Term
| What are CNS Depressants: Sedative-hypnotics drug types? |
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Definition
- Nonbarbiturate , nonbenzodiazepine
- Barbiturates
- Benzodiazepines
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Term
| What are specific prototypes of CNS depressants (sedative-hypnotics)? |
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Definition
- phenobarbital (Luminal, et al)
- diazepam (Valium)
- Buspirone (Buspar)
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Term
| How does the barbiturate phenobarbital work? |
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Definition
- Suppresses REM sleep.
- Can cause blood dyscrasias and liver damage. Various preparations differ in onset and duration of action
- Induce liver enzymes, so tolerance develops; affect some other drugs as well.
- S & S of allergy (can be severe): prickly sensation, then edema of m. membranes of lips, mouth, tongue, face, viscera.
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Term
| What are the unique features of the benzodiazepine diazepam (valium) ? |
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Definition
- Suppresses non-REM sleep.
- Overdose antidote: flumazenil (Mazicon)
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Term
| What are the unique features of the nonbarbiturate, nonbenzodiazepine Busprone (Buspar) ? |
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Definition
- Relieves anxiety with less CNS depression
- sedation
- risk of dependence
- Benefits not apparent for 3-4 weeks
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Term
| What is the N/C Assessment of CNS Depressants for Sedative-Hypnotics? |
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Definition
- Deficient knowledge of sedative-hypnotic therapy: Patient teaching should include:
- short term use
- resole basic problem
- complementary therapy
- risk for dependence
- CNS drug interactions
- Sedation ;safety
- gradual withdrawal
- effective for sleep 2-4 weeks
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