Term
| SLE is what type of hypersensitivity reaction? |
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Definition
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Term
| What meds are associated w/ drug-induced SLE? |
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Definition
| Procainamide, quinidine, INH, hydralazine |
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Term
| A positive anti-DS DNA test should make you think of what disease? |
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Definition
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Term
| Medication for SLE lesions? |
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Definition
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Term
| What disease state is CREST syndrome associated w/ and what does it consist of? |
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Definition
Scleroderma- limited cutaneous systemic sclerosis
Calcinosis
Raynaud's
Esophagitis
Sclerodactyly
Telangiectasias |
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Term
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Definition
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Term
| Diagnostic tests for Sjogren's? |
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Definition
Schirmer test (tears)
Anti-SSA (Ro) and Anti-SSB (La) |
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Term
| Tx options for Sjogren's? |
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Definition
Pilocarpine- stimulates lacrimation/salivation
Cevimeline- stimulates muscarinic cholinergic receptors |
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Term
| Some clinical manifestations of dermatomyositis? |
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Definition
Heliotrope rash on eyelid
Gottron's papules on knuckles
Shawl sign |
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Term
| In what disease state do we see negatively birefringent needle-shaped crystals on arthrocentesis? |
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Definition
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Term
| 1st line treatment in acute gout flare? |
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Definition
| NSAIDs (e.g. indomethacin/naprosyn); colchicine 2nd line |
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Term
| 1st line tx for chronic gout? |
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Definition
| Allopurinol (xanthine oxidase inhibitor) |
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Term
| Which presents with morning joint stiffness that improves throughout the day? OA or RA? |
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Definition
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Term
| Which diagnostic test is most specific for RA? |
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Definition
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Term
| Which medication is 1st line treatment for RA? What's it's drug class? |
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Definition
| Methotrexate; nonbiologic DMARD |
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Term
| Which disease is associated with the phrase "can't see, can't pee, can't climb a tree" (uveitis, urethritis, joint pain)? |
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Definition
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Term
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Definition
| Inflammation where ligament/tendon inserts onto bone |
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Term
| Pencil-in-cup deformity on XR indicates what disease? |
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Definition
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Term
| Dactylitis ("sausage fingers") is associated w/ what disease? |
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Definition
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Term
| "Bamboo spine" (squaring of vertebral bodies) on XR indicates what disease? |
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Definition
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Term
| What is the MC infection that triggers reactive arthritis? |
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Definition
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Term
| Patient is positive for Beta-2 glycoprotein and cardiolipin antibodies. What disease is most likely? |
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Definition
| Antiphospholipid syndrome |
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Term
| Patient is positive for glomerular basement membrane antibodies. What disease is most likely? |
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Definition
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