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CNS pharm-local anesthetics
CNS pharm-local anesthetics
16
Medical
Professional
04/05/2009

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Cards

Term
Inhaled (volatile) anesthetics
Definition

NO

Halothane

Isoflurane

Desflurane

Sevoflurane

 

NO-DISH

Term
IV induction agents
Definition

Thiopental

Propofol

Etomidate 

Ketamine

 

KEPT

Term
NO
Definition
Class: inhalational anesthestic
 
Activity: unconsciousness, analgesia, muscle relaxation, reflex ablation
 
MAC 11%, colorless, odorless, tasteless
 
AE:minimal CV, little muscle relaxation, no malignant hyperthermia, difuse into open space, NV
 
Use: GA, give at conc 50-75%
 
Related drugs: halothane, Isopflurane, desflurane, sevoflurane
 
 
Term
halothane
Definition
class: inhalational anesthetic, MAC 0.75, smell ok
 
activity: unconsciousness, analgesia, muscle relaxation, reflex ablation
 
AE: rare hepatic failure
 
Use: GA, vaporizer
 
Related: NO, sevoflurane, isoflurane, desflurane, sevoflurane
Term
Isoflurane
Definition
class: inhalational anesthetic, MAC 1.15%, smells bad
 
activity: unconsiousness, analgesia, muscle relaxation, reflex ablation
 
AE:limited CO effect
 
Use: GA, vaporizer
 
Related drugs: NO, halothane, isoflurane, desflurane, sevoflurane
Term
Thiopental
Definition
class: Barbituate
 
activity: IV induction anesthetic
 
AE: CV effects (reduced SVR, CO), reduced ventilatory drive
 
Use: induce GA (IV)
 
Related drugs:Propofol, Etomidate, Ketamine
Term
Propofol
Definition
class: Barbituate-like
 
activity: IV induction anesthetic, rapid recover, fewer postop effects
 
AE: hangover, NV, pain on injection, antiemetic, euphoric
 
Use: induce GA (IV)
 
Related drugs:Thiopental, Etomidate, Ketamine
Term
ketamine
Definition
class: NMDA antagonist
 
activity: Dissociative anesthesia, longer duration
 
AE: Increased HR, CO, BP, increased ICP, emergence delirium, hallucinations
 
Use: induce GA (IM)
 
Related drugs:Propofol, Etomidate, Thiopental
Term
Midazolam
Definition
class:Benzodiazepine
 
activity: hypnotic-causes unsciousness
 
AE: ventilatory depression
 
Use: premedicant to GA that's sedating and decreases anxiety and amnesia
Term
droperidol
Definition
class: Butyrophenone
 
activity: 5-HT2 blockade, alpha adrenergic agonist
 
AE: simliar to haloperidol, less orthostatic hypotension, sedatoin, extrapyramidal effects
 
Use: antiemetic, IM, IV

Term
Ondansetron
Definition

5-HT3 antagonist

 

 few AEs

 

anti emetic

Term
Aprepitant
Definition

NK1 antagonist

 

Few AEs

 

anti-emetic

Term
scopolamine
Definition

mACh antagonist

 

dry mouth, blurred vision

 

anti emetic

 

patch

Term
fentanyl
Definition

Opioid

 

greater lipid solubility with more rapid onset, no histamine release

 

over time accumulated and acts like drug with long duration

Term
remifentanil
Definition
newest opioid potency=fentanyl
ester, fast recovery
 
No dose adj for age, weight, MF, hepatic/renal function
 
rapid emergence
Term
naloxone
Definition
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