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Clinical Pathogy II
Exam #2
161
Veterinary Medicine
Undergraduate 3
04/03/2013

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Cards

Term
What 5 things should look for on the unstained side?
Definition
Casts, large crystals, clumps of cells, mucus threads, and debris
Term
What 2 things should you look for on 40x on the unstained side?
Definition
Bacteria and Brownian movement
Term
What 2 things should be recorded on the stained side on 10x?
Definition
Casts, clusters, and mucus threads
Term
What 9 things should be noted on the stained side on 40x?
Definition
RBCs, WBCs, Epithelial cells, crystals, sperm, debris, mucus threads, fat droplets, and microorganisms
Term
When would you see increased ketones?
Definition
Decreased carbohydrate and increased lipid metabolism
Term
What test pad is normal-to trace the answer?
Definition
Protein
Term
What is WBCs in urine called?
Definition
Pyuria
Term
What do granular casts in urine indicate?
Definition
Severe kidney disease
Term
What does intravascular hemolysis cause?
Definition
Hemaglobinuria
Term
What does bleeding in the lower urinary tract indicate?
Definition
Hemauria
Term
What does sweet/fruity scented urine odor indicate?
Definition
Diabetes mellitus and acetonemia in cattle
Term
T/F Bacteria should be present in normal urine.
Definition
False
Term
What are the 3 visual transparencies?
Definition
Clear, cloudy, flocculent
Term
What 4 things could cause increased specific gravity?
Definition
Dehydration, shock, acute renal disease, and decreased water intake
Term
What's increased frequency in urination?
Definition
Pollakiuria
Term
What is bilirubin that's bound to albumin?
Definition
Conjugated bilirubin
Term
What does pyuria indicate?
Definition
Inflammation in the urinary tract
Term
What's the most common cast?
Definition
Granular casts
Term
What is the oldest type of cast?
Definition
Hyaline casts
Term
T/F Some bilirubin is ok in cats.
Definition
False, ok in dogs
Term
What's ERD stand for?
Definition
Early Renal Disease/Detection
Term
What's increased amounts of uria in the blood?
Definition
Azotemia
Term
What does an increased BUN indicate?
Definition
An azotemic patient
Term
What does aa uremic patient indicate?
Definition
azotemic patient
Term
What are the 3 types of ketones?
Definition
Acetoacidic acid, acetone, and betahydroxyuric acid
Term
What type of bilirubin does the dipstick look for?
Definition
Term
Definition
Free bilirubin
Term
What 3 things can cause positive blood on a dipstick?
Definition
Hematuria, hemaglobinuria, and myeloglobin
Term
What 4 test pads are not reliable?
Definition
Nitrates, specific gravity, urobilogen, and leukocytes
Term
What are casts from youngest to oldest?
Definition
Granular, mixed, fine, waxy, hyaline
Term
What are the largest type of cast?
Definition
Waxy
Term
What are Dalmations famous for?
Definition
Ammonium biurate crystals
Term
What 2 things can an ERD test find?
Definition
Microalbumuria and early kidney damage
Term
What % of kidney damage must be gone before a BUN can detect it?
Definition
75%
Term
What is normal urine output?
Definition
20-40ml/kg/day or 1-2 ml/kg/hour
Term
What's the most common cause of cloudy urine?
Definition
Crystals and WBCs
Term
What should you watch closely for in diabetes?
Definition
Ketones
Term
What is a iatrogenic cause of crystalluria?
Definition
Sulfa drugs
Term
What is a cystocentesis?
Definition
Obtaining a urine sample through the bladder wall via a 22-gauge needle
Term
What are the 4 ways to collect urine?
Definition
Voided, cystocentesis, catheterization, and manual expression
Term
What is a calculus in the urinary tract?
Definition
Urolith
Term
What is frequent urination?
Definition
Polyuria
Term
T/F Odor pertains to the diagnostic evaluation of urine.
Definition
True
Term
What crystal is the most common in acidic urine?
Definition
Calcium oxalate dihydrate crystals
Term
What crystal is the most common in alkaline urine?
Definition
Triple phosphate/struvite crystals
Term
Why is the first morning urine sample preferred?
Definition
It's most concentrated in the morning
Term
What are things to look for in gross examination of urine?
Definition
Color, transparency, odor
Term
What 3 types of epithelial cells found in urine sediment?
Definition
Blood cells, squamous, and transitional
Term
What power should urine be examined on first?
Definition
10x
Term
What is specific gravity measured by?
Definition
Refractometer
Term
Where would sqaumous epithelial cells come from in urine sediment?
Definition
From the walls of the urethra
Term
Where would transitional epithelial cells come from in urine sediment?
Definition
From renal pelvis to urethra
Term
Why is a cystocentesis the best way to collect urine?
Definition
It's sterile
Term
Where are casts formed?
Definition
From the inside of the renal tubules
Term
What is blood that's present in amounts too small to be seen?
Definition
Occult blood
Term
How is occult blood detected?
Definition
Chemical analysis
Term
What does a large amount of foam in urine indicate?
Definition
Increased amounts of protein in the urine
Term
What do fat droplets look like in urine?
Definition
Water drops
Term
What do both types of calcium oxalate look like?
Definition
Monohydrate- Dumbell or pickett fence; dihydrate- envelope
Term
What is the advantage of using a refractometer over a urinometer?
Definition
They provide accurate S.G. with only a few drops of urine
Term
What do you need to be careful about when using urine reagent strips?
Definition
Not letting the test pads run together
Term
What should you check on the reagent strips before using and how do you store them?
Definition
The expiration date and make sure the strips are the same one as the bottle; store them in a cool, dry place, and with the lid tightly on
Term
What 6 test pads are wrote on a urinalysis?
Definition
Glucose, bilirubin, ketone, blood, protein, and urobilinogen
Term
What's included in the gross analysis?
Definition
Color
Term
What's the basic unit of the kidney?
Definition
Nephron
Term
What's the basic unit of the kidney?
Definition
Nephron
Term
How many nephrons do an avg. cat have?
Definition
200,000 per kidney
Term
How many nephrons do an avg. dog have?
Definition
700,000 per kidney
Term
What brings blood/waste products to the kidney?
Definition
Glomerulus
Term
T/F You should palpate a bladder after a cystocentesis.
Definition
False
Term
What are the 4 parts of a urinalysis?
Definition
Visual evaluation, specific gravity, chemical constituents, and microscopic sediment evaluation
Term
What type of bloody urine doesn't clear after centrifuging?
Definition
Hemaglobinuria or myouria
Term
What assesses renal tubules ability to concentrate urine or dilutes filtrates from the glomerulus?
Definition
Specific gravity
Term
What assesses renal tubules ability to concentrate urine or dilutes filtrates from the glomerulus?
Definition
Specific gravity
Term
Why do standing samples have higher readings of pH?
Definition
Loss of CO2 and urease-producing bacteria
Term
What test strip is measured in mg/dL?
Definition
Protein
Term
T/F Acidic urine causes false positive protein results.
Definition
False, alkaline
Term
What is the renal threshold for glucose?
Definition
170-180 mg/dL
Term
What ketone are test strips most sensitive to?
Definition
Acetoacetic acid
Term
Excessive amounts of what can cause CNS depression and acidosis?
Definition
Ketones
Term
Why does ketosis occur with diabetes mellitus?
Definition
Lack of insulin prevents carbohydrate breakdown
Term
What can cause a false negative for bilirubin?
Definition
light exposure
Term
What type of epithelial cells are most likely clumped
Definition
Transitional
Term
T/F Transitional cells are smaller than epithelial cells.
Definition
True
Term
What color cast are almost always stained light pink
Definition
Waxy
Term
What color are hyaline casts?
Definition
Nearly transparent or slightly pink with stain
Term
What type of cast can leptospirosis cause?
Definition
Epithelial cell cast (renal tubular epithelium sloughs)
Term
What's FUS?
Definition
Feline Urolith Syndrome
Term
What animals have tons of crystals in their urine?
Definition
Rabbits
Term
What type of urine can amorphous phosphates be found in?
Definition
Alkaline urine
Term
What crystals form in equine alkaline urine?
Definition
Calcium carbonate
Term
What type of urine are amorphous urates?
Definition
Acidic
Term
What type of urine are ammonium urates in?
Definition
Acidic
Term
What type of urine are bilirubin crystals in?
Definition
Acidic
Term
What type of urine are tyrosine crystals in?
Definition
Acidic urine
Term
What type of urine are cystine crystals in?
Definition
Acidic urine
Term
What type of urine are calcium oxalate crystals in?
Definition
Acidic
Term
What type of crystals will you only see in antifreeze toxicity?
Definition
Calcium oxalate monohydrate
Term
What crystals are thornapple or round and can appear as clusters of dumbbells?
Definition
Ammonium biurate
Term
What only brown crystal is found as rhombic plates or needles?
Definition
Bilirubin
Term
What crystals may appear black in the midsection and are rare?
Definition
Tyrosine
Term
What crystals are hexagonal plates that are flat?
Definition
Cystine
Term
What crystal are always flat squares with a notch out of the corner?
Definition
Cholesterol
Term
What 3 things should be noted in a gross evaluation?
Definition
Color, clarity, and flocculence
Term
T/F Hemaglobinuria has a clear red appearance.
Definition
True
Term
T/F Hemauria has a clear red appearance?
Definition
False, cloudy and red
Term
What cells are common when there's inflammation in the bladder?
Definition
Transitional epithelium
Term
What's the most common fungi found in urine?
Definition
Yeast
Term
What is larger than bacteria and can be confused with a RBC?
Definition
Fungi
Term
What 2 types of parasites can be found in urine?
Definition
Microfilaria and capillaria
Term
T/F Cellular casts are uncommon.
Definition
True
Term
What is a screening test/result for cushing's disease?
Definition
High Cortisol/creatinine
Term
What condition results from the buildup of toxins from vomiting and diarrhea (less fluids = lower glomerular filtration rate GFR)
Definition
Metabolic acidosis
Term
What're cells in the arterioles that stretch or shrink depending on BP?
Definition
Juxtaglomerular cells
Term
What does albumin in the urine indicate?
Definition
Early renal disease
Term
What is caused by decreased blood perfusion to the kidneys?
Definition
Prerenal azotemia
Term
What type of azotemia can they not concentrate urine?
Definition
Renal azotemia
Term
What type of azotemia is there a backflow of urine to the kidneys and ammonia goes in to bloodstream due to an obstruction?
Definition
Postrenal azotemia
Term
What does brown urine most likely contain?
Definition
Myoglobin
Term
What might be wrong with a pet if it has a high SG?
Definition
It might be dehydrated, have decreased water intake, have kidney disease, or be in shock
Term
What's the most common crystal seen in acidic urine?
Definition
Calcium oxalate dihydrate
Term
What's the most common crystal in alkaline urine?
Definition
Struvite/Triple Phosphate
Term
What does protein in the urine indicate?
Definition
Kidney disease
Term
What breed of dog has the most problems with crystals?
Definition
Dalmations
Term
What's the primary purpose of microscopic examination of the urine?
Definition
To look for things in sediment that could indicate disease
Term
Herbivores have acidic/alkaline urine?
Definition
Alkaline
Term
Isothenuria =
Definition
pH of 1.0
Term
Urine samples should centrifuged at?
Definition
Low speed (1000-3000 rpm) for 10 minutes
Term
What's the basic unit of the kidney?
Definition
Nephron
Term
What brings blood/waste products to the nephron?
Definition
Glomerulus
Term
What does microalbuminurua mean?
Definition
Low amounts of albumin in the urine
Term
Why can leaving a urine sample out cause higher pH values?
Definition
Loss of CO2 and urease-producing bacteria
Term
What's the renal threshold for a dog?
Definition
170-180 mL/d?
Term
What type of bilirubin is found in urine?
Definition
Conjugated
Term
What does a ERD test look for?
Definition
Early detections of renal disease
Term
What's the difference between amorphous phosphate and amorphous urates?
Definition
Amorphous phosphates are in alkaline urine and amorphous urates are in acidic urine
Term
What should urine be examined under first?
Definition
10x
Term
What's pH?
Definition
Hydrogen ion concentrate
Term
What do you look for in gross examination of urine?
Definition
Color, clarity, odor
Term
What's an uremic cat?
Definition
A cat with renal failure
Term
When do urea nitrogen levels increase in the blood?
Definition
Renal diseases, such as postrenal azotemia
Term
What's in aa blue top tube?
Definition
Sodium citrate (anticoagulant)
Term
What's in a tiger top tube?
Definition
Clotting and seruum separating gel
Term
Where is jaundice noticed 1st?
Definition
Eye sclera and roof of mouth
Term
What's the average SG of canine urine?
Definition
1.025
Term
What's the average SG of feline urine?
Definition
1.030
Term
hat type of urine can cause false positives on protein?
Definition
Alkaline only
Term
Excited, fearful, and stress can cause what?
Definition
Glucosuria
Term
What are produced during fat catabolism?
Definition
Ketones
Term
What is a byproduct of fat metabolism?
Definition
Ketones
Term
What can cause epithelial cell casts?
Definition
Leptospirosis
Term
What's only seen in antifreeze toxicity?
Definition
Calcium oxalate monohydrate
Term
What crystals have a thornapple shape?
Definition
Ammonium biurate
Term
What're 4 non-useful reagent pads?
Definition
SG, Nitrate, Leukocyte, Urobilinogen
Term
What % of blood is filtered per minute?
Definition
20%
Term
What cells (in arterioles) stretch or shrink depending on BP?
Definition
Juxtaglomerular cells
Term
What's the definiton of renal failure (azotemia)?
Definition
75% or more nephrons lost
Term
What type of azotemia is caused by decreased blood perfusion to kidneys? (Dehydration)
Definition
Prerenal azotemia
Term
What type of azotemia can they not concentrate urine?
Definition
Renal azotemia
Term
What type of azotemia is a rise in non-protein compounds due to urinary obstruction?
Definition
Postrenal azotemia
Term
What type of azotemia does urine backflow to the kidneys?
Definition
Postrenal azotemia
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