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CRPS
CBN III
23
Medical
Graduate
02/12/2011

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Cards

Term
what is complex regional pain syndrome/reflex sympathetic dystrophy?
Definition
a chronic disease most often resulting from trauma, characterized by pain disproportionate to the inciting cause and frequently not explained by conventional diagnostics - thus under-diagnosed/under-treated by the medical community.
Term
what is the hx of RSD/CPRS?
Definition
was called causalgia back in the civil war and usually was related to trauma.
Term
what are the s/s of RSD/CPRS?
Definition
pain (unique burning) and skin hypersensitivity, vasomotor skin changes, sweat disturbance/edema, motor disturbances, and various degrees of trophic change. often follows musculoskeletal trauma, sx or immobilization.
Term
what are the 2 types of CRPS?
Definition
CRPS 1 = RSD. CRPS 2 = causalgia (involves nerve injury). CRPS NOS (not otherwise specified) = partially meets criteria, better explained by other conditions.
Term
who does CRPS affect more?
Definition
women 30-50 y/o, usually following trauma. possibly related to hormones.
Term
what characterizes the pain due to CRPS?
Definition
the initial pain due to injury is sharp and proportional to the injury - but when the musculoskeletal damage is repaired, a different, disproportionate, continuing burning pain occurs. this pain is characterized as *allodynia (pain from a stimulus that does not normally provoke pain), *hyperalgesia (excessive sensitivity to pain), and *hyperesthesia (increased sensitivity to a sensory stimulation).
Term
what are the other clinical features of CRPS (other than pain)?
Definition
hx of edema, changes in skin blood flow, or abnormal sweating in the region of pain (*red, shiny swollen limbs*). decreased ROM and other motor dysfunction (weakness, tremor, dystonia, neglect), and exclusion of medical conditions that would otherwise account for the degree of pain and dysfunction. the pain is often unilateral. abnormal sweating, swelling, limited movement, weakness, tremor, dystonia, neglect, and abnormal hair/nail growth.
Term
what characterizes the CRPS/RSD diagnosis?
Definition
no other dx better explains the symptoms
Term
does CRPS/RSD spread?
Definition
yes, 95% of the time it moves horizontally or vertically (if it crosses over = worse prognosis). this can happen as late as 8 yrs later.
Term
what is in the ddx for CRPS/RSD?
Definition
DM and other small-fiber peripheral neuropathies, entrapment neuropathies, thoracic outlet syndrome, discogenic dz, cellulitis, vascular insufficiency, *lymphedema, costochondritis, brachial plexopathies, and *fibromyalgia.
Term
how is RSD/CPRS diagnosed?
Definition
x-ray, CT, MRI, triple phase bone scan, discogram, myelogram, arthogram, lab testing, EMG, SSEP (measure somatosensory components), QST-ANST (measures autonomic nerve function for vibration and sense), and *thermography (infrared, best diagnostic test for sympathetic dysfunction and RSD)*.
Term
how is RSD/CPRS treated?
Definition
goals: functional restoration, pain management, and psychological tx. requires physiotherapy, medical, psychological (all RSD pts are depressed) and family support.
Term
what diet and lifestyle alterations can help w/RSD?
Definition
anti-inflammatory diet, raw foods, smoking cessation, and home exercise
Term
what alternative therapies can help w/RSD?
Definition
reiki, manipulation/massage, acupuncture, and yoga/meditation.
Term
what vitamins help w/RSD/CRPS?
Definition
B-12/intrinsic factor
Term
what characterizes physical therapy for PSD/CRPS?
Definition
mobilization/movement asap, desensitization, and it is very important that the therapist have experience in this type of pt.
Term
what are the rx's for the 4 types of pain in CRPS?
Definition
muscle pain: muscle relaxants, inflammatory pain: NSAIDs/steroids. deep bone pain: analgesics. burning: neuroleptics.
Term
what are other medications which are used in CRPS/RSD?
Definition
antidepressants, anti-anxiety agents, antispasmodics, Ca++ channel blockers, antihypertensives, pamidronate, lenalidomide, mexilitine, capsaicin, DMSO, dextromethorphan, and amantadine
Term
does ketamine help w/CRPS?
Definition
under certain circumstances this IV is the **best drug available to give these pts their life back.
Term
what are other therapies used?
Definition
interventional pain management, sympathetic blocks, brachial plexus blocks, hospital based epidural infusions, spinal cord stimulators, intrathecal pumps, and prialt
Term
what is the risk with surgery in RSD pts?
Definition
high risk of spreading the disease. the worst is upper body, shoulder/breast sx. intra-operative ketamine can help prevent this.
Term
what underlying conditions need to be treated in RSD?
Definition
DM, hormonal imbalance, thyroid dysfunction, and cardiopulmonary issues (esp bradyarrhythmias)
Term
what are other symptoms of CRPS?
Definition
ha/, photophobia, otophobia, hoarseness, chest pain, cardiac arrhythmias, GI, GU, and immune system compromise.
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