Shared Flashcard Set

Details

Common Generic Drugs
Intro to pharmacology
66
Medical
1st Grade
08/01/2012

Additional Medical Flashcards

 


 

Cards

Term
Amoxicillin (AB)
Definition
cell wall synthesis inhibitor
URI - otitis media and sinusitis
UTI
Term
amoxicillin with clavulanate (AB)
Definition
bacterial cell wall synthesis inhibitor with beta lactamase inhibitor
URI - otitis media, sinusitis
UTI
diabetic foot ulcer
community acquired pneumonia
Term
azithromycin (AB)
Definition
macrolide antibiotic - binds to 50S ribosomal subunits of bacteria and suppress protein synthesis
upper and lower respiratory infections - sinusitis, community acquired pneumonia, acute eacervation of chronic bronchitis
atypical organisms - chlamydia, legionella and mycoplasma
Term
cephalexin (AB)
Definition
bacterial cell wall synthesis inhibitor - first generation cephalosporin
skin and soft tissue infections
UTI
Term
ciprofloxacin (AB)
Definition
interferes with DNA gyrase - for bacterial DNA synthesis
uti, synstemic infection with gram - organism
gonorrhea
Term
erythromycin (AB)
Definition
macrolide antibiotic that binds 50S ribosomal subunit to suppress protein synthesis
alternative for penicillin allergy for upper and lower resp. infection; skin and soft tissue infections
atypical organisms - chlamydia, legionella, mycoplasma
Term
levofloxacin (AB)
Definition
quinolone antibiotic; interferes with DNA gyrase necessary for DNA synthesis in bacteria
UTI, community acquired pneumonia, gonorrhea
Term
trimethoprim/sulfamethoxazole (AB)
Definition
antibiotic, sequential antimetabolite
UTI, upper respiratory infections (otitis, sinusitis) skin and soft tissue infections (community acquired MRSA)
Term
amlodipine
Definition
cardio
Ca channel antagonist
hypertension
Term
aspirin
Definition
cardio
acetylates platelet COX
inhibits prostaglandin synthase
antiplatelet (post MI, stroke), antinflammatory, antipyretic, analgesic
Term
atorvastatin
Definition
HMGCoA reductase inhibitor - blocks endogenous cholesterol synthesis
hypercholesterolemia, mixed hyperlipidemia (both cholesterol and triglyceride elevation)
cardiovascular drug
Term
candesartan
Definition
angiotensin receptor blocker
hypertension, CHF, left ventricular dysfunction
cardiovascular drug
Term
clopidogrel
Definition
selective, irreversible inhibitor of platelet activation by binding ADP dependent receptor on platelets
antiplatelets
cardiovascular drug
Term
diltiazem
Definition
Ca channel blocker
hypertension, angina, slow HR in supraventricular tachyarhythmias
cardiovascular drug
Term
fonsinopril
Definition
ACE inhibitor
CHF, hypertension
cardiovascular drug
Term
furosemide
Definition
blocks Na resorption from ascending limb of LOH
loop diuretic
cardiovascular drug
Term
gemfibrozil
Definition
increases lipoprotein lipase activity and decreases VLDL synthesis in the liver
hypertryglyceridemia
cardiovascular drug
Term
hydrochlorothiazide
Definition
blocks Na resorption from the proximal portion of the distal convoluted tubule
thiazide diuretic, hypertension
cardiovascular drug
Term
lisinopril
Definition
ACE inhibitor
hypertension, CHF
cardiovascular drug
Term
losartan
Definition
angiotensin 2 receptor antagonist
hypertension DMT2 nephropathy
cardiovascular drug
Term
metoprolol
Definition
selective B1 receptor antagonist
hypertension, angina, heart failure, post MI infarction
cardiovascular drug
Term
nifedipine
Definition
Ca channel antagonist
hypertension
cardiovascular drug
Term
propranolol
Definition
nonselective beta receptor antagonist
hypertension, angina, slow HR, migraine
cardiovascular drug
Term
simvastatin
Definition
HMGCoA reductase inhibitor
hypercholesterolemia, mixed hyperlipidemia (both cholesterol and triglyceride elevation)
cardiovascular drug
Term
terazosin
Definition
A1 receptor antagonist
hypertension, prostatic hypertrophy
cardiovascular drug
Term
verapamil
Definition
Ca channel antagonist
hypertension, angina, slow HR, supraventricular tachyarrhythmias
cardiovascular drug
Term
warfarin
Definition
vit K antagonist
anticoagulation
cardiovascular drug
Term
glyburide
Definition
endocrine
sulfonylurea antidiabetic agent - increases insulin secretion
DMT2
Term
insulin rapid/short acting lispro, glulisine regular
Definition
binds to endogenous insulin receptor
DMT1 or 2
endocrine
Term
insulin intermed/long acting NPH glargine determir
Definition
binds to endogenous insulin receptor
DMT1 or 2
endocrine
Term
metformin
Definition
biguanide antidiabetic
decreases hepatic glucose production and increases insulin sensitivity
DMT2
endocrine
Term
rosiglitazone
Definition
insulin sensitizer; improves insulin action in the presence of insulin
DMT2
endocrine
Term
sitagliptin
Definition
DPP4 inhibitor
DMT2
endocrine
Term
esomeprazole
Definition
GI
HK ATPase inhibitor
blocks gastric acid secretion
GERD, gastric or duodenal ulcer
Term
famotidine
Definition
GI
histamine 2 receptor blcoker, reduce gastric acidity
duodenal and gastric ulcers, GERD
Term
omeprazole
Definition
HK ATPase enzyme inhibitor, blocks gastric acid secretion
duodenal or gastric ulcer, GERD
GI
Term
ranitidine
Definition
histamine 2 receptor blocker; reduce gastric acidity
duodenal or gastric ulcer, GERD
GI
Term
albuterol
Definition
short acting selective B2 agonist
bronchodilator
pulm
Term
cetrizine
Definition
nonsedating antihistamine
allergic sinusitis/rhinitis
pulm
Term
fluticasone
Definition
inhibits phospholipase A2 and other multiple antinflammatory actions
inhaled anti-inflammatory agent for treatment of persistent asthma, nasal for allergic rhinitis
pulm
Term
ipratropium
Definition
cholinergic receptor antagonist
bronchodilator for COPD
pulm
Term
montelukast
Definition
leukotriene receptor antagonist
mild persistent asthma
pulm
Term
prednisone
Definition
inhibits phospholipase A2 and other multiple antiinflammatory actions
oral antiinflammatory agent for treatment of multiple inflammatory conditions
pulm
Term
salmeterol
Definition
long acting selective B2 receptor agonist
bronchodilator
pulm
Term
bupropion
Definition
norepi and dopamine reuptake inhibitor
antidepressant, smoking cessation
CNS
Term
desvenlafaxine
Definition
serotonin-NE reuptake inhibitor (SNRI)
depression, social anxiety disorder, generalized anxiety disorder, panic disorder
CNS
Term
diazepam
Definition
benzodiazepine receptor agonist
muscle relaxant, anxiolytic, anticonvulsant, alcohol withdrawal
CNS
Term
duloxetine
Definition
SNRI - serotonin-NE reuptake inhibitor
depression, pain
Term
escitalopram
Definition
selective serotonin reuptake inhibitor - SSRI
depression, generalized anxiety disorder
Term
gabapentin
Definition
anticonvulsant, neuropathy
Term
lorazepam
Definition
benzodiazepine receptor agonist
anxiolytic, anticonvulsant, antiemetic (combine with other agents), alcohol withdrawal
Term
paroxetine
Definition
SSRI
depression, social anxiety disorder, generalized anxiety disorder, panic disorder
Term
phenytoin
Definition
Na channel blocker, anitconvulsant
Term
sertraline
Definition
SSRI
depression OCD, panic attacks
Term
topiramate
Definition
Na channel blcoker, glutamate receptor blocker
anticonvulsant, neuropathy, migraine headaches
Term
celecoxib
Definition
pain/analgesics/antiinflammatory
selectove COX2 inhibitor
inhibits prostaglandin production
analgesic, antiinflammatory
Term
ibuprofen
Definition
inhibits cyclooxygenase; inhibits prostaglandin produciton
antiinflammatory, analgesic, antipyretic
Term
morphine
Definition
opiate agonist
analgesic
pain/analgesics/antiinflammatory
Term
naproxen
Definition
inhibits cyclooxygenase; inhibits prostaglandin production
pain/analgesics/antiinflammatory
Term
oxycodone (alone or with acetaminophen)
Definition
opiate agonist
analgesic
pain/analgesics/antiinflammatory
Term
oxycodone sustained release (alone or with acetaminophen)
Definition
opiate agonist
analgesic
Term
garlic
Definition
treatment of cholesterol
hold prior to surgery, prevents platelet aggregation, prolonged bleeding time
botanical
Term
ginkgo biloba
Definition
memory loss, claudication, sexual dysfunction
hold prior to surgery, prevents platelet aggregation
botanical
Term
isoflavones
Definition
menopausal symptoms
botanical
Term
St. John's Wort
Definition
depression
drug interactions decreases level of other important drugs - OCPs, anti HIV drugs, transplant immunosuppressants
botanical
Term
Kava
Definition
anxiety, insomnia, bipolar
associated with hepatotoxicity, liver failure
should be avoided!
botanical
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