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Situation in which a pre-mRNA can be processed in more than one way to produce different mRNA molecules encoding different polypeptides. |
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A complex of DNA and proteins that makes up chromosomes. |
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Asexual reproduction in which the offspring are genetically identical to the parent. |
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Differential gene expression |
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Definition
Expression of different subsets of the genome in different cell types in multicellular organisms. |
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A collection on a slide of a very large number of different DNA fragments, each of which acts as a probe to monitor the presence and expression of a large number of genes or transcripts simultaneously. |
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A cis-acting DNA regulatory element that can activate transcription even at a great distance upstream or downstream from the promoter. |
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Refers to heritable changes in gene expression that are not due to changes in DNA sequences. |
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A portion of the transcribed region of a gene that is included in the mature mRNA molecule that exits the nucleus. |
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Idea that all of the cells in a multicellular organism contain the same genetic information. |
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Detection of a specific RNA of interest in place within an embryo, whole organism, organ, or tissue. |
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A portion of the transcribed region of a gene that is removed from the transcript before it exits the nucleus as a mature mRNA. |
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A stable membrane filter to which RNA from a particular tissue or developmental stage is bound. |
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The primary transcripts of genes that exist unprocessed in the nucleus. |
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The basic unit of chromatin organization, consisting of a short DNA segment wrapped around a core of histone proteins. |
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Definition
Sequences in the near-upstream region of a gene to which RNA polymerase binds to bring about transcription. |
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A gene whose product is easy to detect and measure that is used to assay the function of a promoter element or enhancer. |
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Definition
Phenomenon in which expression of a single gene is silenced by introduction of a double-stranded RNA sequence corresponding to part of the mRNA. |
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Definition
Detection of a particular rare RNA in a complex sample by amplification using a combination of reverse transcriptase and polymerase chain reaction. |
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A cis-acting DNA regulatory element that represses transcription even at a great distance upstream or downstream from the promoter. |
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Definition
A protein that binds to a promoter region or enhancer/silencer to activate or repress transcription of a particular gene. |
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