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Coagulation
Part 3
17
Nursing
Graduate
11/06/2014

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Term
BOTH INTRINSIC AND EXTRINSIC PATHWAYS RESULT IN ACTIVATION OF WHAT? WHAT DOES THE BEGIN?
Definition
FACTOR X WHICH BEGINS THE COMMON PATHWAY
Term
WHAT IS THE PRIMARU PATHWAY FOR COAGULATION AND WHAT IS THE SPEED FOR WHICH IT HAPPENS?
Definition
EXTRINSIC. HAPPENS A LITTLE FASTER
Term
WHILE PLT ACTIVATION IS INITIATED BY VWF, IT IS ALSO INITIATED BY WHAT FROM THE INJURED ENDOTHELIUM?
Definition
TISSUE FACTOR (III)
Term
IN AN EXTRINSIC PATHWAY TISSUE FACTOR FORMS A COMPLEX WITH WHAT FACTOR?
Definition
VII
Term
AFTER TISSUE FACTOR FORMS A COMPLEX WITH FACTOR VII IS ACTIVATES WHAT?
Definition
THIS ACTIVATES FACTOR VII (NOW VIIA)
Term
THE TISSUE FACTOR TF:VIIA COMPLEX ACTIVATES WHAT?
Definition
FACTOR IX AND FACTOR X (COMMON PATHWAY).
Term
WHAT IS THE SPEED IN WHICH THE INTRINSIC PATHWAY HAPPENS?
Definition
SLOWER
Term
IS THE INTRINSIC SYSTEM CONSIDERED AN AMPLIFICATION SYSTEM FOR THE EXTRINSIC PATHWAY?
Definition
YES
Term
ACTIVATION OF FACTOR WHAT BY FOREIGN SUBSTANCE OR OTHER FACTORS BEGINS THE CASCADE OF THE INTRINSIC PATHWAY.
Definition
XII.
Term
WHAT ION IS NEEDED IN ALMOST ALL OF THE INTRINSIC AND EXTRINSIC PATHWAYS?
Definition
CALCIUM
Term
FOR THE INTRINSIC PATHWAY DESCRIBE THE FACTORS THAT ARE INVOLVED.
Definition
XII IS ACTIVATED TO XIIA WHICH ACTIVATE XI TO XIA WHICH FURTHER ACTIVATE IX TO IXA ALONG WITH (VIIIA) WHICH THEN ACTIVATES X TO XA WHICH IS THE COMMON PATHWAY.
Term
WHAT 2 PATHWAYS LEAD TO THE COMMON PATHWAY?
Definition
INTRINSIC AND EXTRINSIC
Term
FACTOR WHAT AND FACTOR WHAT COMBINE WITH WHAT TO FORM WHAT?
Definition
FACTOR XA AND FACTOR VA COMBINE WITH CALCIUM (FACOTR IV) TO FORM PROTHROMBINASE
Term
WHAT DOES PROTHROMBINASE DO?
Definition
HELP INCREASE POSITIVE FEEDBACK
Term
PROTHROMBINASE CONVERTS ___ TO ___?
Definition
PROTHROMBIN (FACTOR II) TO THROMBIN (FACTOR IIA) WHICH CAUSED A THROMBIN BURST
Term
WHAT DOES THROMBIN ACTIVATE? WHAT DOES THAT DO?
Definition
FACTOR I (FIBRINOGEN) TO FACTOR IA (FIBRIN) AND STABILIZES INITIAL PLT PLUG, AS WELL AS SEVERAL UPSTREAM FACTORS.
Term
WHAT DOES THROMBIN ALSO ACTIVATE? WHAT DOES THAT DO?
Definition
XIII, WHICH CONVERTS THE FIBRIN STRANDS TO INSOLUBLE CROSS-LINKED FIBRIN POLYMERS, MAKING THE CLOT STABLE AND RESISTANT TO FIBRINOLYSIS. THE MAIN THING IS THAT THROMBIN ACTIVATE FACT I AND FACTOR XIII TO MAKE CLOT MORE STABLE.
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