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osmotic MOA: hydrophilic chemical that filters through glomerulus I: increased intracranial pressure, acute renal failure, drug toxicity, or trauma SE: hypo/hypernatremia, dehydration |
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carbonic anhydrase inhibitor at the proximal tubule MOA: H+ stays in the lumen and then Na+ doesn't get reabsorbed SE: metabolic acidosis, aplastic anemia CI: sulfa allergy |
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thiazide I: HTN, CHF, hypercalciruria MOA: inhibits Na/Cl cotransporter of distal convoluted tubule so decreased Na+ reabsorption SE: hypokalemia sulfa allergy |
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MOA: inhibits cotransport of Na/K/2Cl in ascending loop of Henle I: edema, CHF, hypercalcemia, hyperkalemia esp in renal insufficient pts SEL ototoxic, hyperuricemia, hypokalemia, hypomagnesemia, hypocalcemia |
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loop diuretic MORE ototoxic |
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k+ sparing MOA: block Na/K antiport in collecting tubule SE: hyperkalemia, leg cramps, hyperuricemia |
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K+ sparing MOA: steroid that antagnoizes aldosterone receptor I: secondary hyperaldosteronism, diuretic, CHF SE: gynecomastia, menstural irregularities |
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acetazolamide furosemide torasemide hydrochlorothiazide NOT ethacrynic acid and K+ sparing |
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