Term
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Definition
| Complication of clotting alteration |
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Term
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Definition
| Inherited bleeding disorder |
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Term
| Immune Thrombocytopenia Purpura (ITP) |
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Definition
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Term
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Definition
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Term
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Definition
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Term
Streptokinase (Streptase)
Alteplase (t-Pa) |
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Definition
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Term
Lepirudin
Desirudin
Argatroban |
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Definition
| Direct Thrombin Inhibitors |
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Term
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Definition
| Medication for von Willebrand Disease |
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Term
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Definition
| Refers to a physiologic process in which the blood is converted from a liquid state to semisolid gel. |
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Term
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Definition
| A blood clot formed in situ within the vascular system of the body and impeding blood flow. |
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Term
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Definition
| A blood clot, air bubble, piece of fatty deposit, or other object tht has been carried in the bloodstream to lodge in a vessel and cause an embolism. |
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Term
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Definition
| Deficiency of platelets in the blood. This causes bleeding into the tissues, bruising, and slow blood clotting after injury. |
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Term
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Definition
| An abnormally incrased concentration of hemoglobin in the blood, through either reduction of plasma volume or increase in red cell numbers. |
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Term
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Definition
| A discoloration of the skin resulting from bleeding underneath, typically caused by bruising. |
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Term
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Definition
| A small red or purple spot caused by bleeding into the skin. |
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Term
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Definition
| Bleeding in the knee joint. The most common caus of knee joint pain and knee joint swelling. |
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Term
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Definition
| The production of all types of blood cells including formation, development, and differentiation of blood cells. |
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Term
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Definition
| The stopping of a flow of blood. |
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Term
| Systemic Clotting Problem |
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Definition
| Problem extends to entire body; is usually the result of a significant hematologic event. |
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Term
| Localized Clotting Problem |
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Definition
| Problem is localized; is usually a problem in a vein or an artery, either injury to a vessel or a clot within a vessel. |
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Term
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Definition
| Damage to blood vessel has immediate reflex that promotes vasoconstriction, thus diminishing blood loss. Begins by forming a platelet plut by having platelets clump togehter, a process essential for blood clotting. |
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Term
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Definition
| Prevents over-enlargement of the fibrin clot. Limits size of blood clots by activating plasminogen to plasmin. |
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Term
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Definition
| Digests fibrin, fibrinogen, and prothrombin. |
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Term
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Definition
| Ecchymosis, petechiae, purpura, frequent nosebleeds, blood in stool, urine, emesis, bleeding gums, bleeding within joints, and excessive menstrual bleeding. |
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Term
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Definition
| Bleeding or ecchymosis at injury site, bleeding at surgical site, and intracranial bleeding. |
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Term
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Definition
| Substances that prevent or delay coagulation of the blood. |
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Term
| How do heparin and lovenox work? |
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Definition
| Inhibit clotting factors IIa (thrombin) and Xa |
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Term
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Definition
| Inhibits vitamin-K dependent clotting factors II, VII, IX, and X |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| 1.5 times the control (approx. 18 seconds) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| "Classic hemophilia" with a deficiency of factor VIII |
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Term
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Definition
| Also known as "Christmas disease" caused by deficiency of factor IX |
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Term
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Definition
| Deficiency of von Willebrand factor and factor VIII |
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Term
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Definition
| IV administration or nasal spray that causes 2-4 times' increase in factor VIII activity. Used for mild hemophilia. |
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Term
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Definition
| Prevents clot destruction |
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Term
Disseminated Intravascular Coagulation
(DIC) |
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Definition
| Disorder of coagulation that occurs as complication of numerous pathologic processes such as hypoxia, acidosis, shock, and endothelial damage. |
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