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Contrast Agents
N/A
44
Pharmacology
Professional
04/23/2013

Additional Pharmacology Flashcards

 


 

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Term
gas or radiopaque substance that is injected into the body, via catheter or swallowed, in order to image internal structures
Definition
contrast media/ agent
Term
contrast media is used because:
Definition
most organs and blood vessels have xray absorption similar to surrounding tissues
Term
an inert organic metallic salt of the chemical element barium
Definition
barium sulfate
Term
barium sulfate is used exlusively for radiography of the ___
Definition
GI tract, orally or rectally
Term
concentrated liquid suspension is
Definition
most commonly used
Term
contrast agents are supplied in form of a ___ for studies of pharynx and esophagus
Definition
oral paste
Term
allergies related to barium sulfate are almost never a problem, except if the preparations contain:
Definition
coloring or additives
Term
the principle problem with barium complications
Definition
its hygroscopic nature (can cause a bowel obstruction in patients with restricted bowel action)
Term
barium sulfate will be contra-indicated if ___ is suspected
Definition
rupture of GI tract (perforated ulcer/ ruptured appendix)
Term
iodinated media has an atomic number of __ and a mass of __, and is ___ compared to the composition of the body
Definition
53, 127, heavy
Term
most frequently used contrast agent other than barium
used when barium sulfate may be contra-indicated
Definition
water soluable (aqueous) iodinated compounds
Term
unlike barium, an advantage of compounds are that they:
Definition
absorb into the bloodstream
Term
a disadvantage of compounds are that they are more ___ and produce less ___
Definition
expensive, contrast
Term
do not use compounds if a ___ connecting ___ and ___ is suspected
Definition
fistula
esophagus, trachea
Term
the concentration required depends largely on ____
Definition
the degree to which it will be diluted by body fluids
Term
___ concentrations are needed for studies of the aorta
Definition
large
Term
greater concentrations have a ___ viscosity and osmolality and tend to be more ___
Definition
greater
toxic
Term
the number of particles in solution per kilogram of water
Definition
osmolality
Term
human blood is about ___ milliosmoles per kilogram
Definition
300
Term
the main reason for adverse reactions
Definition
injecting IV solution that exceeds the osmolality of human blood
Term
some contrast media molecules dissociate into ___ charged particles when placed into solution, resulting in ____ osmolality
Definition
2
higher
Term
media whose molecules disassociate are
Definition
ionic
Term
ethiodized oils are used in ____ and used to evaluate the clinical extent of lymphomas
Definition
lymphography
Term
oil based iodine media should be ____ in color when they are fresh
Definition
clear with pale amber or yellow
Term
___ have replaced oily media
Definition
aqueous iodine agents
Term
barium and iodine compounds provide ___ contrast because they absorb more radiation
Definition
positive
Term
air and gases produce __ contrast and dark shadows
Definition
negative
Term
when used in combination for double-contrast studies, the barium _____ and the air _____
Definition
coats the mucosal lining
fills the lumen
Term
ordinarily used to treat hypoglycemia, but used as a diagnostic aid in examinations of GI tract because it slows peristalsis
preferred over atropine
Definition
glucagon
Term
patients with food and airborne allergies are ___ as likely to have a reaction
Definition
twice
Term
asthma sufferers are ___ times as likely to have reaction
Definition
3
Term
severe reactions occur in _____ cases
Definition
1 out of 14,000
Term
fatal reactions occur in ___ cases
Definition
1 out of 40,000
Term
a mild reaction will occur within ___ minutes
Definition
30
Term
symptoms of a mild reactions
Definition
warm feeling
feeling flush
metallic taste in mouth
nausea, vomiting, coughing
Term
symptoms of intermediate reaction
Definition
erythema
hives
bronchospasms
vasovaga
Term
symptoms of a severe reaction
Definition
anaphylactic shock
cardiac arrest
seizures
hypotension
Term
most frequently used antihistamine
Definition
benadryl (diphenhydramine)
Term
adult dose of benadryl
Definition
25-50 mg orally
10-50 mg IV/IM
can be increased to 100 mg
Term
child dose of benadryl
Definition
12.5-25 mg orally
Term
maximum safe dose of benadryl in 24 hour period
Definition
400 mg IM or IV
Term
stimulates heart and sympathetic nervous system
administered subcutaneously or IM/IV
Definition
epinephrine/adrenaline
Term
medications used to treat allergic reactions
Definition
-benadryl
-short acting corticosteroids
-epinephrine
-methylprednisolone
Term
exams should be scheduled in this order:
Definition
1. all exams not requiring contrast
2. urinary tract
3. biliary system
4. lower GI
5. upper GI
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