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Clinical Neuro
Pathophsy: Neuroimmune diseases
12
Biology
Graduate
01/09/2008

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Cards

Term
Who is more likely to get MS?
Definition
the young and women
Term
Where in the world is MS more prevalent?
Definition
The further away you move from the equator
Term
Are very clean people more likely to develop MS?
Definition
yes
Term
Is MS familial?
Definition
yes
Term
What's the clinical presentation of MS
Definition
1. 40% of people present w/ somatosensory or motor disorders
2. 35% present w/ visual symptoms
Term
What's the most common type of MS?
Definition
Relapsing-remitting w/ or w/out accumulating disability
Term
Grossly how does MS manifest
Definition
Discolored patches in the brain and SC
Term
If you were looking at an MRI, were would you find MS plaques in the brain
Definition
Peri-ventricular areas, optic nerves
Term
Why do plaques manifest in MS?
Definition
Demylenination, axonal damage, gilosis and inflammation in the CNS
Term
What's the etiology of MS? Hint there is 4
Definition
1. Immune cell mediated damage
2. Humoral mediated damage
3. Degenerative pathology w/ apoptosis
4. Degenerative pathology w/ necrosis
Term
APC actives ______ which causes the release of _______
Definition
CD4
Lymphokines
Term
Can WBC cross the BBB?
Definition
yes
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