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Details

clinical pathology
anemia
49
Veterinary Medicine
Undergraduate 2
11/17/2011

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
what would it mean if the rbc indicies of the dog were normocytic;normochromic
Definition

it normal or acute blood loss, or non regenerative anemia

 

Term
what does it mean when the rbc indicies are microcytic;normochromic
Definition

it would be congenital in Akita and Shiba inus

( small cell normal color

Term
what does it mean when the cells are macrocytic and normochromic
Definition
congenital in poodle and Schnauzers meaning large cell normal color
Term
when a cell is normocytic but hypochromic what does it tell you
Definition
iron defieciency (slightly)
Term
when the cells are microcytic and hypochromic what does it tell you
Definition
iron deficiency
Term
what are two types of rbcs that you look for to conform iron deficiency after rbc indicies have been done
Definition
schistocytes, and keratocytes
Term
what can be a cause of low MCV
Definition
iron deficiency, or could b congenital in akitas and shiba inus
Term
what are causes of High Mcv
Definition
immature Rbcs or congenital in poodles and schnauzers
Term

true or false

macrocytosis may occur in anemic cats infected with FeLV

Definition
true feLv cats have larger rbcs high MCV
Term
what does it mean when the cell is macrocytic; hypochromic
Definition
regenerative anemia
Term
what is the cause of Low MCHC
Definition
iron deficiency
Term
what 3 things can trick the machine to read a high MCHC
Definition
hemolysis,lipemia, heinz bodies
Term

true or false

High MCHC would be considered an artifact

Definition
true; an rbc cannot have too much hb
Term
what is the best way to classify anemia
Definition
the bone marrow response
Term
what is the least accurate way to classify anemia
Definition
RBC indicies
Term
what is hypoxia
Definition
low oxygen in blood
Term
what is regenerative anemia
Definition
loosing blood abnormally but still producing rbc
Term
what is non regenerative anemia
Definition

loosing rbcs because of scenescent cells and kidney is not producing

loose blood without producing

Term

the absolute reticulocyte count verifies what type of anemia

 

Definition
Regenerative
Term
what are the two types of regenerative anemia
Definition

blood loss anemia

and

Hemolysis

Term

blood loss anemia can be         

hemorrhage or                      hemorrhage

Definition
acute or chronic
Term
what are the causes of acute hemorrhage
Definition
  • internal or external trauma;accidental or surgical
  • Coagulation disorders
  • Large ulcers or bleeding tumors
Term
what are causes of Chronic Hemorrhage
Definition
  • parasites
  • gi ulcers
  • inflammatory bowel disease
  • overuse of blood donors
Term
what  will you see in  regenerative anemia
Definition
anisocytosis and polychromasia
Term
An adult hookworm can take how much blood from a puppy in 24hrs
Definition
0.1mls
Term
in regenerative anemia how many hrs does it take a reticulocyte to appear
Definition
72
Term
name the 7 things that would cause hemolysis in the body
Definition

-immune mediated

-Blood parasites

- Heinz bodies

- other microorganisms

- water toxication

- hereditary rbc defects

- Metabloc diorder

Term

what can cause

Immune mediated hemolysis

IMHA

Definition
vaccine reaction,medication or drug, an infection or neoplasia
Term
what blood parasites cause hemolysis
Definition

haemobartonella canis

haemo felis

hemotropic myoplasma

babesia spp.

Cytauxzoon felis

Ehrlichia

Term

true or false

cats are more susceptible to Heinz bodies

Definition
true
Term
what organ sees heinz bodies as an abnormality and destroys through extravascular hemolysis
Definition
spleen
Term
what type of cell will you see when perfoming  a Comb's test
Definition
Spherocytes
Term
what causes heinz bodies
Definition

plants,

 onion and garlic toxitcity,

drug -acetaminophen,

 propylene glycol,

 zinc,

 copper,

propofol,

benzocaine,

napthalene,

Term
what is metabolic disorder
Definition
anything that interfers with synthesis of hb or anything that interferes with metabolic processes of RBC
Term
what are the two ways non regenerative anemia can occur 
Definition
  • Reduced erythropoises
  • Defective Erythropoieses
Term
name the infections that can cause harm to bone marrow causing non-regenerative anemia
Definition

FeLV

-FIV

-Parvovirus

-Ehrilichia

Term
what can cause reduced erythropoises causing non-reg. anemia
Definition
  • chronic disease
  • renal disease
  • damage to bone marrow
  • infectious agents
  • immune mediated causes
  • idiopathic aplastic anemia
  • congenital/inherited
  • myeloproliferative disorder
Term
how can the bone marrow be damaged
Definition
  • radiation
  • chemotherapeutic drugs
  • chloroaphenical(antibiotics)
  • other drugs
  • estrogen toxicity
Term
what are two ways that can cause defective erythropoieses leading to non-reg. anemia
Definition
  • disorded of heme synthesis

and

Abnormal Rbc maturation

Term
what can cause disorders of heme sythesis
Definition
  • copper,iron  vitamin B deficiency
  • Lead toxicity &
  • Some drugs
Term

true or false

idiopathic can cause abnormal Rbc maturation leading to non regeneratie anemia

Definition
true
Term
how long does it take for a aggregate reticulocyte to  mature into punctate reticulocyte in cats
Definition
12-24 hours
Term
how long can  punctate reticulocytes circulate in the cats body
Definition
7-10 days
Term

true or false

the more immature the cell the more RNA it contains

Definition
true
Term
what is the formula for the corrected reticulocyte
Definition
observed reticulocytes  x pvc/ normal pcv range
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