Term
What is the pathophysiology of GERD? |
|
Definition
Relaxation of gastroesophageal sphincter allowing reflux of gastric acid and pepsin into the esophagus |
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Term
What are the signs/symptoms of GERD? |
|
Definition
Dysphagia Heart Burn Increased Salivation Belching Pain radiating to jaw, neck, or back |
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Term
How can sphincter tone be improved (in GERD)? |
|
Definition
•Lose weight if necessary •Stop smoking •Determine if medicine may be the cause •Remain upright after eating •Wear loose-fitting clothes •Sleep with head slightly elevated |
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Term
Why is it important to control GERD? |
|
Definition
It can lead to Barret's Esophagus (Normal squamous cell epithelium of lower esophagus are changed to metaplastic columnar cell epithelium) and Esophageal adenocarcinoma |
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Term
What foods should be avoided to control GERD? |
|
Definition
Foods that impare sphincter pressure:Foods high in fat, chocolate, spearmint, peppermint, alcohol & caffeine Food that increase stomach acidity: Red & black pepper, coffee (caf. & decaf.), alcohol •Avoid large meals – consume smaller, more frequent meals instead |
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Term
Which supplements may be necessary in patients with GERD? |
|
Definition
•Long-term use of GERD meds can lead to calcium, iron & B12 deficiencies; so supplement these. |
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Term
How is GERD treated in infants? |
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Definition
Usually resolves within a year If due to allergy, remove allergen (may be in milk) Feed elevated and keep elevated 30 min. after feeding. |
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Term
What do you do if a patient presents with dysphagia? |
|
Definition
Refer to apporopriate provider accourding to clinical presentation |
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Term
What are some clear liquids & bland foods? |
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Definition
Clear liquids •Water •Apple juice •Sports drink •Tea •Lemonade •Chicken broth Bland foods •Dry toast •Crackers •Pretzels •Potato •Yogurt •Sherbet •Baked chicken |
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Term
What are the signs/symptoms of gastritis? |
|
Definition
Belching, weight loss, abdominal pain, vomiting & bleeding if severe |
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Term
What causes most peptic ulcers? |
|
Definition
H. pylori infection causes 70% of all gastric & 92% of all duodenal ulcers |
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Term
How are peptic ulcers treated? |
|
Definition
Peptic ulcer + H. pylori infection
7-14 days of 2 antibiotics
Proton pump inhibitor (PPI)
Peptic ulcer - H. pylori infection
Antacids
PPI
Histamine blockers
Mucosal protectors |
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Term
What is the nutrition therapy for peptic ulcers? |
|
Definition
Avoid foods that increase stomach acidity (pepper, coffee, alcohol, caffeine)
Avoid large meals (smaller, more frequent)Supplement Ca, Fe, B12 |
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Term
What is dumping syndrome? |
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Definition
•Food enters SI too fast, forcing fluid to be drawn into SI to dilute it •Causes nausea, vomiting, bloating, diarrhea •Early dumping = 10-20 min after eating •Intermediate dumping = 20-30 min after eating •Late dumping = 1-3 hr after eating |
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Term
Which supplements are indicated in bariatric surgery? |
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Definition
Most common deficiencies: •vitamins B12, A, C, D, K, thiamin, folate, iron, selenium, copper, zinc & calcium Take multivitamin/multimineral & supplements of: •Vitamin B12, iron, calcium, fat-soluble vitamins |
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Term
How often should nutrition levels be monitored in patients with geriatric surgery? |
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Definition
Nutrient levels should be monitored every 3 months |
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Term
What are the clinical manifestations of diarhea? |
|
Definition
Increased number of BM & decreased consistency of stools
Abdominal discomfort, dehydration, electrolyte imbalance, weight loss
Blood may be present |
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Term
What are the treatment protocols for acute, osmotic & secretory diarrhea? |
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Definition
Acute
Rest
Fluids
Osmotic
Avoid foods that cause (fatty foods, sorbitol)
Supplemental enzymes may be necessary Secretory
Treat underlying cause
Antibiotics
Remove & treat tumor |
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Term
What are some nutrition interventions for diarhea? |
|
Definition
Restore fluid/electrolyte balance
Try Pedialyte or Gatorade
Decrease GI motility
Avoid foods/beverages high in simple sugars, sugar alcohols, caffeine & alcohol
Thicken stools
Add soluble fiber
BRAT – bananas, rice, applesauce, toast Repopulate flora of LI
Probiotics & prebiotics |
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Term
What does BRAT stand for? |
|
Definition
BRAT – bananas, rice, applesauce, toast diet for thickening stools when someone has diarhea |
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Term
How is constipation defined? |
|
Definition
1. Average 1 or less bowel movements (BM)/week for at least 12 months. OR 2. Have at least 2 of the following for 12 weeks in the last year: 2 or less BM/week Straining during at least 25% of BM Hard stools during at least 25% of BM Sensation that not all fecal material is eliminated during at least 25% of BM |
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Term
What are the most common nutritional diagnoses that accompany constipation? |
|
Definition
Nutrition Diagnosis •Inadequate fiber intake •Inadequate food/beverage intake •Altered GI function •Undesirable food choices |
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Term
What nutrition interventions would you recommend for constipation? |
|
Definition
Recommended fiber intake = 10-13g/1000 Cal
Adult RDA = 25-35 g/d
Children RDA = age + 5g fiber/d
Slowly add 1-2 high-fiber foods/d
Increase fluid intake to 8-10 cups/d
Probiotics & prebiotics may also be beneficial |
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|
Term
What are the clinical manifestations of fat malabsorption? |
|
Definition
•Malnutrition •Altered GI function •Impaired nutrient utilization •Involuntary weight loss Symptoms •Abdominal pain •Cramping •Diarrhea •Stools are frothy, foul-smelling & greasy in appearance |
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|
Term
What are some causes of fat malabsorption? |
|
Definition
Steatorrhea
Inadequate pancreatic enzymes
Impaired bile release
Abnormal motility |
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|
Term
What nutritional intervention would be recommended for fat malabsorption? |
|
Definition
Restrict fat to 25-50g/d
Medium chain triglyceride supplements may be used to increase energy (C8 and C10 FA)
Supplement with pancreatic enzymes if necessary |
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|
Term
What is not digested/absorbed in carb malabsorption? |
|
Definition
Lactose intolerance •Inadequate lactase •Lactose is fermented in LI to SCFA & GAS |
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|
Term
How is it carb malabsorption treated? |
|
Definition
Lactose-free diet or supplement with lactase enzymes |
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|
Term
What compound causes an inflammatory response in Celiac disease? |
|
Definition
prolamins (alcohol-soluble part of protein found in wheat, rye, malt, barley & oats) damaging SI |
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|
Term
What is the etiology of celiac disease? |
|
Definition
•Genetic •HLA-DQ2 & HLA-DQ8 present in 95% of CD patients •Autoimmune •Intestinal damage causes antibody production •Environmental •Introduction of gluten too early •Less time breastfed •Viral infection in infancy |
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|
Term
When should gluten-containing foods be introduced to infants? |
|
Definition
After 3 months, before 7 months |
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|
Term
What are the clinical manifestations of CD? |
|
Definition
Diarrhea •Abdominal cramping •Bloating & gas •Bone & joint pain •Muscle cramps •Fatigue •Peripheral neuropathy •Seizures •Dermatitis herpetiformis •Mouth ulcerations |
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Term
|
Definition
•GOLD STANDARD = SI biopsy •More common •Anti-tissue translutaminase (anti-tTG) antibody •Sensitivity = 90-96% •Specificity = 95-97% •Endomysial IgA (EmA) antibody •Sensitivity = <90% •Specifity = 100% |
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|
Term
What nutrition intervention is performed following diagnosis of CD? |
|
Definition
Initially •Gluten-free, lactose-free diet |
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|
Term
What dietary measures are changed after 1-2 months following a CD diagnosis? |
|
Definition
Can reintroduce lactose!
Remain gluten-free for life |
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|
Term
What are some gluten-free options? |
|
Definition
•Amaranth •Arrowroot •Bean flours •Buckwheat •Corn •Fava •Flax •Nut flour •Oats (uncontaminated) •Pea flour •Potato •Quinoa •Rice •Sorghum •Soy •Tapioca <20 ppm of gluten can be labeled gluten-free! |
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|
Term
What is gluten sensitivity? How does it differ from Celiac’s? |
|
Definition
GI symptoms triggered by gluten Alleviated with gluten withdrawal Ruled out: CD, wheat allergy, Type 1 diabetes, inflammatory bowel disease & Helicobactor pylori infection No anti-gluten antibodies or genetic markers GI lesions may still be present, just not an autoimmune reaction Mechanism has not been elucidated |
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|
Term
What is the pathology of ulcerative colitis & Crohn’s? |
|
Definition
Ulcerative Colitis •Inflammation of the mucosa & submucosa •Involves rectum only in 50% of patients •Limited to colon only •Peak onset 20-30 years Crohn's •Inflammation of the mucosa •Mostly in ileum & colon •Peak onset teens to 20’s |
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|
Term
What differs between the symptoms & complications in Ulcerative Colitis and Crohn's? |
|
Definition
Ulcerative Colitis
Bloody, mucusy diarrhea
Abdominal/rectal pain
Fever
Weight loss
Possible constipation
Arthritis
Dermatitis
Ocular manifestations
Crohn's
Chronic diarrhea
Severe abdominal pain
Anorexia
Weight loss
Malnutrition
Fever
Growth retardation |
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|
Term
What diet & supplements should be recommended during an IBD (UC and Crohn's) flare? |
|
Definition
•MVM •B12 (Crohn’s; nasal gel or injection) •Zinc (12-15 mg/L stool output) •Calcium •Magnesium •Copper (0.5-1.5 mg/day) •Probiotics/Prebiotics |
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|
Term
What should be limited in the diet for IBD patients, even during remission? |
|
Definition
Limit foods high in oxalate (cocoa, tea, peanut butter, spinach, nuts, strawberries, tofu, backed beans, high dose vitamin C) |
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|
Term
What is the difference between IBS-D, IBS-C & IBS-M? |
|
Definition
IBS-D = diarrhea predominant IBS-C = constipation predominant IBS-M = mixed diarrhea & constipation |
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|
Term
What is the pathophysiology associated with IBS-D, IBS-C & IBS-M? |
|
Definition
Altered serotonin production •Serotonin causes release of: Acetylcholine = smooth muscle contraction Nitric oxide = smooth muscle relaxation •Serotonin reduced in IBS-C; increased in IBS-D |
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|
Term
What is the FODMAP restriction? |
|
Definition
Don't eat foods with Fermentable Oligo-, Di- and Mono-saccharides, and Polyols.
Helps with IBS |
|
|
Term
Should insoluble fiber be recommended to IBS patients? |
|
Definition
|
|
Term
How is diverticulosis treated? |
|
Definition
High fiber diet (25-35 g/day + 6-10 g extra) Fluids |
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|
Term
How is diverticulitis treated? |
|
Definition
Antibiotics Bed rest Liquid diet |
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|
Term
How much protein is required for alchoholic liver diseased patients? |
|
Definition
|
|
Term
What supplements are recommended for patients with alchoholic liver disease? |
|
Definition
Thiamin 50-100 mg for 7-14 days Folic acid 1000 mcg/day Riboflavin Amount in a multivitamin (MVM) B6 1-3 mg as part of a MVM B12 6-12 mg as part of a MVM C 175-500 mg/day A Amount in a MVM D 200-500 IU/day E 10-50 IU as part of a MVM Fe Standard amount in MVM for premenopausal women; Find a MVM without for men & postmenopausal women Mg 100-400 mg/d if deficiency suspected Se 5-50 mcg/day Zn Amount in MVM Supplements in Alcoholism Nelms |
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|
Term
What are the clinical manifestations of gall stones? |
|
Definition
may be asymptomatic Right quadrant pain |
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|
Term
What nutritional intervention would be recommended for gallstones? |
|
Definition
• Low fat diet (<30% Cal) •Moderate protein • Smaller, more frequent meals • Rest bowel with attacks •Water-soluble supplementation of ADEK may be necessary • After surgery, more fiber may be necessary |
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|
Term
What are some causes of kidney stones? |
|
Definition
Hypercalciuria, gout, excess vitamin D intake, UTI |
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|
Term
What nutritional intervention would be recommended for kidney stones? |
|
Definition
• Increase fluid intake by 3 L/d (at least 50% from water)
• Not necessary to limit dietary calcium (dairy can actually prevent kidney stones)
• Limit oxalate intake to 50-60 mg/d
• Avoid: beets, chocolate, cola, coffee/tea, nuts/nut butters, berries, wheat bran, spinach, rhubarb & high dose vitamin C
• For stones high in uric acid, avoid high purine foods |
|
|
Term
What are some high oxalate foods? |
|
Definition
cocoa, tea, peanut butter, spinach, nuts, strawberries, tofu, backed beans, high dose vitamin C |
|
|
Term
How is it type 1 diabetes diagnosed? |
|
Definition
Diagnosis (1 of the following) • Symptoms + blood glucose >200 mg/dL • Fasting plasma glucose >125 mg/dL • Plasma glucose >200 mg/dL after oral glucose tolerance test (OGTT) |
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|
Term
What % of energy should be coming from carbs, proteins & lipids? |
|
Definition
• Protein = 15-20% Cal • Lipids = 30% Cal • Carbs = 45-65% Cal |
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|
Term
What is the basis of carb counting? |
|
Definition
Best method of maintaining blood glu • Total intake of CHO intake, not source • Count starches, fruits, dairy, sweets • Nonstarchy veggies don’t need to be counted as long as <15 g CHO are not eaten |
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|
Term
Is exercise recommended for T1DM? |
|
Definition
|
|
Term
What are some short-term & long-term complications for T1DM? |
|
Definition
Short Term: hyperglycemia Ketoacidosis hypoglycemia Long Term CVD Nephropathy Retinopathy Peripheral neuropathy Autonomic neuropathy |
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|
Term
How is the pathology of T2DM different from T1DM? |
|
Definition
T2DM is insulin-independent |
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|
Term
What compound phosphorylates IRS-1? |
|
Definition
|
|
Term
What are some risk factors for type 2 diabetes? |
|
Definition
Genetics (<25 years) Obesity Physical inactivity High birth weight babies Low birth weight babies |
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|
Term
How much exercise is recommended for T2DM patients? |
|
Definition
30-45 min of mod. intensity exercise 3- 5 days/week Resistance exercise 3 days/week |
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|
Term
What nutrition therapy would be recommended for T2DM? |
|
Definition
Weight loss
Decrease caloric intake (1200-1600 Cal) Increase physical activity
Carbs
Get at least 130 g carbs per day
Carb counting is recommended
Protein
No more than 20% Cal/day
With nephritis, limit to 10% Cal/day
Fat
25-35% Cal
Limit saturated fat to ~7%, trans fat 0%
Fiber
Get 25-38 g/day from fruits, veggies, whole Fiber grains & legumes |
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|
Term
What supplements may be beneficial for T2DM? |
|
Definition
A • Alpha-lipoic acid • Konjac glucomannan B • Beta-glucan • Fenugreek • Ginseng • Gymnema •Magnesium • Vanadium • Whey protein |
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|
Term
What are some complications to gestational diabetes for the mother? |
|
Definition
• Hypertension (preeclampsia), excessive amniotic fluid, premature delivery, difficult birth, higher C-section rate |
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|
Term
What are some complications to gestational diabetes for the infant? |
|
Definition
Large for gestational age, hypoglycemia, respiratory distress, hypocalcemia, jaundice & polycythemia |
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|
Term
What are the recommendations for protein, fat, carbs & sodium in those with T3DM? |
|
Definition
Protein RDA = 1.1 g/kg of desirable BW Fat Limit saturated & trans fat Carbs Space throughout the day to avoid ketonuria Sodium Not restricted during pregnancy |
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|
Term
What is the difference between reactive & fasting hypoglycemia? |
|
Definition
Reactive hypoglycemia: diabetics that administer too much insulin
Fasting hypoglycemia: excess insulin or insulin-like substances (drugs, alcohol, etc.) |
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|
Term
How is hypoglycemia diagnosed? |
|
Definition
All three of the following must be present: 1. Low blood glucose (<70mg/dL) 2. Weakness, fatigue, sweating, palpitations 3.Symptoms disappear with carb ingestion & blood glucose returns to normal |
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|
Term
What nutrition therapy would be recommended for hypoglycemia? |
|
Definition
1. Small, frequent meals with complex carbs, fiber & protein 2. Avoid simple carbs & alcohol 3. Limit caffeine (reduces cerebral blood flow) |
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|
Term
Can goitrogens be consumed by hyper or hypothyroid patients? |
|
Definition
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|
Term
What nutrition therapy is recommended for hyper and hypothyroid patients? |
|
Definition
The only nutrition therapy for disorders of the thyroid & pituitary gland are to minimize food-drug interactions. |
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|
Term
Is adrenal insufficiency reversible? |
|
Definition
|
|
Term
How is adrenal insuficiency diagnosed? |
|
Definition
give a dose of ACTH & measure blood concentrations of cortisol |
|
|
Term
How is adrenal insuficiency treated? |
|
Definition
|
|
Term
Is chronic fatigue reversible? |
|
Definition
|
|
Term
How is chronic fatigue diagnosed? |
|
Definition
Low (unstimulated) saliva cortisol levels CAN be used to diagnose chronic fatigue syndrome |
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|
Term
How is Chronic Fatigue treated? |
|
Definition
Exercise, cognitive behavioral therapy |
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|
Term
What is the etiology of microcytic anemia |
|
Definition
Blood loss (menstruation, gastric ulcer) Inadequate Iron (intake or absorption) Infancy/Childhood (cows milk interferes with absorption, soy formula Must be iron fortified) Pregnancy Excess minerals (divalent) |
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|
Term
What are some health conditions associated with microcytic anemia? |
|
Definition
|
|
Term
What are the clinical manifestations of microcytic anemia? |
|
Definition
pallor, fatigue, cold extremities, malaise, tachycardia (HR >100 beats/min) |
|
|
Term
What are some biomarkers for microcytic anemia? |
|
Definition
|
|
Term
What are some strategies for increasing dietary & supplemental iron? |
|
Definition
Increase vitamin C Molasses Cast iron pans |
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|
Term
What else needs to be taken if iron supplements are indicated? |
|
Definition
Zn (Fe inhibits Zn absorption) |
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|
Term
What is the cause of regular megaloblastic vs. pernicious anemia? |
|
Definition
Megaloblastic caused by folate & B12 deficiencies pernicious a type of megaloblastic caused by atrophic gastritis or Autoimmune issue |
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|
Term
|
Definition
|
|
Term
What are folate & B12 required for in the body? |
|
Definition
Required for 1C metabolism (methylation) in rapidly dividing cells. |
|
|
Term
What are the clinical manifestations of megaloblastic anemia? |
|
Definition
pallor, fatigue, irritability, neuropathy if prolonged |
|
|
Term
What are some biomarkers for megaloblastic anemia? |
|
Definition
holotranscobalamin II or methymalonic acid (MMA) |
|
|
Term
How is megaloblastic anemia treated? |
|
Definition
•Limit carbonated soft drinks (associated with folate def.) •Increase folic acd & B12 fortified cereals •Be careful, folate repletion can mask a B12 deficiency! •Dietary interventions should be tried prior to supplementation •B12 supplements are made from cyanocobalimin – a weakly active B12 |
|
|
Term
What nutrition education would be important for Hemochromatosis? |
|
Definition
EDUCATION: heme vs. non-heme iron, vitamin C avoidance of cast-iron, MVM with iron & alcohol increase fiber, phytates & tannin consumption, limit meat |
|
|
Term
What deficiency is related to restless leg syndrome? |
|
Definition
iron deficiency or altered iron metabolism |
|
|
Term
How is restless leg syndrome treated? |
|
Definition
High dose supplementation is required Fe supplements >250 mg/dose, 2-3 times/day Take with vitamin C, separately from other mineral supplements |
|
|
Term
What diet is often prescribed for epilepsy? |
|
Definition
Ketogenic diets = high fat, low carb Classic Medium-chain triglyceride Low-glycemic index Modified Atkins diet |
|
|
Term
Is the ketogenic diet indicated for patients taking Topamax? |
|
Definition
will cause weight loss and kidney stones if combined |
|
|
Term
What macronutrient ratio is used in the classic version of the ketogenic diet? |
|
Definition
|
|
Term
What supplements are necessary for the ketogenic diet? |
|
Definition
Patients need to take a sugar-free multivitamin, calcium & vitamin D supplements |
|
|
Term
What are some risk factors of stroke that may be influenced by diet? |
|
Definition
HTN CCD Diabetes Dyslipidemia Obesity |
|
|
Term
What are some dietary measures that may reduce the risk of stroke? |
|
Definition
•Rich in fruits, veggies, nuts, soy & cereal fiber •More fish & poultry than red meat •More PUFA than SFA •Low in trans fat •Multivitamin use for >5 years |
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|
Term
|
Definition
|
|
Term
Should vitamin B6 supplements be given to a patient with Parkinson’s disease taking L-dopa? |
|
Definition
no, it speeds up the process of converting L-dopa to dopamine. |
|
|
Term
What are some dietary strategies to control GERD & constipation commonly seen in Parkinson’s? |
|
Definition
Encourage smaller, more frequent meals Low in fat & fiber |
|
|
Term
What is the etiology involved in MS? |
|
Definition
Genetics •Region on chromosome 6 encoding mutated interleukin receptors (IL7R & IL2RA) Environmental factors •Latitude – decreased vitamin D associated with MS •Smokers are 70% more likely to develop MS •Hygiene hypothesis – delayed exposure to certain viruses (Epstein-Barr virus) increases risk of MS |
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|
Term
What dietary restrictions & supplements are recommended in MS? |
|
Definition
Restriction of SFA
Omega-3 supplements
Supplementation of Ca & vitamin D (required with long-term corticosteroid use) |
|
|
Term
What is the etiology involved in Alzheimer’s disease? |
|
Definition
age genetics (mutation in apolipoprotein Ee4) Obesity, CVD, diabetes, free-radical catalyzed oxidation, Down syndrome, previous brain trauma |
|
|
Term
What dietary strategies can be employed to prevent Alzheimer’s? |
|
Definition
Caloric restriction (as 30% less E from carbs only) has been successful in preventing AD in animal models Decreased beta-amyloid plaque production Control blood glucose Normal blood pressure |
|
|
Term
Can the Mediterranean diet decrease the risk of Alzhemier’s? |
|
Definition
|
|
Term
What supplements may be beneficial in Alzheimer’s? |
|
Definition
•Liquid supplements are best •Under investigation in early stage AD: •omega-3 FA •B vitamins •vitamin C •vitamin E |
|
|
Term
What supplements may increase the risk of Alzheimer’s? |
|
Definition
Cu in older patients MVM condtaining Fe in older patients |
|
|
Term
What dietary strategies may be recommended to enhance food consumption by decreasing mealtime confusion in your Alzheimer’s patient? |
|
Definition
•offer 1 food at a time •use simple place setting •plate should be a different color than table •add condiments prior to serving •focus on finger foods •allow adequate eating time (30-45 min) •maximize food intake during lunch (cognition is usually best at this time) |
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|
Term
What is the major cause of traumatic brain injuries? Spinal cord injuries? |
|
Definition
Falls (28%), motor vehicle accidents (20%), ‘struck by/against’ (19%), firearms (11%), bike accidents (3%) |
|
|
Term
What caloric & protein recommendations are given for patients with brain or spinal cord injuries? |
|
Definition
Acute Energy intake should be 10% below predicted REE •Protein = 2.0 g/kg bw/day Rehab •paraplegic = 27.9 kcal/kg bw •quadraplegic = 22.7 kcal/kg bw •Protein = 0.8-1.0 g/kg bw/day |
|
|
Term
What supplements may be utilized for your patients with spinal cord injuries? |
|
Definition
Omega-3s may be beneficial for improved performance Vitamin D deficiency is very common in SCI patients |
|
|