Term
| Type of embryonic connective tissue |
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Definition
| mesenchyme and mucous connective tissue |
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Term
| Types of connective tissue proper |
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Definition
| loose connective tissue and dense connective tissue- regular and irregular |
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Term
| Types of specialized connective tissue |
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Definition
| cartilage, bone, adipose tissue, blood, hemopoietic tissue, and lymphatic tissue |
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Term
| What's another name for loose connective tissue? |
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Definition
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Term
| What is the function and location of Type I collagen? |
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Definition
Provides resistance to force, tension, and stretch
Connective tissue of skin, bone, tendon ligaments, dentin, sclera, fascia, and organ capsules |
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Term
| What is the function and location of Type II collagen? |
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Definition
Provides resistance to intermittent pressure.
Cartilage (hyaline and elastic), notochord, and intervertebral disc |
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Term
| What is the function and location of Type III collagen? |
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Definition
Forms reticular fibers, arranged as a loose meshwork of thin fibers, provides a supportive scaffolding for specialized cells of various organs and blood vessels
Prominent in loose connective tissue and organs(uterus, liver, spleen, kidney, lung, etc.); smooth muscle; endoneurium; blood vessels; and fetal skin |
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Term
| What is the function and location of Type IV collagen? |
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Definition
Provides support and filtration barrier
Basal laminae of epithelia, kidney glomeruli, and lens capsule |
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Term
| Vit C deficiency can cause a problem in the formation of? |
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Definition
| collagen, you got scurvy son |
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Term
| What does Vit C help to do in collagen? |
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Definition
| It is required to add hydroxyl groups to the proline and lysine (part of the fiber) |
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Term
| What type of fibroblast makes collagen in cartilage? |
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Definition
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Term
| What type of fibroblast makes collagen in bone? |
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Definition
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Term
| What type of fibroblast makes collagen in blood vessels? |
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Definition
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Term
| What two proteins stimulate collagen synthesis? |
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Definition
transforming growth factor Beta (TGF-B)
platelet-derived growth factor (PDGF) |
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Term
| What type of steroid inhibits collagen synthesis? |
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Definition
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Term
| What enzyme degrades collagen after general wear and tear? |
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Definition
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Term
| Excessive collagen degradation is seen in? |
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Definition
| Rheumatoid arthritis and osteoporosis |
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Term
| Proteolytic degradation occurs outside the cells through the activities of these enzymes |
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Definition
| matrix metalloproteinases (MMPs) |
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Term
| this MMPs degrades Type I, II, III, and X collagens |
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Definition
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Term
| this MMPs degrades type IV collagen |
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Definition
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Term
| Can you see reticular fibers in H&E staining? |
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Definition
| No, need special stains like silver |
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Term
| Most likely place to find loose connective tissue? |
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Definition
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Term
| Give me some example examples of loose connective tissue. |
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Definition
| reticular tissue, elastic tissue, areolar tissue |
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Term
| Why does dense connective tissue take a long time to heal? |
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Definition
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Term
| What type of connective tissue is associated with basal lamina? |
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Definition
| reticular (collagen) fibers |
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