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Coagulation
Coagulation
7
Medical
Graduate
06/09/2009

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Cards

Term
Test to order for suspected DVT or DIC
Definition
D-dimer
Term
Causes of a prolonged PT
Definition
Warfarin therapy
Vitamin K deficiency
Poor factor VII synthesis
Increased consumption of extrinsic factors
Term
Causes of a prolonged PTT
Definition
Use of heparin
Antiphospholipid antibody
Coagulation factor deficiency (hemophilia)
Term
PTT that is ~ 1.5-2.5 X normal value
Definition
Heparin therapy impact on PTT
Term
How many PT(INR) assays are performed annually worldwide
Definition
800 million
Term
D-dimer
Definition
small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. The concentration in a blood test can help diagnose thrombosis.
Term
ITP versus TTP?
Definition
ITP = decreased # of platelets resulting in bleeding, bruising, or extravasation from vessels.
TTP = spontaneous aggregation of platelets forming extensive thromboses throughout body
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