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Clin. Ther. Test 2
Mood Disorders
38
Medical
Graduate
03/16/2011

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Cards

Term
SIGECAPS
Definition
Sleep
Interest/Mood
Guilt
Energy
Concentration
Appetite
Psychomotor Agitation
Suicidal Ideations
Term
DIGFAST
Definition
Distractibility
Insomnia
Grandiosity
Flight of Thoughts
Activities
Speech
Thoughtlessness
Term
Tx for S.A.D?
Definition
1-2 hours of bright light daily
Term
Tx for psychotic depression?
Definition
ECT and antipsychotics
Term
What is the most common feature of psychotic depression?
Definition
Delusions
Term
What is the best tx for atypical depression?
Definition
MAOIs
Term
How can you prevent hypertensive crisis with MAOIs?
Definition
Tyramine free diet
Avoid SSRIs and TCAs
Term
Contraindications for TCAs?
Definition
Glaucoma
Urinary d/o
Cardiac
Term
Name some MAOIs.
Definition
Phenelzine(Nardil)
Tranylcypromine(Parnate)
Term
Name some TCAs.
Definition
Nortriptyline(Pamelor)
Amitriptyline(Elavil)
Clomipramine(Anafranil)
Imipramine(tofranil)
Doxepin
Term
Which TCA would you dose an elderly pt?
Definition
None if possible, but Nortriptyline - Start 25 qhs then titrate to 100 - 150 qhs
Term
TCA dosing for OCD?
Definition
Clomipramine(ANafranil) - 25-150qhs
Term
TCA that can also be used for Enurisis
Definition
Imipramine(Tofranil)
Term
What is a major side effect of SSRIs?
Definition
Sexual dysfunction
Term
What is the first SSRI of choice?
Definition
Lexapro(Escitalopram)
Celexa(Citalopram)
Term
Which SSRI is ok to use in Pregnant women?
Definition
Sertraline(Zoloft)
Term
SSRI for teens?
Definition
Fluoxetine(Prozac)
Term
SSRI for OCD?
Definition
Fluvoxamine(Luvox)
Term
What three meds can be used to replace SSRIs due to sexual dysfunction?
Definition
Bupropion, nefazadone, and mirtazipine
Term
What is the triad for Serotonin Syndrome? Tx?
Definition
Mental, autonomic, and neurologic. Dantrolene.
Term
What drug has a side effect of pripism?
Definition
Trazadone(Desryel)
Term
High seizure rate occurs with what med?
Definition
Bupropion doses above 450mg
Term
ECT is good for what dxs?
Definition
psychotic, refractory, or severe depression or refractory or life threatening mania.
Term
What do you not use within 10 days of lithium use?
Definition
ECT
Term
What are some objectives for antidepressant therapy?
Definition
May take 4 wks for meds to show effect.
Reach max dose before switching meds.
Be aware of side effect profile.
Taper over 1-2 wks.
Term
What should you rule out if 2 or more AD trials fail?
Definition
Hyperthyroidism
estrogen deficiency
sleep disorders
Term
1st line therapy for for acute severe manic or mixed bipolar.
Definition
-Lithium or Depakote and
-Antipsychotic
Term
For less sever bipolar what is a good tx?
Definition
Monotherapy-Lithium or antipsychotic (rispiradone)
Term
What should you monitor when on Lithium?
Definition
BUN/Cr
Term
What is special about the dosing of Venlafaxine?
Definition
<150mg acts on serotonin
>150mg acts on NE
Term
What 3 meds used for mood disorders are known to cause liver problems?
Definition
Cymbalta, Serzone, and Depakote
Term
Major Lamictal side effect.
Definition
SJS
Term
Major side effect for tegretol?
Definition
Agranulocytosis
Term
Two major side effects of Lithium?
Definition
DM and hypothyroidism
Term
Side effect of Trazadone (desryl)?
Definition
Priapism
Term
What is the advantage that Mirtazipine carries of other SNRIs and SSRIs?
Definition
Minimizes sexual dysfunction.
Term
All but what antipsychotic is FDA approved for tx of acute bipolar mania?
Definition
Clozapine.
Term
What are the extrpyramidal sxs that can occur with antipsychotics?
Definition
acute dystonia, akathesia, and pseudoparkinsonism
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