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What determines volatile agent potency? |
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Definition
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Which volatile agent has the least effect on BP? |
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Which agent has the least effect on SVR? |
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Which agent(s) has the least effect on Cardiac Output? |
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Term
Which agent(s) increase HR the most? The least? |
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Definition
Most=enflurane>iso/des, least = sevo |
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Term
Which agent most sensitizes the heart to catecholamine effects? |
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Definition
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Term
What law explains why liquids at lower temps are more soluble to gases? |
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What property determines the speed of onset of a volatile agent? |
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Definition
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Term
What is another name for the blood:gas solubility coefficient? |
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Definition
The Ostwald solubility coeffecient |
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Term
Give the 4 volatile agent FA/FI ratios (% equilibrated after 30 minutes) |
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Definition
N20--99 Des--91 Sevo--85 Iso--73 |
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Term
Why does N20 come on faster than Des despite having a higher B:G coefficient? |
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Definition
Due to the concentration effect |
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Term
How long does it take N20 to equilibrate with all tissues in the body? |
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Definition
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What law accounts for N20 causing distention of gas cavities? |
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Definition
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What law accounts for the concentration effect of N20? |
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Definition
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Term
Explain the concentration effect |
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Definition
When switching from room air to N20, because N20 is much more blood soluble than N2, it enters the bloodstream from the alveoli much faster than N2 can leave the bloodstream into the alveoli. This causes the alveoli to shrink; the shrinking causes an increase in N20 concentration in the alveoli (same amount of agent, smaller space), and this leads to a equilibration time....HIGHER CONCENTRATIONS OF N20 EQUILIBRATE FASTER THAN LOWER CONCENTRATIONS |
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Term
Explain the concentration effect and second gas effect |
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Definition
When switching from room air to N20, because N20 is much more blood soluble than N2, it enters the bloodstream from the alveoli much faster than N2 can leave the bloodstream into the alveoli. This causes the alveoli to shrink; the shrinking causes an increase in N20 concentration in the alveoli (same amount of agent, smaller space), and this leads to a equilibration time....HIGHER CONCENTRATIONS OF N20 EQUILIBRATE FASTER THAN LOWER CONCENTRATIONS. This same principle explains the 2nd gas effect; the 2nd gas used will also have a higher concentration due to the shrinking of the alveoli |
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Term
How long does it take to double the volume of a closed gas space when 75% N20 is delivered? |
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Definition
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Term
What are the vapor pressures of Iso, Des, and Sevo? |
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Definition
Iso = 240 Des = 669 Sevo = 170 |
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