Term
|
Definition
Na channel Blocker
Usage dependent and used for partial and generalized tonic-clonic seizures and status epilepticus
Toxicities: Nystagmus, diplopia, ataxia stupor, cerebellar syndrome, skin rash
increases OC metab-bad cause teratogenic |
|
|
Term
|
Definition
Acts on GABA receptors to increase inhibtion
Used for partial and generalized seizures
Tox: drowsines, ataxia, vertigo |
|
|
Term
|
Definition
Increases the amount of GABA present
Tox: confusion, dizziness, sedation |
|
|
Term
|
Definition
Increases amount of GABA present by inhibiting GABA transaminase (nonspecific)
TOX: sedation and fatigue, psychosis and depression |
|
|
Term
|
Definition
Partial Seizures and maybe adjuvant for others
Typical linear dose increase
Tox: psychosis, hyperactivity and aggression maybe due to increased testosterone release |
|
|
Term
|
Definition
Na channel Blocker
Usage dependent and used for partial and generalized tonic-clonic seizures
Tox: nausea, dizziness, coma, movement disorders |
|
|
Term
|
Definition
Acts on GABA R to increase inhibition
Used for myoclonic and abscense seizures
Tox: respiratory distess, ataxia, co/behav changes
increase in seizure freq
withdrawl effects |
|
|
Term
|
Definition
acts on GABA R and is a benzo
used for status epilepticus |
|
|
Term
|
Definition
Ca Chennel Blocker (esp active Ca channels in hyprpolarized thalamic neurons)
Tx of choice in Abscense Seizures
Tox:dizzy, headache, lethargy
GI irritation, rash, BM suppression |
|
|
Term
|
Definition
Multiple mechanisms including GABA syn/metab, NaChB, CaChB)
Used for oatial, Generalized tonic-clonic, absense, and myoclonic
Dose dependent protein binding
Tox: sedation ataxia, tremor, alopecia, wt gain, cognitive slowing and developmental delays, dyskinesias, teratogenic (neural tube defects) |
|
|
