon- the hindbrain
Term
What are the 2 divisions of the prosencephalon and what are their functions?
Definition
-Telencephalon~smell, memory storage, intelligence
-Diencephalon~ vision, pineal gland (circadian rhythms), relay center, temperature and sleep
Term
The mesencephalon, or midbrain, functions in...
Definition
Relaying messages between the fore- and hindbrain, and processing data from eyes and ears
Term
*The metaencephalon~made up of the cerebellum (coordination of complex muscular movements and balance) and the pons~runs fiber tracts between cerebrum and cerebellum in mammals
*Myelencehpalon- includes the medulla oblongata (reflex center for involuntary activities- respiratory, cardiovascular, gastrointestinal)
Definition
These are the components of the rhombencephalon and their functions
Term
The midbrain and the cervical flexures develop and cause...
Definition
the telencephalon and the diencephalon to bend toward the hind brain
Term
Space limitations cause the cerebral hemispheres to grow...
Definition
Posteriorly and laterally over the rest of the brain
Term
What are gyri?
Definition
They are the parts of the brain that bulge out
Term
Growth of the cerebral hemispheres results in the formation of folds and creases called...
Definition
Sulci that increase the surface area of the cerebellum and allow more neurons to pack into the space
Term
What are the four main centers of the brain seen in mammals?
Definition
*The primary motor cortex
*The primary sensory cortex
*The primary auditory cortex
*The occipital lobe (primary visual cortex)
Term
What are the three unifying themes of this course?
Definition
1. Body sizes and shapes
2. Lifestyles
3. Ecologies
Term
Brain evolution does not necessarily follow...
Definition
Phylogenies of vertebrate evolution
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