Term
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Definition
subdural hemorrhage, bacterial meningitis |
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Term
beta amyloid and tau proteins |
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Definition
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Term
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Definition
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Term
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Definition
bacterial and viral meningitis |
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Term
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Definition
lymphoblastic leukemia, AIDS, meningitis |
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Term
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Definition
mild subarachnoid/subdural hemorrhage |
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Term
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Definition
MS, tumors (any demyelinating conditions), guillain-barre |
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Term
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Definition
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Term
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Definition
CSF leakage (otorrhea, rhinorrhea) |
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Term
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Definition
indicative of MS (indicates de novo IgG production @ sites of demyelination in CSF) |
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Term
when is persistently high lactate a bad sign? |
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Definition
after head trauma. associated with poor prognosis |
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Term
adenosine deaminase (ADA) |
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Definition
>15u/l indicates TB meningitis |
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Term
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Definition
elevated in hydrocephalus, cerebral infarction, neoplasia, subarachnoid hemorrhage, head trauma, tumor |
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Term
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Definition
increases 6 hours after ischemic or anoxic injury |
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Term
what is lactate dehydrogenase level useful for? |
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Definition
distinguishing traumatic tap from intracranial hemorrhage (will be normal in traumatic tap bc rbc membrane still intact); elevated LD after resucitation following hypoxic brain injury indicates poor prognosis |
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Term
what is the classical test for endotoxin? |
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Definition
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Term
what is the test of choice for spirochetal meningitis? |
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Definition
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Term
nonreactive serum FTA-ABS? |
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Definition
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Term
reactive serum FTA-ABS with nonreactive CSF FTA-ABS? |
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Definition
strongly excludes neurosyphilis |
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Term
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Definition
dx of neurosyphilis likely |
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Term
reactive CSF FTA-ABS test |
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Definition
indicates neurosyphilis (but could be false+, which is why VRDL is the test of choice) |
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Term
what does CSF look like for HIV patients? |
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Definition
lymphocytic pleocytosis, elevated IgG indexes, oligoclonal bands |
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Term
how do we dx fungal meningitis? |
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Definition
1. latex agglutination (twice as sensitive as india ink for crypto) 2. culture for fungus (need large vol of csf) |
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Term
what do we use acridine orange stain for? |
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Definition
to distinguish ameba from leukocytes (primary amebic meningoencephalitis) |
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