Term
Is the pain of infection constant or intermittent? Is the pain of obstruction constant or intermittent? |
|
Definition
infection - constant obstruction - intermittent |
|
|
Term
Upper ureteral obstruction may result in pain referred to where? |
|
Definition
scrotum in males or to the labium in females |
|
|
Term
Midureteral obstruction may cause pain where? |
|
Definition
ause pain in the lower quadrant - can be confused with appendicitis (on R side) and diverticulitis (on L side) |
|
|
Term
What does severe suprapubic discomfort indicate? |
|
Definition
|
|
Term
What does a Painless distended bladder indicate? |
|
Definition
|
|
Term
What does Distal urethral pain with urination indicate? |
|
Definition
|
|
Term
Where does prostatic pain radiate to? |
|
Definition
lumbosacral , inguinal canals, lower extremities |
|
|
Term
What is Pain in the flaccid penis is secondary to usually? |
|
Definition
|
|
Term
What does pain in the erect penis secondary to usually? |
|
Definition
Peyroine disease or priapism |
|
|
Term
How long may pain from treated acute epididymitis last? |
|
Definition
|
|
Term
What is the normal measurement of a testicle and what is the normal consistency? |
|
Definition
measure 4.5 x 2.5 Rubbery Consistency |
|
|
Term
Where does the epididymus lie in relationship to the testis? |
|
Definition
|
|
Term
Are masses arising from within the testes usually malignant or benign? |
|
Definition
|
|
Term
Are masses arising from the epididymis and spermatic cord structures usually malignant or benign? |
|
Definition
|
|
Term
What is tranillumination used for? |
|
Definition
distinguishing solid and cystic lesions |
|
|
Term
If a pt presents with usually painless, firm, solid lesions within the substance of the testis that do not transilluminate, what condition do you suspect? |
|
Definition
|
|
Term
14 y/o male pt presents with intense pain in scrotum that began this morning and has increasingly worsened. Scrotum is enlarged, red, and edematous. He is N/V and has a temp of 99.7F. The testicle is quite tender, is located high in scrotum with a transverse lie and the cremasteric reflex is absent. What condition do you suspect? |
|
Definition
|
|
Term
In what age do 2/3rds of testicular torsion cases occur? |
|
Definition
|
|
Term
What type of invagination is described as a torsion occurring within the tunica vaginalis? |
|
Definition
|
|
Term
What type of invagination is described as a torsion involving twisting testis, cord and processus vaginalis? |
|
Definition
|
|
Term
In which type of pts is Extravaginal torsion MC? |
|
Definition
particular in newborns, and in undescended testis |
|
|
Term
What imaging should be used for testicular torsion? |
|
Definition
Doppler US is diagnostic. Decreased flow is torsion. |
|
|
Term
What does increased flow on the doppler U/S of the testes indicative of? |
|
Definition
think inflammation (reliable in first 12 hours). |
|
|
Term
Pt presents with heaviness in his scrotum and mass. His girlfriend said he should come in, but says he feels this is normal for him. What condition do you suspect? |
|
Definition
|
|
Term
What condition is described as a collection of fluid between the two layers of tunica vaginalis? |
|
Definition
|
|
Term
|
Definition
More common in 1st year of life |
|
|
Term
When is a hydrocele painful? |
|
Definition
Painful if large or infected |
|
|
Term
How is the diagnosis of a hydrocele made? |
|
Definition
made with transillumination |
|
|
Term
Which type of hydrocele is described as a closure of processus vaginalis traping peritoneal fluid? |
|
Definition
Non-communicating hydrocele |
|
|
Term
Which type of hydrocele is described as failure of closure of processus vaginalis? |
|
Definition
|
|
Term
Which type of hydrocele is described as closure of distal processus, trapping fluid in mid portion of processus vaginalis? |
|
Definition
|
|
Term
What is the treatment for a hydrocele? |
|
Definition
|
|
Term
What condition is described as engorgement of the internal spermatic veins above the testis, resulting from incompetence of the venous valves of internal spermatic venous system? |
|
Definition
|
|
Term
What side is a varicocele MC? |
|
Definition
MC found on the Left side |
|
|
Term
Where does the L spermatic vein empty into? |
|
Definition
empties into L renal vein |
|
|
Term
Where does the R spermatic vein empty into? |
|
Definition
|
|
Term
If varicocele presents solely on right side, remains dilated while pt assumes the supine position, or if they occur abruptly or enlarge rapidly, what condition should you suspect? |
|
Definition
be suspicious of retroperitoneal or renal mass causing obstruction |
|
|
Term
What kind of lasting effects can occur from a varicocele? |
|
Definition
May cause atrophy of both testes, may lead to infertility |
|
|
Term
When is surgery indicated for a varicocele? |
|
Definition
Surgery indicated if assoc with infertility and/or pain |
|
|
Term
A 42 y/o male presents to your practice complaining of swelling in his groin. States he noticed the swelling when he went to shower after doing heavy lifting in the garden. What condition do you suspect? |
|
Definition
|
|
Term
Which type of hernia is usually found within the scrotum? |
|
Definition
|
|
Term
Which type of hernia is described as coming through the external inguinal ring, so examining fingers cannot get above it within the scrotum? |
|
Definition
|
|
Term
What is the treatment for a inguinal hernia? |
|
Definition
|
|
Term
Where is a spermatocele palpable? |
|
Definition
near upper pole of the testicle |
|
|
Term
Is a spermatocele painful? |
|
Definition
|
|
Term
What is the treatment for a spermatocele? |
|
Definition
watchful waiting or surgery if it becomes symptomatic |
|
|
Term
What MUST any mass, in any pt, at any time felt to be in the testicle be addressed with? |
|
Definition
direct contact with a urologist. |
|
|
Term
Are masses rising from within the testes usually malignant or benign? |
|
Definition
|
|
Term
When a hydrocele is diagnosed, what must you perform and why? |
|
Definition
Perform complete testicular exam so don’t miss associated testicular tumor (10% of cases) |
|
|
Term
If varicocele is on the R side, enlarges quickly or remains dilated while pt is supine, what studies and evaluations must you perform? |
|
Definition
F/up with careful abdominal exam and appropriate imaging, such as CT scan |
|
|
Term
When is a surgery indicated for varicocele? |
|
Definition
needed if infertility or pain |
|
|
Term
If a pt c/o of heaviness in their testes, what might you suspect? |
|
Definition
Hydrocele or spermatocele |
|
|
Term
What condition is described as position of urethral meatus located on dorsal aspect of penis? |
|
Definition
|
|
Term
What may epispadias be associated with? |
|
Definition
|
|
Term
Which is more common epispadias or hypospadias? |
|
Definition
|
|
Term
What can increase the incidence of hypospadias? |
|
Definition
Estrogens and progestins given during pregnancy |
|
|
Term
What is hypospadias associated with? |
|
Definition
|
|
Term
When should hypospadias be surgically corrected? |
|
Definition
Should be surgically corrected by age 2 |
|
|
Term
At what gestational week can you determine the sex of the child based on viewable genitalia? |
|
Definition
|
|
Term
What condition is described as foreskin cannot be retracted behind the glans? |
|
Definition
|
|
Term
What is the MC cause of phimosis? |
|
Definition
Chronic infection from poor local hygeine |
|
|
Term
What type of CA can develop under the foreskin with phimosis? |
|
Definition
|
|
Term
What condition is an inflammation of the glans penis? |
|
Definition
|
|
Term
What condition is an inflammation of the foreskin? |
|
Definition
|
|
Term
What condition is described as the foreskin has been left retracted behind the glans, resulting in painful engorgement and edema of glans? |
|
Definition
|
|
Term
What are the complications of untreated paraphimosis? |
|
Definition
may result in glandular ischemia with arterial occlusion and necrosis of the glans |
|
|
Term
How should paraphimosis be tx initially? |
|
Definition
Firmly squeeze glans x 5 minutes to reduce tissue edema/decrease size. |
|
|
Term
What is the definitive treatment for paraphimosis? |
|
Definition
|
|
Term
What condition is described as palpable dense, fibrous plaque of varying size involving tunica albuginea? |
|
Definition
|
|
Term
Where is the usual location of the plaque in Peyronie's disease? |
|
Definition
usually near dorsal midline on the tunica albuginea |
|
|
Term
What condition has Peyronie's disease been associated with? |
|
Definition
Dupuytren’s contracture of the tendons of the hand |
|
|
Term
What is the only proven tx option for peyronie's disease? |
|
Definition
|
|
Term
In what % of pts does spontaneous remission of Peyronie's disease occur? When did this occur? |
|
Definition
|
|
Term
What condition is described as Uncommon condition of prolonged painful erection…”greater than 4 hrs”? |
|
Definition
|
|
Term
What is the MC cause of Priapism? |
|
Definition
|
|
Term
What other conditions are associated with causing Priapism? |
|
Definition
Leukemia Sickle Cell Dz Pelvic Tumors Pelvic Infections Penile Trauma Spinal Cord Trauma Certain Meds |
|
|
Term
Is priapism ischemic or non-ischemic? |
|
Definition
true urologic emergency (ischemic) |
|
|
Term
Should Hypospadiac males be circumcised? why or Why not? |
|
Definition
should not be circumcised because skin will later be needed for reconstructive surgery |
|
|
Term
How do you treat a fungal cause of phimosis? |
|
Definition
|
|
Term
How do you treat a bacterial cause of phimosis? |
|
Definition
bacitracin or neomycin-polymyxin B-bacitracin |
|
|
Term
How do you treat a dermatitis cause of phimosis? |
|
Definition
|
|
Term
What imaging test would you use to identify the depth of the plaque in peyronie's disease? |
|
Definition
|
|
Term
What condition has pathophysiology described as The major abnormality is believed to be physiologic obstruction of the venous drainage causing buildup of highly viscous, poorly oxygenated blood within the corpora cavernosa? |
|
Definition
|
|
Term
What condition is described as is a noncancerous enlargement of the prostate gland that may restrict flow of urine from the bladder? |
|
Definition
|
|
Term
What diagnosis is a histologic diagnosis that refers to the proliferation of smooth muscles and epithelial cells within the prostatic transition zone? |
|
Definition
|
|
Term
What is the MC benign tumor in men? |
|
Definition
|
|
Term
What is the medical management treatment for BPH symptoms? |
|
Definition
Alpha-blocker Therapy decreases tone of the Prostate which decreases resistance |
|
|
Term
What are the irritative voiding c/o BPH due to? |
|
Definition
result from the secondary response of the bladder to the increased outlet resistance |
|
|
Term
What are the 3 storage "irritative" symptoms of BPH? |
|
Definition
1- frequency, 2 - nocturia, 3 - urgency |
|
|
Term
What are the four voiding symptoms of BPH? |
|
Definition
1 - feeling of incomplete emptying, 2- intermittency, 3 - straining, 4 - weak stream |
|
|
Term
What is the most important tool in evaluate BPH? |
|
Definition
AUASI (BPH screening tool) |
|
|
Term
On DRE you find the prostate is smooth, firm, elastic with enlargement noted. What does this finding suggest? If induration was present, what would you do? |
|
Definition
BPH; with induration r/o CA |
|
|
Term
What procedure is Not recommended to determine the need for tx in BPH but may assist in determining the surgical approach in pts opting for invasive therapy? |
|
Definition
|
|
Term
What tx should pts with mild sx of BPH receive? |
|
Definition
Watchful Waiting; recommend annual f/u |
|
|
Term
What tx should pts with moderate sx of BPH receive? |
|
Definition
Start medical therapy - Alpha Blockers |
|
|
Term
What tx should pts with severe s/s of obstructive uropathy and fluid/electrolyte abnormalities receive? |
|
Definition
|
|
Term
What are the absolute surgical indications for BPH? |
|
Definition
refractory urinary retention, large bladder diverticula
Recurrent UTI Recurrent gross hematuria Bladder stones Renal insufficiency |
|
|
Term
Which drugs are alpha blockers? |
|
Definition
Tamsulosin (Flomax) Alfuzosin (Uroxatral) Doxazosin (Cardura) Terazosin (Hytrin) Silodosin (Rapaflo) |
|
|
Term
What are the side effects of Alpha Blockers? |
|
Definition
Orthostatic hypotension Ejaculation changes Nasal congestion Weakness |
|
|
Term
What medical therapy is best for pts with larger prostates (>40gm)? |
|
Definition
5 alpha-reductase inhibitors |
|
|
Term
What med works by blocking the conversion of testosterone to dihydrotestosterone? |
|
Definition
5 alpha-reductase inhibitors |
|
|
Term
Which drugs are 5 alpha-reductase inhibitors? |
|
Definition
Finasteride (Proscar) Dutasteride (Avodart) |
|
|
Term
What are the SE of the 5 alpha-reductase inhibitors? |
|
Definition
Decreased libido Ejaculation changes Erectile dysfunction |
|
|
Term
What meds act by decreasing acetylcholine effects on the smooth muscles of the bladder? |
|
Definition
|
|
Term
What are the Antimuscarinics? What drugs are they used in combo with? |
|
Definition
tolterodine, Detrol (esp. in combination with alpha blockers) |
|
|
Term
What minimally invasive procedure is described as 2 curved needles (which extend just beyond cystoscope) deliver RF energy into prostate? How long can the irritative voiding last after the procedure? |
|
Definition
TUNA (Transurethral Needle Ablation); can last several weeks after procedure |
|
|
Term
What procedure for treating BPH is described as Microwaves heat prostate and create thermal necrosis? How long can irritative voiding last after the procedure? |
|
Definition
TUMT (Transurethral Microwave Thermotherapy); irritative voiding can last for a few weeks after the procedure |
|
|
Term
Out of the minimally invasive procedures for treating BPH is the most superior when comparing symptom scores and flow rate improvement ? |
|
Definition
Transurethral resection of the prostate (TURP) |
|
|
Term
What is the alternative to TURP that comes closest to matching its results in both terms of symptom relief and improvement in flow rates? |
|
Definition
Transurethral Incision of the Prostate (TUIP) |
|
|
Term
When is an open simple prostatectomy used instead of a TURP? |
|
Definition
When prostate is too large to remove endoscopically (> 100 g in size) |
|
|
Term
At the following ages, what is their risk for BPH? 41 - 50 y/o? 51 - 60 y/o? > 80 y/o? |
|
Definition
41-50 yrs = 20% 51-60 yrs = 50% >80 yrs = >90% |
|
|
Term
What score on the AUASI indicates Mild, Moderate and Severe BPH symptoms? |
|
Definition
1-7, Mild 8-19, Moderate 20-35, Severe |
|
|
Term
What are the forms of Phytotherapy? |
|
Definition
Saw palmetto African plum Rye pollen Pumpkin seeds |
|
|
Term
What neurotransmitters initiate an erection? |
|
Definition
nitric oxide, acetylcholine, prostaglandins |
|
|
Term
What are some organic causes of ED? |
|
Definition
|
|
Term
What are some endocrine causes of ED? |
|
Definition
hypogonadism hyperthyroidism Elevated PRL |
|
|
Term
What are some neurologic causes of ED? |
|
Definition
spinal cord lesions MS autonomic neuropathy |
|
|
Term
What are some pelvic surgery causes of ED? |
|
Definition
bladder neck TURP (Prostate) |
|
|
Term
What drugs can induce ED? |
|
Definition
Antihypertensives (beta-blockers and diuretics), digoxin, major tranquilizers, alcohol, estrogen, antidepressants, cimetidine, steroids |
|
|
Term
What are the risk factor's for ED? |
|
Definition
Age > 40y/o DM, Dyslipidemia, HTN Neurogenic Dz Psychological Dz Renal Failure Hormonal D/o Previous Prostate CA tx Previous Trauma Drug Use, Smokers, Alcoholics Obesity, Sedentary Lifestyle |
|
|
Term
Which meds can lead to ED? |
|
Definition
Anti-HTN (BB, Thiazide Diuretics, Spirinolacton, Clonidine) Prostate Agents (Alpha Blockers- Doxyzosin, Terazosin, 5-alpha reductase inhibitors) Anti-Depressants - Cimetidine, Ketaconazole |
|
|
Term
What is Nocturnal penile tumescence testing used for? |
|
Definition
To differentiate between organic and psychological cause |
|
|
Term
What will men who do not have organic dysfunction causing their ED probably benefit from? |
|
Definition
behaviorally oriented sex therapy |
|
|
Term
Before giving hormone replacement therapy for documented androgen deficiency, what must you r/o first? |
|
Definition
|
|
Term
What class of meds is used in vasoactive therapy for the treatment of ED? |
|
Definition
prostaglandins (Papaverine, Phentolamine, Alprostadil) |
|
|
Term
What med is used for tranurethral therapy? |
|
Definition
Alprostadil (MUSE) - Prostaglandin |
|
|
Term
What med stimulates adenyl cyclase to increase intracellular levels of cAMP causing smooth-muscle relaxation and vasodilation? |
|
Definition
Alprostadil (Prostaglandin E1) |
|
|
Term
How does Sildenafil (Viagra) work? |
|
Definition
inhibits phosphodiesterase 5 (an inhibitor of erection) and allows cGMP to function unopposed |
|
|
Term
When is sildenafil (viagra) contraindicated? |
|
Definition
Concomitant organic nitrates or nitric oxide donors (eg, sodium nitroprusside) |
|
|
Term
What can coconmittant use of alpha-blockers (eg doxyzosin) and Sildenafil lead to? |
|
Definition
may lead to symptomatic hypotension. |
|
|
Term
How many viagra (sildenafil) do you take per day? |
|
Definition
|
|
Term
How long does sildenafil (viagra) last? |
|
Definition
|
|
Term
How long does Vardenafil (Levitra) last? |
|
Definition
|
|
Term
How often do you take Cialis (Tadalafil)? |
|
Definition
|
|
Term
What is the rate of onset with Cialis? How long does it last? |
|
Definition
Onset within 30 - 60 min; Lasts 36hrs |
|
|
Term
What is the max amount of time for use for Yohimbine? |
|
Definition
|
|
Term
What are the adverse effects of PDE-5 Inhibitor? |
|
Definition
Hypotension Temporary color vision disturbances Mild HA Facial flushing Priapism |
|
|
Term
What are the contraindications of PDE-5 Inhibitor? |
|
Definition
Men using nitrates, men on alpha-blockers |
|
|
Term
Which alpha-blocker is ok to use with PDE-5 Inhibitor? |
|
Definition
Flomax (tamsulosin) with Cialis |
|
|
Term
What are the relative contraindications for PDE-5 Inhibitors? |
|
Definition
Active coronary ischemia in men not on nitrates CHF Borderline hypotension, or on mult. HTN agents P450 - 3A4 inhibitors (E-mycin, cimetidine, Ketaconazole, Itraconazole) |
|
|
Term
What lifestyle changes may help improve ED? |
|
Definition
Regular exercise Healthy diet Smoking cessation Decrease alcohol intake Limit long-distance cycling…or change seat |
|
|
Term
In what pts is urinary incontinence MC? |
|
Definition
|
|
Term
Is the bladder neck muscle smooth or skeletal? Voluntary or Involuntary? |
|
Definition
Bladder Neck = smooth and involuntary |
|
|
Term
Is the external sphincter muscle smooth or skeletal? Voluntary or Involuntary? |
|
Definition
External Sphincter = skeletal and Voluntary |
|
|
Term
What test can be used to dx a bladder fistula? |
|
Definition
|
|
Term
What test can be used to diagnose bladder neck descent problems? |
|
Definition
|
|
Term
What test is used to evaluate bladder capacity, accommodation, sensation, voluntary control, contractility, and response to pharmacologic intervention? |
|
Definition
|
|
Term
What condition is described as Pts lose urine at all times and in all positions? |
|
Definition
|
|
Term
What is the cause of total urinary incontinence? |
|
Definition
anatomic abnormalities, either congenital or acquired |
|
|
Term
What is the treatment for total urinary incontinence? |
|
Definition
|
|
Term
What condition is described as loss of urine associated with activities that result in an increase in intra-abdominal pressure? |
|
Definition
|
|
Term
What is the cause of stress incontinence? |
|
Definition
Associated with pelvic floor laxity and poor support of the vesicourethral sphincteric unit |
|
|
Term
Which urinary incontinence does not have pts becoming incontinent in the supine position? |
|
Definition
|
|
Term
What are the findings of stress incontinence on a lateral stress cystogram? |
|
Definition
Bladder neck will descend below the midportion of the pubic symphysis |
|
|
Term
What treatment offers the best results and highest cure rates for stress incontinence? |
|
Definition
|
|
Term
What condition is described as uncontrolled loss of urine that is preceded by a strong, unexpected urge to void? |
|
Definition
|
|
Term
Which type of incontinence is unrelated to position or activity? |
|
Definition
|
|
Term
What condition is associated with detrusor hyperreflexia or sphincteric dysfunction? |
|
Definition
|
|
Term
What conditions are commonly associated with urge incontinence? |
|
Definition
Inflammatory conditions or neurogenic bladder d/o |
|
|
Term
What is the treatment for urge incontinence? |
|
Definition
Toilet Re-Training Anticholinergic meds (antispasmotics) - Oxybutinin (Ditropan) - Tolterodine (Detrol) Tricylic antidepressants - Imipramine (Tofranil) |
|
|
Term
What incontinence can result from chronic urinary retention? |
|
Definition
|
|
Term
What is the tx for overflow incontinence? |
|
Definition
catheterization and tx of underlying condition (cause of retention) |
|
|
Term
What percentage of men > 65y/o are affected by ED? |
|
Definition
|
|
Term
What nervous stimulation is responsible for an erection? |
|
Definition
autonomic and somatic nerve supply |
|
|
Term
Which arteries supply blood to get an erection? |
|
Definition
|
|
Term
What does an erection with injection of vasoactive substances mean? |
|
Definition
vascular system is intact |
|
|
Term
In pts who fail to achieve erection with injection of vasoactive substances on serial attempts using increasing doses or combination of drugs, what is indicated? |
|
Definition
Additional vascular testing and vascular reconstructive surgery in an attempt to correct their ED |
|
|
Term
What is considered infertility? |
|
Definition
Failure to conceive after 1 yr of trying |
|
|
Term
How many couples are affected by infertility? |
|
Definition
|
|
Term
What are the "cornerstones" to lab eval of infertility after H&P? |
|
Definition
Endocrinologic profiles and detailed semen analysis |
|
|
Term
What is the term describing Presence of < 20 million sperm/ml in the ejaculate? |
|
Definition
|
|
Term
What term describes Complete absence of sperm? |
|
Definition
|
|
Term
If there is a complete absence of sperm, what condition might you first suspect? How would you dx it? |
|
Definition
retrograde ejaculation; UA |
|
|
Term
How long does spermatogenesis take? |
|
Definition
|
|
Term
What prior testicular insults can lead to infertility? |
|
Definition
testicular torsion, cryptorchidism, trauma, groin surgery |
|
|
Term
What infections can lead to infertility? |
|
Definition
Mumps orchitis, epididymitis |
|
|
Term
What meds can lead to infertility? |
|
Definition
Cimetidine, spironolactone, nitrofurantoin, sulfasalazine, alpha-blockers (Cimetidine) |
|
|
Term
What are the risk factors for infertility? |
|
Definition
Sexual habits Previous fertility (pt and partner) Partner age (>35?) Endocrine d/o Systemic dz (renal failure, cirrhosis, sickle cell) Other dz (CF, Klinefelter’s) Poor dietary intake |
|
|
Term
What may be a finding in s/p viral orchitis causing infertility? |
|
Definition
|
|
Term
How many hours must a pt getting a semen analysis abstain from sex prior to the test? |
|
Definition
|
|
Term
What is the normal sperm count? |
|
Definition
|
|
Term
Within what timeframe of collection should the semen be analyzed? |
|
Definition
|
|
Term
What is the normal volume of semen? |
|
Definition
Normal volume = 1.5 – 5 ml |
|
|
Term
What is the normal motility of sperm? |
|
Definition
|
|
Term
What is the normal morphology? |
|
Definition
|
|
Term
What is the best predictor of fertility in semen? |
|
Definition
|
|
Term
If sperm counts are low, what further eval is indicated? |
|
Definition
Endocrinologic eval including serum FSH, LH, and testosterone |
|
|
Term
If the sperm count is zero, what f/u should be done? |
|
Definition
Serum FSH, fructose, testicular biopsy and U/A |
|
|
Term
If there is an abnormal sperm count, what is the f/u? |
|
Definition
repeat semen analysis …repeat semen analysis |
|
|
Term
How much time between repeat semen analysis? |
|
Definition
separated by at least 60 days |
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Term
What imaging can be done during an infertility eval to r/o subclinical varicocele? |
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Definition
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Term
What imaging study may be required in pts with suspected ductal obstruction? |
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Definition
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Term
What is the “gold standard” procedure for diagnosing pelvic, inguinal, scrotal, and vasal obstruction? |
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Definition
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Term
What is vasography being replaced by? |
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Definition
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Term
What is the MC neoplasm in men aged 20-35? |
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Definition
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Term
What is the 'typical' presentation of testicular CA? |
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Definition
pt-identified painless mass |
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Term
What is necessary for dx of testicular CA? |
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Definition
Orchiectomy necessary for dx |
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Term
What type of tumors are 90-95% of all primary testicular tumors? |
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Definition
germ cell tumors - arising from spermatogenic cells within seminiferous tubules |
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Term
Which testes is MC affected by testicular CA? Why? |
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Definition
right side, which parallels increased incidence of cryptorchidism on the right side |
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Term
What are the risk factors for testicular CA? |
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Definition
Cryptorchidism Testicular trauma, torsion Infection-related testicular atrophy Chemical exposures/pollutants |
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Term
Which imaging study can readily determine whether mass is intra or extratesticular in origin? |
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Definition
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Term
What biochemical markers can be pos in testicular CA? |
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Definition
Human chorionic gonadotropin (hCG) Alpha-fetoprotein Lactate dehydrogenase (LDH) |
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Term
Once dx of testicular cancer has been established by inguinal orchiectomy, how is clinical staging of the dz is accomplished? |
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Definition
accomplished by chest, abdominal, and pelvic CT scanning |
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Term
What is the MC testis tumor in pts > 50 y/o? |
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Definition
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Term
What is the MC primary site of CA with secondary metastasis to testes? |
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Definition
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Term
What are the essentials of diagnosis in bladder CA? |
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Definition
Irritative Voiding Symptoms Hematuria Pos Cytology Filing defect within bladder |
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Term
What is the 2nd MC GU CA? |
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Definition
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Term
Is bladder CA more common in men or women? |
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Definition
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Term
What is the mean age of pts when diagnosed with bladder CA? |
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Definition
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Term
What is a risk factor for bladder CA? |
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Definition
#1 - Smoking Chronic cystitis |
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Term
What is the MC presenting symptom in bladder CA? |
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Definition
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Term
What is the FDA approved screening test for bladder CA used in high risk pts? |
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Definition
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Term
How is bladder CA confirmed? |
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Definition
cystoscopy with bx (after obtaining urinary cytology) |
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Term
What is the initial form of tx for all bladder CA that is diagnostic, allows for staging, and will control superficial cancers? |
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Definition
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Term
What treatment is described as Immuno or chemotherapeutic agents delivered directly into bladder by a urethral catheter? |
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Definition
Intravesical chemotherapy |
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Term
What is used to treat metastatic bladder CA? |
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Definition
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Term
What is the "classic triad" of symptoms in renal cell carcinoma? |
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Definition
flank mass, hematuria, and pain |
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Term
What is the origination of renal cell carcinoma? |
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Definition
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Term
What is the peak age of incidence for renal cell carcinoma? |
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Definition
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Term
What percentage of pts already have metastasis with initial presentation of renal cell carcinoma? |
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Definition
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Term
What is a major RF for renal cell carcinoma? What are some other RF? |
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Definition
Cigarette Smoking;FHx, horseshoe kidney, acquired renal cystic dz, obesity |
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Term
What is the MC presentation of renal cell carcinoma? |
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Definition
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Term
What is the most valuable imaging test for renal cell carcinoma? |
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Definition
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Term
What is the primary treatment for localized renal cell carcinoma? |
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Definition
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Term
What is the 5-yr dz-free survival of Tumors confined to renal capsule? |
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Definition
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Term
What is the 5-yr dz-free survival of Tumors extending beyond the renal capsule? |
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Definition
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Term
What is the 5-yr dz-free survival of node-positive tumors? |
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Definition
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Term
What is the MC solid renal tumor of childhood? |
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Definition
Wilms tumor or nephroblastoma |
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Term
With Wilm's tumor, what is the peak age of onset? |
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Definition
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Term
What condition is described as unilateral generally large, multilobulated, kidney tumor that is gray or tan in color with focal areas of hemorrhage and necrosis? |
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Definition
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Term
What are the #1 and #2 sites of metastasis of a Wilms Tumor? |
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Definition
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Term
What is the MC presentation of Wilms tumor? |
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Definition
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Term
What is the tx for Wilms tumor? |
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Definition
Multimodal approach to tx, incorporating surgery, radiation therapy, and chemotherapy |
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Term
What is the second leading cause of CA related death? |
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Definition
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|
Term
What are the RF for prostate CA? |
|
Definition
Aging African American FHx positive for prostate cancer High fat intake (primarily a dz of the overfed) Toxic exposures (smoking, welding, agent orange) |
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Term
Where does CA of the prostate metastasize to? |
|
Definition
Bone, bladder and less commonly the testes |
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Term
What is found on DRE in prostate CA? |
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Definition
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Term
What complication may locally advanced dz of the prostate with bulky regional LAD lead to? |
|
Definition
lymphedema of lower extremities |
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Term
What marker is a glycoprotein produced only in the cytoplasm of benign and malignant prostate cells? |
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Definition
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|
Term
What PSA level are most organ-confined cancers are assoc with? |
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Definition
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Term
What PSA level are more advanced dz including seminal vesicle invasion, lymph node involvement, or occult distant mets associated with? |
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Definition
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Term
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Definition
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Term
What imaging study has been used largely in staging prostate CA? |
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Definition
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Term
What is the normal PSA value for white males ages: 40 - 49? 50 - 59? 60 - 69? 70 - 79? |
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Definition
40 - 49 = <2.5 50 - 59 = <3.5 60 - 69 = <4.5 70 - 79 = <6.5 |
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Term
What is the normal PSA value for AA males ages: 40 - 49? 50 - 59? 60 - 69? 70 - 79? |
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Definition
40 - 49 = <2 50 - 59 = <4 60 - 69 = <4.5 70 -79 = <5.5 |
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|
Term
What rate of change in PSA is linked to an increased likelihood of CA? |
|
Definition
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|
Term
What type of CA are the majority of prostate CA? |
|
Definition
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|
Term
What grading system is used with prostate CA? |
|
Definition
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|
Term
What is the tx for prostate CA? |
|
Definition
radiation and radical prostatectomy |
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|
Term
What continents are most affected by penile CA? |
|
Definition
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|
Term
What are the RF for penile CA? |
|
Definition
Poor Hygeine Uncircumcised |
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|
Term
At what age is penile CA MC? |
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Definition
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|
Term
What may penile CA begin as? |
|
Definition
Leukoplakia or condylomata lesion |
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|
Term
If velvety red lesion on penis, what condition do you suspect? |
|
Definition
Bowen dz (carcinoma in situ) |
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|
Term
What is the MC site of penile CA? |
|
Definition
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|
Term
What is the MC type of penile CA? |
|
Definition
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|
Term
What is mandatory in the treatment of penile CA? |
|
Definition
biopsy to r/o benign conditions (syphilis, condylomata or chancroid) |
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Term
What is the treatment for a primary lesion in penile CA? |
|
Definition
Fluorouracil (Effudex) cream 5% or laser tx |
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|
Term
What is the treatment for a invasive penile CA? |
|
Definition
Complete excision with adequate margins Complete penectomy if involves shaft |
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|
Term
Where does penile CA primarily spread? |
|
Definition
Spreads primarily to inguinal lymph nodes |
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|
Term
What is the tx for inoperable penila CA and bulky inguinal mets? |
|
Definition
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|
Term
What is the 5 yr survival rate for penile CA for pts with node negative dz? |
|
Definition
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|
Term
What is the 5 yr survival rate for penile CA for pts with pos inguinal nodes? |
|
Definition
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|
Term
What muscle is part of the spermatic cord? |
|
Definition
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|
Term
Where is the hydrocele located? |
|
Definition
between the two layers of tunica vaginalis |
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|
Term
What side is a varicocele MC found on? |
|
Definition
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|
Term
What side of the penis is a hypospadias on? |
|
Definition
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|
Term
What side of the penis is a epispadias on? |
|
Definition
|
|
Term
What side of the penis is a epispadias on? |
|
Definition
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