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CNS drugs
flashcards for final exam
61
Nursing
Undergraduate 3
12/15/2009

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Term
narcotics
Definition
very strong pain relievers
Term
Opioids often given with these types of drugs for pain relief
Definition
NSAIDs, Antidepressants, Anticonvulsants, Corticosteroids
Term
Narcan and Revia
Definition
opiate reversal drugs
Term
Acetaminophen
Definition
nonopioid analgesic and antipyretic
Term
acetylcysteine
Definition
tylenol antidote
Term
Maximum daily dose of acetominophen for average adult is?
Definition
4,000 mg/day
Term
ketorolac (Toradol)
Definition
NSAID
Term
indomethacin (Indocin)
Definition
NSAID for bone, joint, and muscle pain
Term
diclofenac (Cataflam)
Definition
NSAID for osteoarthritis
Term
diflunisal (Dolobid)
Definition
NSAID for rheumatoid arthritis
Term
salicylates (Asprin)
Definition
NSAID, most widely used drug in the world
Term
allopurinol (Zyloprim)
Definition
NSAID: antigout drug that reduces production of uric acid
Term
colchicine
Definition
NSAID: antigout that reduces inflammatory response to deposits of urate crystals in joint tissue
Term
Benemid and Anturane
Definition
NSAID: antigout that increases excretion of uric acid in the urine
Term
Cytotec
Definition
can be used to reduce GI effects of NSAIDs
Term
NSAIDS and Coumadin
Definition
Coumadin has increased effect (thinner blood)
Term
salicylate toxicity
Definition
tinnitus and hearing loss in adults. CNS effects in children. Occurs at serum levels past 40-60 mg/dL
Term
Auranofin
Definition
NSAID for rheumatoid arthritis: 25% gold, oral dose
Term
Aurothioglucose
Definition
NSAID for rheumatoid arthritis. 50% gold, parental dose
Term
Gold sodium thiomalate
Definition
NSAID for rheumatoid arthritis: 50% gold, weekly deep IM injection
Term
-barbital drugs
Definition
Barbiturates. CNS depressants
Term
reduced REM sleep caused by
Definition
Barbiturate adverse effect
Term
MAOIs and barbiturates
Definition
MAOIs inhibit metabolism and prolong the effects of barbiturates
Term
-lam and -pam meds
Definition
Benzos. CNS depressants
Term
Sonata, Ambien, Lunesta
Definition
Nonbenzo hypnotics. Used for insomnia not for anxiety
Term
Rebound insomnia
Definition
May occur for a few nights after a 3-4 week regimen of CNS depressants has been discontinued.
Term
dantrolene (Dantrium)
Definition
muscle relaxant- also used for malignant hyperthermia crisis
Term
Simple seizures
Definition
person is alter and remebers it
Term
complex seizures
Definition
Person is out of it and doesn't remember it
Term
gerneralized seizures
Definition
Person always loses consciousness
Term
status epilepticus
Definition
30+ minutes of continuous seizures. Is life threatening
Term
Drug of choice for status epilepticus
Definition
Valium
Term
valproic acid (Depakote)
Definition
widely used first line antiepileptic drug
Term
Reboud seizures
Definition
can occur if antiepileptic therapy is discontnued abruptly
Term
Mixing Dilantin
Definition
ONLY with normal saline. May precipitate with anything else
Term
Parkinson's disease - generally
Definition
Body needs more dopamine and wants less ACh
Term
MAOIs and tyramine
Definition
"Cheese effect" that causes severe hypertension
Term
Levodopa "on-off phenomenon"
Definition
Swings from good to bad responses
Term
Selegiline
Definition
MAOI for Parkinson's. Used in combination with levodopa or levodopa-carbidopa.
Term
amantadine (Symmetrel)
Definition
Dompaminergic therapy for Parkinson's. Causes release of dopamine.
Term
Tasmar and Comtan
Definition
COMT inhibitors: inhibit enzyme resp. for the breakdown of levodopa.
Term
Tolcapone
Definition
Last resort antiparkinson drug
Term
Anticholinergic drugs for Parkinson's
Definition
Block the effects of ACh
Term
If taking Levodopa, avoid:
Definition
Foods high in vitamin B6 (pyridoxine)
Term
Hypertensive crisis:
Definition
Can be caused by taking Levodopa with MAOI antidepressants
Term
BuSpar
Definition
non-sedating and non-habit forming antianxiety med.
Term
-azepam or -azelam (lam and pam)
Definition
Benzo antianxiety drugs
Term
Versed
Definition
IV only, causes conscious sedation
Term
Flumazenil
Definition
benzo antidote
Term
Lithium therapeutic range
Definition
between 0.6 and 1.2 mEq/L
Term
St. John's Wort
Definition
Do not take with SSRIs
Term
Advantage of SSRIs over tricyclics and MAOIs:
Definition
little to no effect on the cardiovascular system
Term
amitriptyline (Elavil)
Definition
Common tricyclic
Term
Tricyclic overdose
Definition
Very lethal! 70-80% die before getting to the hospital due to seizures or dystrhythmias.
Term
Nardil and Parnate
Definition
MAOI antidepressants
Term
Haldol
Definition
Antipsychotic with lots of side effects like neurologic malignant syndrome (NMS)
Term
Neuroleptic malignant syndrome
Definition
Potentially life-threatening, consists of: high fever, unstable BP, muscle breakdown, thin blood
Term
Extrapyramidal symptoms (EPS)
Definition
Involuntary muscle symptoms, akathisia, acute dystonia.
Term
EPS treated with?
Definition
Cogentin and Artane (parkinson's meds)
Term
Tardive dyskinesia
Definition
Irreversable abnormal movements of the facial muscles.
Term
choreoathetosis
Definition
wavelike wormlike movements of the extremities
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