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Connective Tissue
Set on Connective Tissue
16
Biology
Post-Graduate
12/04/2013

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Term
Fxns of connective tissue
Definition
Structural support, energy reserve, defense (Physical and home for phagocytic/immune cells), nutrient/waste exchange, repair of tissues
Term
What causes edema?
Definition
Lower venous pressure, increased vascular permeability, starvation
Term
Type 1 Collagen
Definition
Thick fibers not staining with silver and found in dermis, bone, tendon, organ capsules, and fibrocartilage... Synthesized by fibroblasts, osteoblasts, odontoblasts, and chondroblasts and fxn in strength and resistance to tensile forces.
Term
Type 2 Collagen
Definition
Thin fibrils and found in hyaline and elasic cartilage and made with chondroblasts and resistant to intermittent pressure.
Term
Type 3 Collagen
Definition
Thin fibers that associate with other fibers and are called reticular... Found in smotth muscle, endoneruium, arteries, liver, spleen, kidney, lung, and lymph nodes and are produced by smooth muscle cells, fibroblasts, schwann cells, and hepatocytes.... Flexible strength and often found in tissues where volume changes.
Term
Type 4 collagen
Definition
No fibrils or fibers and exists as procollagen peptides and is found in basal laminae and produced by epithelial cells, endothelial cells, muscle cells, and schwann cells.... Support attachement to underlying layers.
Term
Type 7 Collagen
Definition
Fibrils and found in basal laminae and produced by fibroblasts and anchor epithelium to underlying connective tissue...
Term
Collagen 9 and 11
Definition
No fibrils or fibers and bind to fibril forming collagens to stabilize them.... Found in cornea, tendons, cartilage.... Produced by chondroblasts, fibroblasts and important component in cartilage...
Term
Type 17 Collagen
Definition
Transmembrane protein part of hemidesmosomes and made in epithelial cells and anchor epithelium to connective tissue at desmosomes.
Term
What is Scurvy?
Definition
Brittle Collagen resulting from a loss of vitamin C which is required for hydroxylation of proline in the RER
Term
Systemic Sclerosis
Definition
Excessive Collagen Production causing organs to harden
Term
Ehlers Danlos Syndrome
Definition
Defects in collagen production for 3 and 4 types and results in increased elasticity, hyper joint mobility and fragile blood vessels.
Term
Two components of elastic fibers?
Definition
Elastin and microfibrils
Term
What causes Marfan syndrome?
Definition
Mutations in fibrillin 1 gene.
Term
Fibroglasts
Definition
Secrete and turn over most ECM components (INcluding Collagen)
Term
Macrophage
Definition
Phagocytose microorganisms
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