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‘inward, to cover’, is composed of skin, hair, oil and sweat glands, nails and sensory receptors |
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study of skin’, the medical specialty that deals with the diagnosis and treatment of integumentary system disorders |
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aka the integument or the cutaneous membrane is the largest organ of the body. |
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classification of stratified squamous epithelium with five types of cells |
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90% of cells arranged in 4-5 layers (strata) |
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a water repellant sealant |
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‘black cells’, 8% of epidermal cells, produce melanin, yellow- red or brown-black pigment that contributes to skin color and absorbs UV light. |
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arise from red bone marrow; they participate in immune responses |
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least numerous of epidermal cells, located in deepest layer of epidermis, contacts flattened portion of a sensory neuron known as a merkel (tactile) disc |
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undifferentiated stem cells |
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‘base’, deepest layer of epidermis, single row of cuboidal or columnar keratinocytes. Stem cells |
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‘thornlike’, 8-10 layers of many sided keratinocytes. |
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‘little grains’, 3-5 layers of flattened keratinocytes undergoing apoptosis |
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‘clear’, present only in thick skin, fingertips, palms and soles. 3- 5 layers of flattened, clear, dead keratinocytes |
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‘horn/horny’, 25-30 layers of flattened dead keratinocytes which shed from the apical layer and are replaced by cells of the deeper strata. |
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an abnormal thickening of the stratum corneum |
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as cells move from one epidermal layer to the next, they accumulate more keratin. |
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an excessive # keratinized cells shed from the skin of the scalp. |
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the second or deeper part of the skin, composed of strong connective tissue containing collagen and elastic fibers with great tensile strength and ability to stretch and recoil. |
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makes up 1/5th of the dermis and consists of areolar C.T. with thin collagen and fine elastic fibers. |
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‘nipples’, small, fingerlike structures that project into the undersurface of the dermis. Contains capillary loops, tactile receptors known as meissner corpuscles or corpuscles of touch and free nerve endings. |
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‘netlike’, attached to the subQ layer and consists of dense irregular connective tissue with fibroblasts, interlacing bundles of collagen and some coarse fibers, a few adipose cells, hair follicles, nerves and blood vessels. |
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stretch marks, visible as red or silvery white streaks on the skin surface. |
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a series of ridges and grooves that appear either as straight lines or a pattern of loops and whorls on the tips of fingers & toes, palms, and soles. |
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he study of the pattern of epidermal ridges |
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amount and type of melanin (yellow-red, brown-black) contributes to skin color |
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red color due to the oxygen carrying pigment in red blood cells |
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‘carrot’, is a yellow-orange pigment. |
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the inherited inability of an individual to produce melanin which is missing from the hair, eyes and skin. |
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the partial or complete loss of melanocytes from patches of skin produces irregular white spots. |
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a permanent coloration of the skin, in which a foreign pigment is deposited into the dermis with a needle. |
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the insertion of jewelry through an artificial opening. |
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Accessory structures of the skin |
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hair, skin glands, and nails- develop from the embryonic epidermis |
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aka pili is present on skin surfaces except the palms, the palmar surfaces of the fingers, the soles of the feet. |
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each hair is composed of columns of dead keratinized epidermal cells bonded together by extracellular proteins. |
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is the superficial portion of the hair, which projects avove the surface of the skin. |
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portion of the hair deep to the shaft that penetrates into the dermis and sometimes the subQ |
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surrounds the root of the hair, made up of the external root sheath and an internal root sheath |
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downward continuation of the epidermis |
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produced by the matrix & forms a tubular sheath between the external root sheath and the hair. |
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the dense dermis surrounding the hair |
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at the base of each hair follicle is an onion shaped structure |
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a nipple-shaped indentation which contains areolar C.T. and blood vessels |
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the site of cell division, cells arise from the stratum basale, produces new hairs when old hairs are shed. |
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a bundle of smooth muscle and attaches to the hair, pulls the hair shafts perpendicular to the skin. |
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dendrites of neurons sensitive to touch generate nerve impulses if their shafts are moved. |
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the partial or complete lack of hair |
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by 5th month of development, downy hairs cover the body of the fetus |
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long, coarse, heavily pigmented hairs replace the lanugo of the eyebrows, eyelashes and scalp. |
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‘peach fuzz’, replaces the lanugo of the rest of the body. |
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glands are epithelial cells that secret a substance. |
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‘greasy’, aka oil glands, are simple branched acinar glands that are mostly connected to hair follicles and secret sebum |
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‘sweat, bearing’, aka sweat glands which releases sweat directly onto the skin surface through pores. |
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‘secreting outwardly’, aka merocrine sweat glands, simple coiled tubular glands which are more common than apocrine glands. |
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sweat that evaporated from the skin before it is perceived as moisture |
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sweat that is excreted in larger amounts and is seen as moisture on the skin. |
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aka cold sweat, sweat released in response to an emotional stress. |
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‘separated from’, are simple coiled tubular glands found mainly in skin of the axilla, groin, areolae, and beards of adult males. |
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modified sweat glands in external ear which produce a waxy lubricating secretion, called cerumen or earwax |
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plates of tightly packed, hard dead, keratinized epidermal cells that form a clear, solid covering over the dorsal surfaces of the distal portions of the digits. |
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visible portion of the nail. |
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part of nail body that extends beyond distal end of digit. |
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portion of nail that is buried in a fold of skin. |
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whitish crescent-shaped area of the proximal end of the nail body with thickened epithelium underneath |
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‘below nail’, aka nail bed, a thickened region of stratum corneum which secures the nail to the fingertip. |
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‘above nail’, aka cuticle, a narrow band of epidermis that extends from and adheres to the margin of the nail wall |
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the proximal portion of the epithelium deep to the nail root where cells divide by mitosis to produce growth. |
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Thermoregulation • Blood Reservoir • Protection • Cutaneous Sensations • Excretion and Absorption • Synthesis of Vitamin D |
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wound may extend to dermis, includes abrasions and minor burns. Cells enlarge & migrate across the wound. |
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migration of epidermal cells stops completely when they come in contact with each other on all sides. |
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Injury extends to the dermis and subcutaneous layer, scar tissue is formed and there is some loss of normal function.1. Inflammatory phase • Inflammation: vascular & cellular response that helps eliminate microbes, foreign material, and dying tissue in preparation for repair. 2. Migratory phase: The clot becomes a scab. Epithelial cells migrate beneath the scab to bridge the wound. 3. Granulation tissue: The tissue filling in the wound • Proliferative phase: extensive regrowth of epithelial cells beneath scab. • Fibrosis: the process of scar tissue formation • Hypertrophic scar: scar remains within the boundaries of original wound • Keloid/cheloid scar: scar extends beyond boundaries into normal surround tissues 4. Maturation phase: the scab sloughs off when epidermis restored to normal thickness. |
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vascular & cellular response that helps eliminate microbes, foreign material, and dying tissue in preparation for repair. |
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The clot becomes a scab. Epithelial cells migrate beneath the scab to bridge the wound. |
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The tissue filling in the wound |
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extensive regrowth of epithelial cells beneath scab. • Fibrosis: the process of scar tissue formation |
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the process of scar tissue formation |
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scar remains within the boundaries of original wound |
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scar extends beyond boundaries into normal surround tissues |
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the scab sloughs off when epidermis restored to normal thickness. |
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