Term
| What is derived from the foxglove leaf? |
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Definition
| Digitalis and digitoxin. Used in CHF an dinhibits Na/K ATPase |
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Term
| what drug is derived from the vinca periwinkle plant and what does it treat? MOA? |
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Definition
| vinblastine and vincristine. treats a varity of leukemias by inhibiting microtubule formation and mitosis |
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Term
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Definition
extracts are flavonoids. They are anti-inflammatory, antioxidant, radical scavengers, and inhibit platelet aggregation.
Indicated in Alzheimers, vascular dementia, claudication, and tinnitus.
Bleeding can occur if used w/ warfarin |
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Term
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Definition
used in benign prostatic hypertension
inhibits 5-a-reductase, DHT binding to receptors, prostaglanding synthesis, and antagonizes a-1 receptors on prostatic capsule.
Gives false negative elevated PSA and interferes w/ iron absorption. |
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Term
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Definition
used for treatment of menopausal symptoms (sleep/mood disturbances and hot flashes)
estrogen receptor mediated effect.
Avoid in breast cancer pts. Hepatotoxicity risk.
SEs - GI distress, N/V. |
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Term
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Definition
treatment of mild to moderate depression, anxiety, or sleep disorders.
active agents are hyperforin, and hypercin.
inhibits MOA. Inhibits serotonin, dopamine, and NE reuptake. increase binding affinity for serotonin, benzodiazepine and muscarinic receptors.
Induces cP450. inactive OCP, simvastatin, PIs, and warfarin.
Contraindicated in antidepressants (esp SSRIs) |
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Term
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Definition
used for infectious disease symptom treatment.
Alkamide possesses anti-inflammatory COX1 and 2 effects.
SEs - allergic rxns, muscarinic inhibition, exacerbation of immune diseases (MG), inhibit cP450, and GI hemorrhage w/ NSAIDs |
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Term
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Definition
activation of monocytes. Stimulate TNF, IFN-y, and IL-2.
Improved vitality, immunity, cognition, and libido.
Restores homeostasis
SEs - insomnia, diarrhea, vaginal bleeding. Contraindicated in schizo. Inhibit platelets. increase QT. hypoglycemic effects. |
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Term
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Definition
intoxicating, sedative, local anesthetic, tranquilizing, anti-inflammatory, anti-microbial, anti-cancer. Potentiate GABA.
can cause serious hepatotoxicity, exacerbate parkinsons and cause kava dermopathy (psoriasis). w/ alcohol increases depressant effect. |
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Term
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Definition
inhibit superoxide radical formation
Anti-tumor effects
anti-inflammatory
weight loss promotion |
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Term
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Definition
seashell extract of amino-monosaccharides
A substrate for glycosominoglycan and proteoglycan synthesis.
Selective uptake by cartilage.
Inhibits proinflammatory cytokines, PGE, phagocytosis and lysozyme release |
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Term
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Definition
inhibit cholesterol synthesis, reduce blood pressure, inhibit platelet aggregation. Antimicrobial properties.
SEs - potentiates anti-coagulants, nausea, GI irratation |
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