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CNS Depressants
All Classes
64
Pharmacology
Professional
06/19/2010

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Cards

Term
Name some Narcotic Analgesics
Definition
morphine sulfate/ Duramorph, Astromorph
meriperidine/ Demerol
nalbuphine/ Nubain
butorphanol/ Stadol
hydromorphone/ Dilaudid
fentanyl/ Sublimaze
naloxone/ Narcan
Term
What 2 Narcotic analgesics are synthetic
Definition
nalbuphine/ Nubain
butorphanol/ Stadol
Term
What are some Non narcotic analgesics
Definition
aspirin/ acetylsalicylic acid, ASA, Bayer
acetaminophen/ Tylenol
ketorolac/ Toradol
Term
What are the General anesthetics we use
Definition
nitrous oxide/ Nitronox
methohexital/ Brevitol
thiopental/ Pentothal
Term
What general anesthetics do we give IV and are also Barbiturates
Definition
thiopental/ Pentothal
methohexital/ Brevitol
Term
Name the Barbituates
Definition
methohexital/ Brevital
thiopental/ Pentothal
phenobarbital/ Luminal

AKA anticonvulsants
Term
What are some Benzodiazepines
Definition
diazepam/ Valium
midazolam/ Versed
lorazepam/ Ativan

These are also anticonvulsants
Term
What are some other anticonvulsants other than the Benzo's or Barbiturates
Definition
phenytoin/ Dilantin aka Beta blocker
magnesium sulfate
Term
Name the Sedative hypnotics
Definition
etomidate/ Amidate
propofol/ Diprivan
ketamine/ Ketalar

also are classed as anesthetics
Term
Which sedative hypnotic produces some analgesia and amnesia
Definition
etomidate/ Amidate
Term
Phenothiazines and other drugs that cause dystonic reactions are what
Definition
chlorpromazine/ Thorazine
prochlorperazine/ Compazine
droperidol/ Inapsine
haloperidol/ Haldol
Term
Of the phenothiazines which can be classified as their own group of drugs called Butyrophenones
Definition
droperidol/ Inapsine
haloperidol/ Haldol
Term
Analgesia means what
Definition
decrease in perception of pain
Term
Anesthesia means
Definition
decrease sensation of pain
Term
What two classes are analgesics divided into
Definition
Opiod/ Narcotic and
Non Opiods
Term
Opiods act on what receptor sites
Definition
Endorphin
Term
What do opiods/ narcotics do when they act on the endorphin receptors
Definition
decrease their ability to propagate pain impulses

sop the initiation of new pain impulses
Term
What are some endorphin receptors
Definition
Mu--most important
Kappa
Sigma-undesirable effects
Term
General actions of Opiods
Definition
Analgesia
Respiratory depression
Decreased PVR-v preload, v afterload
Constipation
^ ICP
Sedation
Euphoria
Term
Adjunct drugs that help potentiate the effects of analgesics are
Definition
Benzo's-Versed
Antihistamines- Benadryl
Caffine
Term
Narcan/ naloxome is the antidote for what class of drugs
Definition
Opiods-Narcotic analgesics
Opiod Antagonist- blocks
Prototype drug
Term
Because Narcan has a shorter half life than the narcotic what might you have to do and look out for
Definition
HAVE TO REDOSE
Make sure your patient stays stable
Term
If something is said to be a CNS depressant what effects would you expect
Definition
Decrease in the following:
HR
RR
BP
LOC
Term
56 y/o M CO chest pain with a BP of 160/100, RR 22, and a 10 on a pain scale and he tells you he is dying, also has history of CHF. What drug would you give
Definition
morphine
Term
What contraindication covers all the Narcotic Opiod Analgesics
Definition
Head injury-cause ^ICP
Term
NSAIDS inhibit the synthesis of what
Definition
cyclooxygenase/ Cox which is an enzyme
Term
cyclooxygenase/ Cox which is an enzyme responsible for the synthesis of what
Definition
Prostiglandins and Thromoxane
Term
Prostiglandins are responsible for
Definition
Pain response
^ in blood flow
Inflammation
V gastric acid secretion
Fever
Term
How does ASA increase blood flow
Definition
it is a anti-platelet aggregator
Term
What other NSAIDS can be given IM or IV and is great for vomiting pt's
Definition
ketorolac/ Toradol
Term
What other narcotic analgesic besides morphine is used for RSI
Definition
fentanyl/ Sublimaze
Term
Classes of Sedative Hypnotic Drugs are
Definition
Anticonvulsants, Barbiturates and Bezodiazepines
Term
Benzo's and Barbituates both promote what CNS receptor
Definition
GABA
Term
GABA is the chief neurotransmitter of the CNS what does it do
Definition
GABA is responsible for making you sleepy slowing you down.
Inhibits wake fullness and alertness
Term
Both Benzo's and Barbiturates promote GABA which one Stimulates it
Definition
Barbiturates
Term
Benzo receptors found in cerebellum mediate what
Definition
Anxiety and Sedation
Term
What do the benzo receptors in the basal ganglia and hippocampus do
Definition
Muscle relaxtion
V in memory and sensation
Term
Where are the highest concentration of Benzo receptors found
Definition
Amygdala
Term
What class Sedative Hypnotics ends with -al
Definition
Barbiturates
Term
What class of Sedative Hypnotics ends with -am
the generics
Definition
Benzodiazepines
Term
Anticonvulsants are mainly used for what
Definition
Seizures
Term
Seizures are caused by what
Definition
Hyperactive brain areas
Term
Drugs are used to treat seizures how
Definition
^ motor cortex threshold-Dilantin
Delay depolarization and prolong repolarization
Hyperpolarize membrane so can't depolarize again
Term
Anti-seizure meds AKA
Definition
Barbiturates
Anticonvulsants
Benzodiazepines
Term
What Barbiturate is also considered a anticonvulsant
Definition
phenobarbital/ Luminal
Term
If you are going to use RSI to intubate what class of drugs can you use the whole class
Definition
Barbiturates
Term
Side effect of using Mag sulfate as a anticonvulsant
Definition
Respiratory depression
Term
Conscious sedation is also called
Definition
Neuroleptanesthesia
Term
What drug is used as a local anesthetic
Definition
lidocaine/ Xylocaine
Term
Barbiturates MOA is unknown but is believed to act on what
Definition
RAS
Term
Ultra short acting Barbiturates are premedication for
Definition
RSI
Term
How long do Ultra short acting Barbiturates last
Definition
Onset 20-60 seconds
Last about 5 minutes
Term
What are more potent and more addictive benzodiazepines or barbiturates
Definition
Barbiturates
Term
Which barbiturates increases the seizure threshold
Definition
phenobarbital/ Luminal
Term
What is the major indication for Benzodiazepines besides being an anticonvulsant
Definition
Status Epilepticus
Term
What sedative hypnotics are premedication for RSI
Definition
etomidate/ Amidate
ketamine/ Ketalar
Term
Antipsychotic drugs are aimed at regulating what neurotrasmitters
Definition
Norepi
Dopamine
Seratonin
Term
What are dopamine receptors responsible for
Definition
Movement
Emotion
Cognition
Term
Disorders associated with dopamine imbalance include
Definition
Bipolar
ADD
Tourettes
Dementia
Substance abuse
Prevention emesis
Term
2 classes of drugs used as antipsychotics are
Definition
Phenothiazines
Butyrophenones
Term
Which class of drug is more potent phenothiazines or butyrophenones
Definition
butyrophenones
Term
If someone is experiencing acute dystonia what treatment can you give them
Definition
Benadyl
Term
What tx would you give to Akinesia; agitation, repetitive motions of pacing, rocking, and foot tapping
Definition
Cogentin
Term
What is the tx for tarditive dyskinesia
Definition
none
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