Term
ALBUTEROL GENERIC NAME/TRADE NAME |
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Definition
GENERIC: Albuterol TRADE: Airet, Proventil, Repetabs,Respirol, Ventolin, Volmax, Combivent (with Ipratroprium) |
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Term
ALBUTEROL CHEMICAL/THERAPEUTIC CLASS |
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Definition
Sympathomimetic amine; Beta 2 adrenergic agonist. Antiasthmatic, bronchodilator |
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Term
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Definition
Selective Beta 2 adrenergic agonist with minimal number of side effects. Prompt bronchodilation, duration of +/- 5 hours. |
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Term
ALBUTEROL PHARMACOKINETICS |
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Definition
Onset 5-15 minutes. Peak 1 - 1 1/2 hours. Duration 4-6 hours. T 1/2 = 2 1/2 - 4 hours |
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Term
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Definition
1. Bronchial asthma. 2. Reversible bronchospasm associated with chronic bronchitis and emphysema. 3. Anaphylactic respiratory distress. |
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Term
ALBUTEROL CONTRAINDICATIONS |
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Definition
1. Hypertension - SBP > 180 2. Tachycardia - HR > 140 adult; >180 peds 3. Severe cardiac disease (chest pain that could be MI 4. Hypersensitivity |
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Term
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Definition
1. Hyperthyroidism 2. Diabetes mellitus 3. Convulsive disorders |
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Term
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Definition
CNS - dizziness, headache stimulation, tremors CV - chest pain, dysrhythmias, hypertension, palpitations, tachycardia GI - nausea, vomiting |
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Term
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Definition
Small volume nebulizer with O2 6-10lpm. Adult - 2.5mg 3.0mL in 0.083% solution by mouthpiece or face mask Q10 min x 4 max Peds - same by mask or blow-by |
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Term
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Definition
Unit dose vials containing 2.5ml in 3mL |
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Term
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Definition
1. Possibility of side effects increases with other sympathetic agonists. 2. Beta blockers may blunt the effect of albuterol 3. Albuterol also comes in metered-dose inhalers delivering 90mcg per inhalation 4. Overdose can cause bronchial constriction and possibly death. |
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Term
ASPIRIN GENERIC/TRADE NAME |
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Definition
Aspirin Bayer, Bufferin, Ecotrin |
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Term
ASPIRIN CHEMICAL/THERAPEUTIC CLASS |
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Definition
Salicylate deriviative Antiplatelet agent |
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Term
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Definition
Aspirin blocks the formation of the substance thromoboxane Alpha2, which causes platelets to aggregate and ateries to constrict. Reduces mortality associated with MI. Reduces rate on nonfatal reinfarction and nonfatal stroke. |
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Term
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Definition
Chest pain suggestive of acute MI. |
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Term
ASPIRIN CONTRAINDICATIONS |
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Definition
1. Hypersensitivity to aspirin, NSAIDS and tartrazine (FDC yellow dye #5) 2. Bleeding disorders including GI hemorrhage and hemophilia 3. Hemorrhagic states. |
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Term
ASPIRIN PRECAUTIONS/PREGNANCY CATEGORY |
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Definition
Children or teenagers with flu-like symptoms, which may be associated with development of Reye's Syndrome. Pregnancy category C. |
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Term
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Definition
GI - GI bleeding heartburn, nausea HEME - prolonged bleeding time |
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Term
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Definition
When administered together, aspirin and anti-inflammatory agents may cause increased incidence of side effects and increased blood levels of both drugs. Administration with antacids may reduce drug level from decreased absorption. |
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Term
ASPIRIN ADMINISTRATION/SUPPLY/NOTES |
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Definition
Give four 81mg chewable tablets (324mg total dose) PO asap after onset of chest pain. 81mg low dose chewable tablets Must complete CSEMS local protocols to be authorized to administer |
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Term
DEXTROSE GENERIC/TRADE NAME |
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Definition
Dextrose. Glucose, Glutose, Insta-Glucose |
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Term
DEXTROSE CHEMICAL/THERAPEUTIC CLASS |
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Definition
Carbohydrate. Nutrient, caloric. |
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Term
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Definition
Supplies supplemental glucose in cases of hypoglycemia and restores blood sugar to normal (70-110mg/dL) |
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Term
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Definition
1. ALOC of unknown etiology (GCS = 12) 2. Hypoglycemia (<60mg/dL) by glucometer or clinical judgment 3. Status epilecticus 4. Oral hypoglycemic agent overdose 5. Neonatal resuscitation not responsive to ventilation and chest compressions. |
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Term
DEXTROSE CONTRAINDICATIONS |
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Definition
None for a patient with suspected hypoglycemia. |
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Term
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Definition
1. Use with caution in pts with increased intracranial pressure because may worsen cerebral edema 2. Localize venous irritaion may occur in smaller veins 3. Infiltration may cause tissue necrosis 4. Dextrose is only administered IV/IO |
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Term
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Definition
Tissue necrosis and phlebitis at the injection site. |
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Term
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Definition
Pt > 2 YO - Dextrose 50% 1g/kg up to 25g IV. Repeat once in 2 min if ALOC persists Pt < 2 YO - Dextrose 25% 1g/kg up to 25g IV. Repeat once in 2 min if ALOC persists. Neonate <28 days old - Dextrose 12.5% 1g/kg IV (8mL/kg) |
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Term
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Definition
Prefilled syringe containing 25 grams in 50mL (50% solution) |
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Term
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Definition
1. Establish free flowing IV of normal saline in large vein. Aspirate blood before and during administration of dextrose to ensure patency. |
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Term
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Definition
Prefilled syringe containing 25 grams in 50mL (50% solution) |
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Term
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Definition
Hypoglycemic states require immediate intervention. Prolonged can result in brain damage. |
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Term
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Definition
To make Dextrose 25%, dispel 25mL of solution from the pre-filled syringe and draw 25mL of normal saline back into the syringe. Dextrose 25% will contain 12.5g in 50ml. |
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Term
DIPHENHYDRAMINE GENERIC/TRADE |
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Definition
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Term
DIPHENHYDRAMINE CHEMICAL/THERAPEUTIC CLASS |
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Definition
Ethanolamine derivative Antihistamine, antianaphylactic agent |
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Term
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Definition
Antihistamin with anticholinergic and sedative side effects. Decreases the allergic response by blocking histamine and H1 receptor sites. |
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Term
DIPHENHYDRAMINE PHARMACOKINETICS |
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Definition
PO Peak 2 - 4 hours T1/2 2 - 8 hours IV = NA |
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Term
DIPHENHYDRAMINE INDICATIONS |
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Definition
1. Anaphylaxis, as adjunct to epinephrine 2. Severe vomiting & motion sickness 3. Treat extrapyramidal reactions caused by phenothiazines 4. Adjunct to haloperidol for combative patients secondary to acute psychotic episodes or alcohol intoxication |
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Term
DIPHENHYDRAMINE CONTRAINDICATIONS |
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Definition
1. Bronchial asthma 2. Nursing mothers 3. Children < 10kg. 4. Glaucoma 5. Hypersensitivity to drug or other antihistamines |
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Term
DIPHENHYDRAMINE PRECAUTIONS/PREGNANCY CLASS |
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Definition
Use with caution in patients with a history of hyperthyroidism, cardiovascular disease and hypertension. Pregnancy class B. |
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Term
DIPHENHYDRAMINE SIDE EFFECTS |
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Definition
CNS: dizziness, drowsiness, sedation, sleeplessness CV: headache, palpitations GI: dryness of mouth, nose and throat RESP: thickening of bronchial secretions, wheezing |
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Term
DIPHENHYDRAMINE INTERACTIONS |
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Definition
1. Has additive effects with alcohol and other CNS depressants 2. MAO inhibitors prolong and intensify anticholinergic (drying) effects of antihistamines. |
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Term
DIPHENHYDRAMINE ADMINISTRATION/SUPPLY |
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Definition
Adult - give 1mg/kg up to 50mg IM or slow IV push (25mg/min) Pediatric - give 1mg/kg up to 50mg IM or slow IV push (25 mg/min) Vial containing 50mg in 1ml. |
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Term
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Definition
The IV route is preferred for the patient in severe shock. If an IV cannot be readily established give via IM route, deep into large muscle mass. |
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Term
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Definition
The IV route is preferred for the patient in severe shock. If an IV cannot be readily established give via IM route, deep into large muscle mass. |
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Term
EPINEPHRINE 1:1000 GENERIC/TRADE NAMES |
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Definition
Epinephrine 1:1000 Adrenalin |
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Term
EPINEPHRINE 1:1000 CHEMICAL/THERAPEUTIC CLASS |
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Definition
Catecholamine Bronchodilator, vasopressor |
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Term
EPINEPHRINE 1:1000 ACTIONS 1 |
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Definition
Naturally occurring catacholamine. Acts directly on alpha and beta andrenergic receptors. It's effect is more profound on beta than alpha receptors. Effects on B1 andrenergic receptors include a positive chronotropic (increased HR) and positive inotropic (contractile force) effect. |
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Term
EPINEPHRINE 1:1000 ACTIONS 2 |
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Definition
The effects of epinephrine on the alpha andrenergic receptor sites include increased systemic vascular resistance. The effects on B and A receptors causes an increased BP. Also causes bronchodilation due to effects on B2 adrenergic receptors. |
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Term
EPINEPHRINE 1:1000 PHARMACOKINETICS |
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Definition
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Term
EPINEPHRINE 1:1000 INDICATIONS |
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Definition
1. Anaphylaxis 2. Bronchial asthma 3. Respiratory distress due to epiglottitis or croup. |
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Term
EPINEPHRINE 1:1000 CONTRAINDICATIONS |
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Definition
Epinephrine should be avoided in the following pts unless signs and symptoms are severe: 1. Hypertension SBP> 180 2. Tachycardia HR >140 adult, 180 child 3. Cardiovascular disease 4. Elderly age >55 5. Angle closure glaucoma |
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Term
EPINEPHRINE 1:1000 PRECAUTIONS/PREGNANCY CATEGORY |
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Definition
Precautions: 1. Hyperthyroidism 2. Diabetes mellitus |
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Term
EPINEPHRINE 1:1000 SIDE EFFECTS |
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Definition
CNS - anxiety, dizziness, restlessness, tremulousness, headache CV - anginal pain, dysrhythmias, hypertension, palpitations GI - nausea, vomiting SKIN - pallor |
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Term
EPINEPHRINE 1:1000 INTERACTIONS |
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Definition
Cyclic antidepressants and antihistamines may potentiate the effects of epinephrine. |
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Term
EPINEPHRINE 1:1000 ADMINISTRATION |
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Definition
Adult - give 0.3mg IM. Repeat in ten minutes if needed Peds - give 0.01mg/kg up to 0.3mg IM. Repeat in ten minutes PRN. |
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Term
EPINEPHRINE 1:1000 SUPPLY/NOTES |
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Definition
Ampule containing 1mg in 1ml. The IM route is preferred for the patient in severe shock. |
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Term
GLUCAGON GENERIC/TRADE NAMES |
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Definition
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Term
GLUCAGON CHEMICAL/THERAPEUTIC CLASS |
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Definition
Polypeptide hormone Antihypoglycemic |
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Term
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Definition
Protein secreted by alpha cells of the pancreas. When released, it causes the breakdown of glycogen stored in the liver to glucose. Inhibits synthesis of glycogen from glucose. Both cause in increase in circulating blood glucose. |
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Term
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Definition
A return to consciousness following the administration of glucagon take 5-20 minutes. Only effective if there are sufficient stores of glycogen in the liver. |
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Term
GLUCAGON PHARMACOKINETICS |
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Definition
Onset withing 15 minutes. T1/2 = 3 to 6 minutes. |
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Term
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Definition
When unable to obtain IV access and give dextrose AND: 1. ALOC of unknown etiology (GCS = 12) 2. Hypoglycemia based on glucometer or clinical judgment. 3. Status epilepticus 4. Oral hypoglycemic agent overdose. |
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Term
GLUCAGON PRECAUTTIONS/PREGNANCY CATEGORY |
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Definition
Glucagon in only effective if there are sufficient stores of glycogen in the liver. IV dextrose is the agent of choice. Pregnancy category C |
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Term
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Definition
CNS - dizziness, headache CV - hypotension GI - nausea, vomiting |
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Term
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Definition
Adult - 1mg IM Pediatric - 1mg IM |
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Term
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Definition
Must be reconstituted before administration. Supplied in rubber stoppered vials containing 1mg powder and 1ml of diluting solution. |
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Term
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Definition
Must complete local protocols class to use. May be given to reverse effects of beta blocker overdoses, usually 3 to 10 mg IV bolus followed by a 2 - 5 mg/h infusion. |
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Term
IPRATROPIUM GENTERIC/TRADE NAMES |
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Definition
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Term
IPRATROPIUM CHEMICAL/THERAPEUTIC CLASS |
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Definition
Quarternary ammonium compound. Bronchodilator |
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Term
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Definition
Anticholinergic bronchodilator related to atropine. Inhibits action of acetylcholine at receptor sites on bronchial smooth muscle, thus inhibiting parasympathetic stimulation and causing bronchodilation. Antisecretory properties locally. |
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Term
IPRATROPIUM PHARMACOKINETICS |
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Definition
Onset 5 to 15 minutes. Peak 1 to 2 hours. Duration 3 to 6 hours. |
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Term
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Definition
1. Bronnchoconstriction in COPD, including chronic bronchitis and emphysema as an adjunct to albuterol. 2. Bronchial asthma as an adjunct to albuterol. |
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Term
IPRATROPIUM CONTRAINDICATIONS |
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Definition
Hypersensitivity to the drug, or to atropine and its derivatives. |
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Term
IPRATROPIUM PRECAUTIONS/PREGNANCY CATEGORY |
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Definition
Use with caution in patients with narrow-angle glaucoma, prostatic hypertrophy or bladder-neck obstruction. Pregnancy category B |
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Term
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Definition
CNS - anxiety, dizziness, headache, nervousness CV - palpitations GI - nausea, vomiting EENT - blurred vision, dry mouth RESP - bronchospasm, cough |
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Term
IPRATROOPIUM ADMINISTRATION |
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Definition
Using small volume nebulizer, O2 6-10L/min. Adults and children 500mcg in 2.5mL mouthpiece, face mask or blow by. Do not repeat. |
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Term
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Definition
Unit dose vials containing 500mcg in 2.5ml. Give only one dose with the initial albuterol treatment. Do not use as stand alone drug. Not used for anaphylactic respiratory distress. |
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Term
NALOXONE GENERIC/TRADE NAME |
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Definition
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Term
NALOXONE CHEMICAL/THERAPEUTIC CLASS |
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Definition
Thebaine derivative Antidote, opiate |
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Term
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Definition
Chemically similar to opiates, but only antagonistic properties. Competes for opiate receptors in the brain. Displaces narcotic molecules from opiate receptors. Reverses respiratory depression from narcotic overdose. |
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Term
NALOXONE PHARMACOKINETICS |
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Definition
IV - Onset 2 minutes T1/2 4 minutes |
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Term
NALOXONE INDICATIONS/CONTRAINDICATIONS |
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Definition
1. Respiratory depression caused by narcotics. 2. Coma unknown etiology. Contra - hypersensitivity. |
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Term
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Definition
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Term
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Definition
Administer cautiously to pts who are know or suspected to be physically dependent on narcotics. Abrupt reversal can cause withdrawal-type effects. This includes newborns of dependent mothers. |
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Term
NALOXONE PREGNANCY CATEGORY |
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Definition
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Term
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Definition
CNS - seizures, tremulousness, withdrawal symptoms. CV - hypertension, hypotension, tachycardia, ventricular dsyrhythmia GI - nausea, vomiting |
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Term
NALOXONE ADMINISTRATION - ADULT/SUPPLY |
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Definition
Adult - 2mg IV at 0.4mg/min (5 in to push) IM - give two 0.8mg injections (1.6mg) in different muscles. If no response, contact medical control. Vial containing 4mg in 10mL. |
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Term
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Definition
Pediatric - IV - five 0.1mg/kg up to 2mg IV at 0.4mg/min IM - give 0.1mg/kg up to 1.6mg IM. If no response, call medical control. |
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Term
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Definition
1. Unless necessary, avoid insertion of advanced airway prior to administration of naloxone. 2. Administer by slow IV push (0.4mg/min.) 3. Reversal effects may be temporary, titrate to respiratory rate. 4. Common narcotics include codeine, Darvon, Demerol, Dilaudid, fentanyl, heroin, morphine, Nubain, paregoric, Percodan, Stadol, Talwin. |
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Term
NITROGLYCERIN GENERIC/TRADE NAMES |
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Definition
Nitroglycerin. Nitrolingual, Nitroquick Nitrostat, Nitr-bid, Nitrol |
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Term
NITROGLYCERIN CHEMICAL/THERAPEUTIC CLASS |
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Definition
Nitrate, organic. Antianginal, vasodilator |
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Term
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Definition
Rapid smooth muscle relaxant that causes vasodilation and to a lesser degree dilates the coronary arteries. This results in increased coronary blood flow and improved perfusion of the ischemic myocardium. |
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Term
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Definition
Vasodilation decreases preload and leads to decreased cardiac work, helping to reverse the effects of angina pectoris. |
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Term
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Definition
Decreased preload results in decreased pulmonary capillary hydrostatic pressure and reduction of fluid passing into the pulmonary interstitium and alveoli cardiogenic pulmonary edema. |
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Term
NITROGLYCERIN PHARMACOKINETICS |
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Definition
SL - Onset 1 to 3 minutes. Peak 5 minutes. Duratin at least 25 min. T1/2 2-3 min. TOP - Onset 15 to 60 min. Peak 30 to 120 min. Duration 2 to 12 hours. |
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Term
NITROGLYCERIN CONTRAINDICATIONS |
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Definition
1. Hypotension SBP < 100. 2. Bradycardia HR < 60. 3. Increased intracranial pressure (CVA, head injury). 4. Hypersensitivity. 5. Patient on Viagara or other anti-impotence agent. |
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Term
NITROGLYCERIN PRECAUTIONS 1 |
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Definition
1. Administer with extreme caution if at all to pts. with suspects inferior wall MI with possible right ventricular involvement because these patients require adequate RV preload. |
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Term
NITROGLYCERIN PRECAUTIONS 2 AND 3 |
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Definition
Pts taking routinely may develop tolerance and require an increased dose. Postural syncope sometimes occurs following administration and should be anticipated. Keep pt. supine. |
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Term
NITROGLYCERIN PRECAUTIONS 4 AND PREGNANCY CATEGORY |
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Definition
Careful clinical or hemodynamic monitoring must be used because of the possibility of hypotension and tachycardia. Pregnancy category C. |
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Term
NITROGLYCERIN SIDE EFFECTS |
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Definition
CNS: dizziness, headache, weakness CV: dysrhythmias, palpitations, postural hypotension, tachycardia GI: nausea, vomiting SKIN: diaphoresis, flushing, pallor, rash |
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Term
NITROGLYCERIN INTERACTIONS 1 AND 2 |
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Definition
1. Severe hypotension is possible in pts who have recently ingested alcohol. 2. Orthostatic hypotension is possible when used in conjunction with beta andrenergic antagonists. |
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Term
NITROGLYCERIN INTERACTIONS 3 |
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Definition
Administration contraindicated in pts who are using anti-impotence agents such as sildenafil since they have been known to hypotensive effects of organic nitrates. |
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Term
NITROGLYCERIN ADMINISTRATION |
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Definition
An IV or INT must be established prior to administering unless the patient has taken before without complications. |
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Term
NITROGLYCERIN SUBLINGUAL ADMINISTRATION |
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Definition
Chest pain - give 0.4mg SL. Repeat q 5 min up to 3 doses. Pulmonary edema (SBP>180) give 2 tablets 0.4mg SL. Repeat 2 tablets q 3 min PRN. Pulmonary edema (SBP 100-180) five 1 tablets 0.4mg SL. Repeat 1 tablet q 5 min PRN. Pediatric - not indicated. |
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Term
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Definition
1. Alternate the SL site when repeating dose. 2. May produce burning or tinging sensation when administered SL. This is not a reliable method to determine potency. |
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Term
NITROGLYCERIN TOPICAL DOSE |
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Definition
Chest pain - if pain persists after SL, apply 1 inch of paste. Pulmonary edema SBP > 180, apply 2 inches of paste. Pulmonary edema SBP 100-180 apply 1 inch of paste. Pediatric not indicated. |
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Term
NITROGLYCERIN TOPICAL NOTES |
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Definition
1. Apply paste to chest or upper arm. 2. Do not rub into skin. 3. If contraindications develop when paste is applied, remove the paste. 4. Wear gloves for application and removal of paste. |
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Term
NITROGLYCERIN SUPPLY AND NOTES |
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Definition
Tablet: Bottle containing 0.4mg (1/150 grain) tablets Paste: Packets containing 1 gr (1 inch) or tubes containing 30 to 60 grams. Keep in original container, tightly capped. |
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Term
ONDANSETRON GENERIC AND TRADE NAMES |
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Definition
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Term
ONDANSETRON CHEMICAL AND THERAPEUTIC CLASS |
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Definition
Carbazole derivative Antiemetic |
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Term
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Definition
Selective 5-HT3 antagonist which is an effective anti-nausea and anti-emetic with minimal side effects. Nausea and vomiting are strongly associated with serotonin receptors of the 5-HT3 type. Present peripherally on vagal nerve terminus and centrally in the chemoreceptor trigger zone of the area postrema. |
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Term
ONDANSETRON PHARMACOKINETICS/INDICATIONS |
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Definition
IV: peak immediate. IM: n/a 1. Severe vomiting or nausea 2. Vertigo |
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Term
ONDANSETRON CONTRAINDICATIONS/PRECAUTIONS/PREGNANCY CATEGORY |
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Definition
Contra: hypersensitivity. Pre: rarely, transient ECG changes including QT interval prolongation. Pregnancy cat B. |
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Term
NITROGLYCERIN SIDE EFFECTS |
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Definition
CNS: headache, lightheadedness, seizures CV: angina, bradycardia, syncope, tachycardia. EENT: blurred vision. GI; constipation, diarrhea. RESP: bronchospasm. SKIN: rash |
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Term
NITROGLYCERIN ADMINISTRATION/SUPPLY |
|
Definition
IV: give 0.1 mg/kg up to 4.0 over 2 to 5 min. May repeat once in 5 min if needed. IM: give 0.1 mg/kg up to 4 mg IM. Do not repeat. Vial containing 4mg in 2mL. |
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Term
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Definition
Dextrose, Glutose, Insta-Glucose |
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Term
|
Definition
Used to treat pts. with history of diabetess with ALOC and ability to swallow. Can reverse hypoglycemic condition. Time makes a critical difference. Comes in a tube of gel. |
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Term
ORAL GLUCOSE INDICATIONS/CONTRAINDICATIONS |
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Definition
Pt. with ALOC ad known history of diabetes controlled with medication. 1. Unresponsive. 2. Unable to swallow. |
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Term
ORAL GLUCOSE SIDE EFFECTS AND SUPPLY |
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Definition
None when given properly. May be aspirated without a gag reflex. Tube contains 15 grams. |
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Term
|
Definition
1. Assure signs and symptoms of AL with known history. 2. Assure pt. is conscious and can swallow and protect airway. 3. Administer between cheek and gum. Place on tongue depressor between cheek and gum. |
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