Term
Chronic inflammatory condition involving the sacroiliac joints and the axial skeleton marked by bone formation at ligament and tendon attachments
Etiology Genetic predisposition with HLA-B27 antigen being present in >90% of patients
Remember that 5-7% of the normal white population are also HLA-B27+
3-4 times more common in males
Peak age between 25-35 years |
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Definition
| ANKYLOSING SPONDYLITIS [Marie-Strumpell disease] |
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Term
Definition Calcification of the intra-articular cartilage due to the deposition of calcium salts
Etiology Unknown |
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Definition
| CALCIUM PYROPHOSPHATE DEPOSITION DISEASE [Pseudogout] |
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Term
Definition Metabolic condition related to deposition of uric acid crystals in a joint;
inability to break down purines
Etiology Increased production or decreased excretion of uric acid |
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Definition
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Term
Definition An area of dense sclerotic bone in the ilium
Etiology Unknown |
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Definition
| OSTEITIS CONDENSANS ILII (aka Osteitis Triangularis aka Hyperostosis Triangularis) |
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Term
Definition Progressive degenerative of articular cartilage and hypertrophy of bone at the articular margins
Etiology Probably due to microtrauma; may have an inflammatory component
Worse in middle-aged and older females
More common in the weight-bearing joints: knee, hip, lumbar and cervical spine |
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Definition
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Term
Definition Common chronic scaly skin disorder characterized by an increase in the turnover of the cells of the skin [2 days instead of 14 days]
Etiology Genetic predisposition as it runs in families, not contagious, may be related to an autoimmune process which may be triggered by stress and physical trauma |
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Definition
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Term
Definition Joint, eye and urethral disease caused by a reaction to some infection
Etiology 50-80% of patients are HLA-B27 positive; may follow dysentery [Shigella dsysenteria] or a sexually transmitted infection [Chlamydia trachomatis]
More prominent in males |
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Definition
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Term
Definition Chronic inflammatory autoimmune disorder of joints
Etiology Familial tendency with HLA-DR4 and/or DR1
Middle aged females are more commonly affected |
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Definition
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Term
Definition Chronic connective tissue disorder characterized by diffuse systemic or localized sclerosis
Etiology Autoimmune disorder
F: M-3:1 ratio
Peak incidence: 50-60 years |
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Definition
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Term
Definition Multisystem chronic autoimmune Connective Tissue Disorder with periods of exacerbation and remission
Etiology Unknown cause of antibody production against cell nucleus and cytoplasmic structures; leading to inflammatory changes, leukocytosis and immune complex deposition in multiple organs systems; mainly in young women [7:1 Female to male ratio] with a peak incidence between 20 to 45 years |
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Definition
| SYSTEMIC LUPUS ERYTHEMATOSUS |
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