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CNS PSYCH PHARM
CLUES YO
63
Medical
Post-Graduate
12/19/2011

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Cards

Term
MOA OF BENZODIAZAPINES
Definition
YOUR Z-PAMS, INCREASE GABA, CL CHANNEL FREQUENCY
Term
INDICATIONS FOR BENZODIAZEPINE USE?
Definition
ANXIETY, INSOMNIA, SEIZURE, MUSCLE CRAMPS
Term
WHAT IS THE CAUSE OF DEATH FOR BENZO AND BARB OVERDOSE?
Definition
RESPIRATORY FAILURE - THINK LIKE A NEUROMUSCULAR DZ OUTCOME
Term
WHICH ANXIOLYTIC IS USED FOR PEOPLE WHO CANNOT BE SEDATED?
Definition
BUPRIOPION (LIKE DRUG USERS OR PSYCH PT)
Term
NAME 10 BENZODIAZEPINES?
Definition
FLOUREPAM, ZOLPIDEN, OXAZEPAM, TRIAZELAM, TOMAZEPAM, DIAZEPAM, LORAZEPAM, CLONEZAPAM, CHLORIDAZEPOXIDE, MIDAZELAM
Term
SHORTEST ACTING BENZO?
Definition
FLOREZAPAM - ALAZOPRAM (IF LISTED)
Term
LONGEST ACTING BENZO?
Definition
ZOLPIDEM (AMBIEN SLEEPING PILL, MAKES SENSE!)
Term
MEDIUM DURATION BENZO?
Definition
OXAZEPAM AND TRIAZELAM
Term
BENZO USED IN ELDERLY TO INITIATE SLEEP?
Definition
TRIAZELAM - (TRI - TRYING TO GO TO SLEEP)
Term
BENZO USED FOR OLD PEOPLE WITH DIFFICULTY MAINTAINING SLEEP?
Definition
TOMAZEPAM (MAZE - MAINTAINING SLEEP)
Term
FOUR BENZO'S MOST COMMONLY USED IN SEIZURES
Definition
DIAZEPAM, LOREZEPAM, CLONAZEPAM, CHLORDIAZEPOXIDE
Term
TWO BENZO'S MOST COMMON USED FOR STATUS EPILEPTICUS?
Definition
CLODIAZEPAM AND LORAZEPAM (FIRST LINE LOREAZEPAM -- THEN FOLLOW WITH PHENYTOIN TO DECREASE REOCCURENCE****)
Term
BENZO MOST COMMONLY USED FOR RESTLESS LEG SYNDROME?
Definition
CLONAZEPAM
Term
BENZO MOST COMMONLY USED FOR ABSENT SEIZURES IN CHILDREN?
Definition
CLONAZEPAM - READ CAREFULLY, FIRST LINE TREATMENT FOR ABSENT SEIZURES IS ETHOSUXIMIDE (A Ca2+ CHANNEL ANTI-EPILEPTIC) - FIRST LINE BENZO FOR KIDS HOWEVER - CLONEZAPAM
Term
BENZO THAT IS BEST FOR ANXIETY IN MIDDLE AGED FEMALES?
Definition
LORAZEPAM
Term
BENZO MC USED FOR ALCOHOLIC WITHDRAWL?
Definition
CHLORDIAZEPOXIDE
Term
BENZO USED FOR SHORT PROCEDURES (LIKE GI ENDOSCOPY)?
Definition
MIDAZELAM
Term
BENZO WITH 45 MIN ANTEROGRADE AMNESIA?
Definition
MIDAZELAM - PT WITH ENEMA NEVER REMEMBERS WHAT HAPPENED TO EM
Term
ANTEDOTE FOR BENZO OVERDOSE?
Definition
FLUMAZENIL - CUZ BENZO FLU OUTTA CONTROL
Term
MOA OF BARBITURATES?
Definition
INCREASES GABA, CL CHANNEL DURATION - B/C TURATES SOUNDS LIKE DURATE-DURATION
Term
INDICATION OF BARBITURATES?
Definition
INSOMNIA, SEIZURES, MUSCLE CRAMPS
Term
WHY ARE BARBITURATES NOT INDICATED WITH ANXIETY??***
Definition
BECAUSE THEY ARE TOO SEDATING - THEY'LL JUST PASS OUT ALL DAY
Term
LONGEST ACTING BARBITURATE?
Definition
PHENOBARBITAL - BARBIE, KIDS, USED FOR SEIZURES IN KIDS, LONGEST ACTING TO MAKE SURE THEY ARE BALANCED LONGER
Term
SHORTEST ACTING BARBITURATE?
Definition
THIOPENTAL
Term
BARBITURATE MOST COMMONLY ABUSED ON THE STREET?
Definition
SECOBAARBITAL
Term
TREAT FOR BARB OVERDOSE?
Definition
HCO3 AND DOXAPRAM
Term
BARB MOST COMMONLY USED FOR GENERALIZED SEIZURES ON CHILDREN?
Definition
PHENOBARBITAL
Term
3 DRUGS USED TO TREAT BIPOLAR?
Definition
1/LITHIUM
2/VALPROIC ACID
3/CARBAMAZEPINE
Term
MOA OF LITHIUM?
Definition
MOOD STABILIZER - WORKS BY LOOKING LIKE SODIUM AND STABILIZES CELLS
Term
SIDE EFFECTS OF LITHIUM?
Definition
HYPOSALT, HYPERTHYROID, HYPOTHYROID, HYPER-Ca2+, HYPO-PHOSPHATE, NEPHROGENIC DI, EPSTEINS ANOMLY (FETUS GETS IT IF MOMMY TOO Li DURING PREGNANCY, ITS TRICUSPID REGURG DUE TO ATRIALLIZATION)
Term
HOW DOES LI CAUSE NEPHROGENIC DI?
Definition
IT INHIBITS ADH RECEPTORS IN KIDNEY
Term
HOW DOES Li CAUSE HYPONATREMIA?
Definition
B/C IT LOOKS LIKE SODIUM, THE KIDNEY HOLDS ON TO IT INSTEAD OF THE REAL THING
Term
HOW DOES Li CAUSE hypoTHYROIDISM?
Definition
CAUSES DECREASED PRD OF T4 AND INTERFERE WITH de-iodination of T4 to T3 - IT WON'T LET IT GET ACTIVATED BACK TO T3 (aCTIVE FORM)
Term
HOW DOES LITHIUM CAUSE HYPERCALCEMIA?
Definition
IT BINDS TO PTH RECEPTORS, LINK WITH HYPERTHYROIDISM AND TRYING TO RELEASE LOTS OF CALCITONIN
Term
MOA OF CARBAMAZAPINE?
Definition
SODIUM CHANNEL BLOCKER
Term
SIDE EFFECTS OF CARBAMAZEPINE
Definition
AGRANULOCYTOSIS AND SIADH
- OTHER RX WITH SE OF AGRANULOCYTOSIS
- PTU/MMI, METHOTREXATE, COLCHICINE, CLOZAPINE, CARBAMAZEPINE, PROCAINAMIDE/TOCAINAMIDE, PENICILLAMINE
Term
INDICATION FOR CARBAMAZEPINE?
Definition
TEMPORAL LOBE SEIZURES WITH HALLUCINATIONS, 3RD LINE FOR BIPOLAR DISORDER, SHOOTING NEUROPATHY (CHRONIC TX WITH TCA AMITRIPTYLINE)
Term
HOW DOES CARBAMAZAPINE CAUSE SIADH?
Definition
WELL SINCE ITS 3RD LINE BIPOLAR HINT AT LI MOA? - ANT ITS OWN MOA OPPOSITE REACTION HERE- STIMULATES THE ADH RECEPTORS OF KIDNEY
Term
MOA OF VALPROIC ACID
Definition
MOOD STABILIZER - Blocks sustained high-frequency repetitive neuronal firing (similar to phenytoin & carbamazepine) - WAH? -- BLOCKS CA, NA, NMDA PATHWAY, PROMOTES GABA AND K+
Term
INDICATION OF VALPROIC ACID?
Definition
2ND LINE BIPOLAR
1ST LINE MYOTONIC SEIZURES (HAND STUCK ON DOOR KNOB, SUSTAINED CONTRACTION)
1ST LINE MIXED SEIZURES (PARTIAL OR GEN TONIC CLONIC)
Term
SIDE EFFECTS OF VALPROIC ACID?
Definition
BONE MARROW SUPPRESSION
Term
WHAT IS MAIN CAUSE OF DEPRESSION?
Definition
SEROTONIN AND NOREPINEPHRINE
Term
MOA OF TRI-CYCLIC ANTI-DEPRESSANTS (TCA)?
Definition
BLOCKS REUPTAKE OF ALL CATECHOLAMINES, STRONG ANTI-CHOL EFFECTS, BLOCKS ALPHA 1 RECEPTORS BY ACCIDENT (VASODIATORY EFFECTS), and AV CONDUCTION BLOCK IN HEART - ALSO MCC OF DEATH FROM OVERDOSE FOR THAT REASON
Term
CLUE FOR ANTI-CHOL EFFECTS?
Definition
SYMPATHETIC WITH HOT DRY SKIN
Term
NAME 5 TCA'S
Definition
CANDI - CLOMIPRAMINE, AMITRYPTALINE, NORTRYPTALINE, DESPIRAMINE, IMIPRAMINE
Term
TCA USED FOR BEDWETTING IN CHILDREN?
Definition
IMIPRAMINE
Term
TCA USED FOR CHRONIC PAIN OR NEUROPATHY?
Definition
AMITRYPTALINE
Term
TCA USED FOR OCD?
Definition
CLOMIPRAMINE
Term
SHORTEST ACTING TCA'S?
Definition
NORTRYPTALINE N' DESIPRAMINE
Term
MOA OF SSRI?
Definition
INHIBITS REUPTAKE OF SEROTONIN
Term
NAME 4 SSRI'S?
Definition
FLiPS! - FLUXETINE, LUVOXATINE, PAROXATINE, n SERTRALINE
Term
SIDE EFFECT FOR SSRI?
Definition
ANORGASMIA, REMEMBER SEROTONIN IS SYMP IN THE BRAIN BUT IN THE PNS (PENIS - WHOLE BODY) ITS PARASYMPATHETIC, SO PENIS IS FULL PARAYSMPATHETIC AND CAN'T SYMPATHETIC TO SHOOT (POINT N' SHOOT THEORY)
Term
NAME 4 MOAI'S?
Definition
PITS - PHENYLZINE, ISOCARBOXAZID, TRANYLCYPRAMINE, SELEGELINE
Term
FOODS AVOIDED WHEN ON MOAI'S?
Definition
WINE N' CHEESE - CAAUSES HYPERTENSION CRISIS B/C WINE N' CHEESE PREVENT BREAKDOWN OF CATECHOLAMINES SO TOO MUCH TRYPTOPHAN N' TYRAMINE FROM FOOD FEEDING INTO EPI/NOREPI PROD CYCLE
Term
WINE N' CHEESE CONTRACINDICATED WITH MOAI'S BECAUSE?
Definition
HYPERTENSIVE CRISIS TERMED SEROTONIN SYNDROME
Term
HOW LONG TO WAIT AFTER STOPPING MOAI FOR SWITCHING DRUGS TO SSRI'S? WHAT IS THE WASHOUT PERIOD OF MOAI?
Definition
ONE MONTH
Term
NAME AN MOABI?
Definition
SELEGELINE
Term
MOA OF BUPRIOPION?
Definition
BLOCKS REUPTAKE OF SEROTONIN
Term
INDICATION OF BUSPRIOPION?
Definition
USED IF SEXUAL DYSFUNCTION COMES ON FROM SSRI USE OR OTHER ANTI-DEPRESSANTS - ALSO USED FOR SMOKING CESSATION
Term
SIDE EFFECTS OF BUPRIOPION?
Definition
DECREASED SEIZURE THRESHOLD
Term
INDICATIONS FOR ELECTROCONVULSIVE THERAPY?
Definition
PERSON WHO IS ACTIVELY SUICIDAL OR WITH INTRACTABLE DEPRESSION - BELIEVE IT OR NOT SAFE FOR PREGNANT CRAZY BITCHES. - ONLY SIDE EFFECT NOTED, AMNESIA (PT WON'T REMEMBER WHO BROUGHT THEM IN, AND WORSE)
Term
#1 SIDE EFFECT OF ECT?
Definition
AMNESIA
Term
HOW DO AMPHETAMINES WORK?
Definition
THEY CAUSE THE RELEASE OF PREFORMED CATECHOLAMINES - JUST DUMPING IT INTO SYNAPES
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