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Cronk Bone Tissue
Chapter 6
53
Biology
Undergraduate 1
05/06/2012

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Term
The skeletal system
Definition
includes the bones, their cartilages, ligaments and tendons
Term
Osteology
Definition
the study of bone structure and treatment of bone disorders
Term
Functions of Bone
Definition
Support
• Protection • Assistance in movement • Mineral homeostasis • Blood cell production
Term
Structure of bone
Definition
macroscopic parts of long bone
Term
Diaphysis
Definition
the body or shaft of a long bone
Term
Epiphyses
Definition
the proximal and distal ends of a long bone
Term
Metaphyses
Definition
The regions between the epiphysis and diaphysis.
Term
Epiphyseal plate
Definition
the growth zone of hyaline cartilage
Term
Epiphyseal line
Definition
the bony fusion of the growth zone
Term
Articular Cartilage
Definition
hyaline cartilage over the bone ends of freely movable
joints.
Term
Periosteum
Definition
Connective tissue that surrounds bone except for the articular
cartilage.
Term
Periosteum:Composed of two parts
Definition
a. outer fibrous layer b. inner osteogenic layer
Term
outer fibrous layer
Definition
dense irregular connective tissue
Term
inner osteogenic layer
Definition
cellular layer
Term
Medullary Cavity
Definition
hollow cylindrical space within the diaphysis
Term
Endosteum
Definition
thin membrane that lines the bone surface of the medullary
cavity.
Term
Extracellular matrix
Definition
composed of 25 % water, 25% collagen fibers and 50%
crystallized mineral salts.
Term
Calcification
Definition
The mineral salts crystallizing in a framework of collagen
fibers causing the extracellular matrix to harden.
Term
Four cell types in bone tissue
Definition
1. Osteogenic cells: unspecialized stem cells derived from mesenchyme. 2. Osteoblasts: Synthesize and secret collagen fibers and initiate
calcification 3. Osteocytes: mature bone cells function to maintain its daily metabolism 4. Osteoclasts: It functions in digesting the extracellular matrix and then
reabsorbing the digested product & releasing it to the blood.
Term
Osteogenic cells
Definition
unspecialized stem cells derived from mesenchyme.
Term
Osteoblasts
Definition
Synthesize and secret collagen fibers and initiate
calcification
Term
Osteocytes
Definition
mature bone cells function to maintain its daily metabolism
Term
Osteoclasts
Definition
It functions in digesting the extracellular matrix and then
reabsorbing the digested product & releasing it to the blood.
Term
Compact bone
Definition
found beneath the periosteum of all bones and makes up the
diaphysis of long bones.
Term
Perforating or V olkmann’ s canals
Definition
transverse canals penetrated by blood
vessels, lymph vessels and nerves.
Term
Central/Halversian canals
Definition
canals that run longitudinally through the bone.
Term
Concentric lamellae
Definition
rings of calcified extracellular matrix
Term
Lacunae
Definition
‘little lakes’, the small spaces between the lamellae
Term
Canaliculi
Definition
tiny channels filled with interstitial fluid that radiate in all directions
from the lacunae.
Term
Osteons/Haversian system
Definition
repeating structural units which consist of a central
canal with concentric lamellae arranged
Term
Lamellae
Definition
The areas
between the osteons that are fragments of older osteons
Term
Circumferential lamellae
Definition
encircle the bone beneath the periosteum or encircle
the medullary cavity.
Term
Spongy Bone Tissue
Definition
lamellae arranged in an irregular lattice of thin columns called trabeculae.
Term
SHAFT OF LONE BONES
Definition
Periosteal arteries & veins Nutrient artery & vein
Term
ENDS OF LONG BONES
Definition
Metaphyseal artery & veins Epiphyseal artery & vein
Term
BONE FORMATION
Definition
Embryonic skeleton: Involves replacement of preexisting connective tissue with bone, does not lead to any structural differences in bone.
Term
I. INTRAMEMBRANOUS OSSIFICATION
Definition
A. Development of ossification center B. Calcification C. Development of trabeculae
D. Development of the periosteum
Term
II. ENDOCHRONDRAL OSSIFICATION
Definition
A. Development of the cartilage model B. Growth of the cartilage model C. Development of the primary ossification center D. Development of the medullary cavity E. Develoment of the secondary ossification center F. Formation of the articular cartilage & epiphyseal plate
Term
longitudinal growth
Definition
lengthwise growth of bone at the epiphyseal plate
Term
Appositional growth
Definition
bone growth in thickness
Term
REMODELING OF BONE
Definition
The ongoing replacement of old bone tissue by new bone throughout life
Term
bone resorption
Definition
the breakdown of minerals and collagen fibers by osteoclasts
Term
bone deposition
Definition
the addition of minerals and collagen by osteoblasts
Term
BONE HEALTH
Definition
• estrogens close the epiphyseal growth places • Vitamin A stimulates activity of osteoblasts • Vitamin C is needed for synthesis of collagen • Vitamin D helps build bone by increasing the absorption of calcium from foods • Vitamins K and B12 are also needed for synthesis of bone proteins • Insulin like growth factors, liver & bone, hGH, T3, T4
Term
STEPS IN FRACTURE REPAIR
Definition
1. Formation of fracture hematoma 2. Fibrocartilaginous callus formation 3. Bony callus formation
4. Bone remodeling
Term
Open (compound) fracture
Definition
The broken ends of the bone protrude through the
skin
Term
Closed (simple) fracture
Definition
Does not break the skin
Term
Comminuted fracture
Definition
The bone is splintered, crushed, or broken into pieces
Term
Greenstick fracture
Definition
A partial fracture in which one side of the bone is broken
and the other side bends
Term
Impacted fracture
Definition
One end of the fractured bone is forcefully driven into
another
Term
Pott’s fracture
Definition
Fracture of the fibula, with injury of the tibial articulation
Term
Colles’ fracture
Definition
A fracture of the radius in which the distal fragment is
displaced
Term
Stress fracture
Definition
A series of microscopic fissures in bone
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