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CNS DRUGS
N/A
47
Veterinary Medicine
Undergraduate 2
10/29/2013

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
Phenothiazine Tranquilizers
Definition

Alpha 1 adrenergic antagonist 

 

Slows GI tract and treats vomiting - suppresses the CRTZ

 

Acepromazine/Chlorpromazine

 

Prochlorperazine/Promazine

 

Causes drowsiness and increase of salivation

Term
Benzodiazepines
Definition

CNS suppressant 

 

Seditives and muscle relaxer

 

Diazepam/alprazolam 

 

Midazolam/zolazepam 

 

Oral and injectable 

 

Term
Alpha 2 Agonists
Definition

Depress CNS

 

Xylazine/Medetomidine

 

Detomidine/Dexmeditomidine

 

Romifidine

Term
Xylazine (Rompun)
Definition

Alpha 2 agonist 

 

Sedation, limited analgesia and inducing vomiting

 

injectable 

 

Lowers HR and BP, vomiting 

 

Term
Detomidine (Dormosedan)
Definition

Alpha 2 adrenergic agonist 

 

Standing anesthesia in horses 

 

injectable

 

causes sweating and decreased HR and BP

Term
Medetomidine (Domitor)
Definition

Alpha 2 Adrenergic agonist 

 

Induction/pre anesthetic

 

injectable

 

lowers HR and RR, hypothermia 

 

Antisedan reverses it

Term
Dexmeditomidine (Dexdomitor)
Definition

Alpha 2 adrenergic agonist 

 

Pre anesthetic 

 

Reversal agent - antisedan

Term
Romifidine (Sedivet)
Definition

Alpha 2 agonist

 

horse sedation 

 

long sedation 

Term
Phenobatbital
Definition

Long acting barbiturates

 

Class IV CS

 

Anti seizure drug

 

iV and oral

 

causes PU/PD and inflammation of the liver 

Term
Pentobarbital
Definition

Shrot acting barbiturate 

 

Class II CS

 

Emergencies/euthanasia  

 

injectable 

 

CNS depression, PU/PD, tissue necrosis 

Term
Ketamine (Ketaset)
Definition

Dissociative agent

 

Class III CS

 

maintenance of reflexes and increase muscle tone

 

Good somatic analgesia

 

Injectable

 

ELU in dogs

Term
Tiletamine
Definition

Dissociative agent

 

Class III CS

 

used with zolaspane 

 

injectable

Term
Morphine
Definition

Natural Opioid agonist agent

 

Class II CS

 

Analgesic - mu

 

oral and injectable 

 

 

 

Term
Hydromorphone
Definition

Opioid agonist 

 

sedation and analgesic 

 

injectable 

 

causes panting and resp depression

Term
Butorphanol (Torbugesic, Torbutrol)
Definition

Synthetic opioid agonist

 

Pre anesthetic - BAA and antitussive

 

Class IV CS

 

oral and injectable 

 

 

Term
Fentanyl (Duragesic)
Definition

Synthetic opioid agonist 

 

Class II  CS

 

analgesic 

 

injectable and topical (patch)

Term
Hydrocodone
Definition

Synthetic opioid agonist

 

Class III CS

 

antitussive in dogs

Term
Lomotil
Definition

Synthetic opioid agonist 

 

made up from diphenoxylate and atropine

 

Class V CS

 

anti diarrheal

 

oral

Term
Apomorphine
Definition

Synthetic opioid agonist 

 

affects CRTZ

 

used for vomiting 

 

injectable and oral

Term
Codeine
Definition

Synthetic opioid agonist 

 

Class III CS

 

antitussive in dogs 

 

oral

Term
Buprenorphine (buprenex)
Definition

Synthetic opioid agonist 

 

analgesic 

 

injectable

 

Class III cs

Term
Tramadol
Definition

Opioid agonist 

 

analgesic and inhibits reuptake of serotonin and norepinephrine 

 

contra: ssris 

Term
Opioid Antagonists
Definition

Displace narcotics at receptor site

 

Naloxone (narcan) - pure 

 

Nalorphine - partial

Term
Neuroleptanalgesia
Definition
Combination of opioid and tranquilization or sedatives
Term
Anticonvulsants - Control
Definition

Diazepam

 

Phenobarbital

 

Pentobarbitol

Term
Postassium Bromide (K Bro Vet)
Definition

Anitconvulsant prevention

 

Used as an adjunct to other anticonvulsants 

 

Tablets and solution

 

Can cause an upset stomach

 

 

Term
Zonisamides (Zonegran)
Definition

Anticonvulsant prevention

 

Sedation

 

Oral and capsules

 

Can cause anorexia and nausia 

Term
Gabapentin (Neurontin)
Definition

Anticonvulsants - prevention

 

Supresses nerves

 

Tx of neuralgia

 

Oral 

Term
MAC
Definition

Minimum alveolar concentrations

 

Amount of anesthetic in alveoli that stops groos purposful movement in 50% of patients

 

Low mac - high potentcy

Term
Partition Coefficient
Definition

Ratio of anesthetic in blood to amount in alveoli

 

High partition coefficientcy = faster mitabolization

Term
Doxapram (Dopram-V)
Definition

CNS stimulate

 

stimulates the respiratory center in madulla oblingota 

 

Injectable

Term
Inhalant Anesthetics
Definition

MAC, PC, vapor pressure 

 

Little biotransformation

 

Quicker alteration of depth of anesthesia vs. injectable

 

Worry about equipment and exposure to personal

Term
Factors that Effect Dilivery of Inhalant Anesthetics
Definition

Vaporizer setting

 

Oxygen flow

 

Dead space

 

Ventilation

 

Tissue perfusion

 

Solubility of agent

Term
Factors that Affect Removal of Inhalant Anesthetics
Definition

Amount of alveolar surface available for exchange

 

Molecular weight

 

Cardiac output 

Term
Isoflurane
Definition

Ihalant anesthetic 

 

Rapid induction and recovery

 

Maintains CO and heart rythm

 

low metabolism

 

Can cause respiratory depression

Term
Sevoflurane
Definition

Inhalant anesthetic

 

Very rapid induction and recovery

 

Safe CV and respiratory

 

Low metablism

 

$$

Term
Propofol (Propoflo)
Definition

Hypnotic agent

 

Rapid sedation and induction

 

Short term 

Term
Guaifenesin (GG)
Definition

Anesthetic agent

 

Skeletal muscle relaxer

 

Used for inductio

 

Prolongation of injection field anesthesia 

 

 

Term
Anxiolytics
Definition

Behavior Drugs

 

Benzodiazepines

 

Azapirones

 

Term
Antidepressants
Definition

Used for anxity and behavior problems

 

Tricyclic antidepressants

 

Selective serotonin reuptake inhibitors

 

Monoamine oxidase-B inhibitors

 

Synthetic progestine

Term
Clomipramine (Clomicalm)
Definition

Tricyclic antidepressant

 

Prevents reuptake of norepinephrine and serotonin

 

Used for OCD, fear, agression, seperation anxity

 

Can increase HR and cause dry mouth

Term
Fluoxetine (Prozac)
Definition

SSRI

 

Used for OCD, agression, fear

 

Less side effects than TCAs

 

$$

Term
Wash Out Period
Definition
Weaning off a drug
Term
Selegeline (Anipryl)
Definition

MAO-B inhibitor

 

Prevents dopamine breakdown

 

Increases thinking

Term
Mirtazapine
Definition

Tetracyclic antidepressant

 

Increases serotonin and norepinephrine

 

Appitie stimulant

 

 

Term
Megeststrol Acetate (Megace)
Definition

Synthetic Progestin

 

Changes hormone level 

 

Used for spraying, agression

 

A lot of side effects

Term
Euthanasia Agents
Definition

Fast onset for humane death

 

Pentobarbitol 

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