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Circulatory System
Chapter 38
128
Biology
Undergraduate 3
06/02/2006

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Term
two major functions of the circ system
Definition
acceptss oxygen, nutrients from respiratory and digestive systems and delivers them to cells. Also accepts carbon dioxide and wastes from cells and delivers them to respiratory and urinary systems for disposal.
Term
how does an open circ. system work?
Definition
heart pumps blood through vessel. Blood then moves into tissue spaces and mingles with fluid bathing cells. Blood reenters heart at openings in heart wall.
Term
closed circ. system?
Definition
heart pumps blood through a vessel which branches into smaller and smaller vessels. blood stays in vessels and interacts with cells through diffusion. blood re-enters heart at through returning vessels.
Term
in closed circ. system, volume of blood flowing through vessels always equal to...
Definition
hearts output
Term
velocity is highest in large or small diameter vessels?
Definition
large-diameter transport vessels
Term
flow velocity is slowest in..
Definition
capillary beds (small diameter blood vessels) due to higher surface area
Term
why do capillaries need to move fluids slower?
Definition
allows enough time for blood to exchange substances with interstitial fluids and cells
Term
during any interval there is the same volume of blood in (blank) as is the rest of the body:
Definition
capillaries
Term
two chanbered heart circ. system: oxygen poor blood is pumped to
Definition
the gills, where they pick up oxygen
Term
in a two chambered heart circ. system, oxygen rish blood flows:
Definition
directly from gills to the rest of the body.
Term
three chambered heart circ. syste pumps blood through two circuits that are...
Definition
partially seperate circuits
Term
in amphibians and reptiles, oxygen poor blood is pumped to..
Definition
the lungs
Term
in amphibians, oxygen rich blood flows from the lungs to the...
Definition
heart and mixes with oxygen poor blood before pumped to the rest of the body.
Term
four chambered hearts pump blood through how many cicuits? seperate or not?
Definition
two entirely seperate circuits
Term
in mammals oxygen poor blood is pumped to..
Definition
the lungs
Term
in mammals, oxygen rich blood is pumped...
Definition
to the heart, no mixing
Term
what type of tissue is blood?
Definition
connective
Term
what are the main functions of blood?
Definition
transports oxygen, nutrients, and hormones, carries carbon dioxide and wastes away from cells
Term
blood helps stabilize internal..
Definition
temperature, pH
Term
what percentage of body weight does blood make up?
Definition
6-8%
Term
what are the four components of blood?
Definition
plasma, red blood cells, white blood cells, platelets
Term
main function of plasma?
Definition
solvent, pH regulation, clotting, lipid, transport, dissolved gases, etc
Term
main function of red blood cells
Definition
oxygen and carbon dioxide transport
Term
main function of white blood cells
Definition
immune responses
Term
main funciton of platelets
Definition
clotting
Term
what type of blood cells are the most numerous?
Definition
red blood cells
Term
how many rbc in males?
Definition
5.4 mil per cubic cm
Term
how many rbc in females?
Definition
4.8 mil per cubic cm
Term
why are rbc red?
Definition
colored by red oxygen-binding pigment hemoglobin.
Term
what type of bc have no nucleus when mature?
Definition
red blood cells
Term
how long do rbc live?
Definition
only 120 days
Term
what happens to rbc after they die?
Definition
they are digested by phagocytes in the blood stream.
Term
where are rbc produced?
Definition
bone marrow (from stem cells within it)
Term
leukocytes come from
Definition
stem cells in bone marrow
Term
what are the five types of white blood celss
Definition
basophils, neutrophils, lymphocytes, macrophages, dendritic cells, Nk cells
Term
basophils
Definition
roles in inflammatory response to invasions and damags tissues
Term
neurohils
Definition
fast-acting phagocytes, roles in inflammatory response to invasions and damaged tissue
Term
lymphocytes
Definition
(t and b cells) respond to specific threats
Term
macrophages
Definition
call up ummune response
Term
dendrtic cells
Definition
call up immune response
Term
NK cells
Definition
destroy viral infested and cancerous cells.
Term
what are platelets?
Definition
membrane bound cell fragments
Term
where do platelets come from?
Definition
shed by megakaryocytes, which are deveoped from bone marrow.
Term
how long do platelets live?
Definition
about 9 days
Term
how do platelets initiate clotting?
Definition
they release a substance that initiates the clotting.
Term
why is blood seperated into types?
Definition
different types have different recognition proteins on their plasma membrane surface.
Term
type A has
Definition
one type of recognition marker
Term
Type B has
Definition
another type of recognition marker
Term
Type AB has
Definition
both recognition markers
Term
type O has
Definition
no recognition markers
Term
which is the universal recipient
Definition
AB
Term
Which is the universal donor?
Definition
type O
Term
Agglutination reaction occurs when
Definition
someone is given an incompatible blood type.
Term
what happens during an aglutination reaction?
Definition
antibodies in recipients blood are circulating throughout, if come into contact with blood with wrong recognition protein then act against them and cause them to clump together.
Term
Rh blood type
Definition
based on presence or absebce of Rh marker on red blood cells
Term
you are Rh+ if you
Definition
have the marker
Term
you are Rh- if you
Definition
do not have the marker
Term
what effect does Rh blood type have on preganent mothers?
Definition
if mother is Rh- and has previously carried Rh+ child then she may have made antibodies against the Rh marker. If she gets pregnant again with an Rh+ baby, her body might attack it.
Term
what factors have to be present in order for Rh blood type to have an effect on a pregnant mother?
Definition
the mother has to be Rh-, the father Rh+, and must have two children that are Rh+
Term
how can the Rh blood typing of mothers and babies be corrected?
Definition
anti-Rh gamma globulin
Term
how does anit-Rh gamma globulin work?
Definition
inactivates any Rh+ fetal blood cells before mom can develop antibodies against them.
Term
the top portion of the human heart is called the...
Definition
atrium
Term
the bottom portion of the human heart is called the
Definition
ventricle
Term
the right atria recieves blood from the...
Definition
body
Term
the left atria recieves blood from the...
Definition
lungs
Term
right ventricle pumps blood to the
Definition
lungs
Term
the left ventricle pumps blood to the
Definition
body
Term
each half of the heart pumps blood into a different circuit. They are the...
Definition
pulmonary circuit and the systemic circuit
Term
pulmonary circuit
Definition
oxygenates blood, blood flows from heart to lungs and returns to heart
Term
systemic circuit
Definition
circulates throughout body, blood flows from heart to body and returns to heart
Term
Blood flow through the pulmonary circuit
Definition
oxygen poor blood flows to the RA, oxygen porr blood pumped from the RV into pulmonary trunk, pulmonary trunk to pulmonary arteries, pukmonary arteries to capillary beds in left and right lungs, blood becomes oxygenated, oxygenated blood flows through pulmonary veins to LA of heart.
Term
blood flow through systemic circuit
Definition
oxygenated blood flows from LA to LV,then to aorta, then to thoracic organs or organs of the head (brain), deoxygenated blood flows back to RA
Term
hepatic portal system (HPS)
Definition
capillaries carry blood from intetstine to liver where blood is detoxified before being delivered to other partss of the body.
Term
right AV valve
Definition
connects right atrium to right ventricle
Term
right semilunar valve
Definition
connects right ventricle to pulmonary trunk
Term
pulmonary trunk
Definition
connects heart to pulmonary arteries, which take blood to the heart
Term
septum
Definition
partition between hearts two valves
Term
pulmonary veins
Definition
returns oxygenated blood to heart
Term
left AV valvle
Definition
connects left atrium and left ventricle
Term
left semilunar valve
Definition
connects left ventricle to aortic arch
Term
aortic arch
Definition
blood flows to body
Term
superior and inferior vena cava
Definition
deoxygenated blood returns to heart (right atrium)
Term
each time the heart beats, it goes through these two phases:
Definition
systole, diastole
Term
systole
Definition
contraction
Term
distole
Definition
relaxation
Term
when atria contracts (ventricles relax) and..
Definition
blood fills ventricles
Term
Lub
Definition
ventricles contracting, atria relaxing
Term
dub
Definition
atria contracting, ventricles relaxing
Term
in cardiac muscle, what facillitates action potentials?
Definition
gap junctions
Term
what percentage of cardiac muscles don't contract?
Definition
1%
Term
the muscles of the heart that don't contract act as a
Definition
cardiac conduction system
Term
how often does the cardian conduction system initiate waves of excitation
Definition
70 times per minute
Term
where do the waves (from the cardiac conduction system) start
Definition
sinoactrial node in right atrium
Term
the wave from the sinoatrial node spreads from the right atrium to
Definition
the left atrium, at which time both contract.
Term
after the atrium contracts, the wave travels from the sinoatrial node to the...
Definition
atrioventricula node
Term
The wave travels to down the septum via
Definition
purkinjie fibers, at which time both ventricles contract
Term
what acts as the cadiac pacemaker?
Definition
the SA node
Term
the four types of blood vessels
Definition
artery, arterioles, capillaries and venules, and veins
Term
arteries
Definition
main transporters of oxygenated blood
Term
arterioles
Definition
site of control over volume of blood flow, diameter is adjusted
Term
capillaries and venules
Definition
site of diffusion across thin walls
Term
veins
Definition
blood volume reservoirs and transporters of oxygen poor blood back to heart
Term
what is blood pressure?
Definition
fluid presure imparted to blood by heart contractions
Term
where is blood pressure highest and lowest?
Definition
highest in arteries, lowest in veins
Term
where is blood pressure highest and lowest?
Definition
highest in arteries, lowest in veins
Term
two types of blood pressure?
Definition
systolic pressure and diastolic pressure
Term
systolic pressure
Definition
peak pressure due to ventricular contraction
Term
diastolic pressure
Definition
is the lowest of cardiac cycle, reached when ventricles are relaxed
Term
capillary beds are the site of diffusion between...
Definition
blood and interstitial fluid (through diffusion and bulk flow)
Term
the capillary wall is a single sheet of
Definition
endothelial cells
Term
flow of blood through capillaries is
Definition
slow
Term
deoxygenated blood flows from capillaries into venules, then onto
Definition
veins
Term
are veins large or small diameter?
Definition
large
Term
what type of tissue do veins have in their wall that allows for constriction?
Definition
smooth muscle
Term
in veins, what prevents blood from flowing backwards?
Definition
valves
Term
purpose of the lymphatic system
Definition
helps body defefnd against injury and attack
Term
what is lymph fluid
Definition
some fluids are forced out of the smallest blood vessels and into interstitial fluid, this is lymph
Term
what happens to the lymph fluid, once it has been pushed out of the blood vessels?
Definition
vessels of the lymphatic system pick up this fluid, filter it, and return it to the circulatory system
Term
the lymphatic system consists of:
Definition
the lymph vascular system (drainage vessels) and the lymphoid orgains and lyohoid tissues
Term
the functions of the lymph vascular system
Definition
collect and deliver water and other solutes from interstitial fluid to circulartory sytem, collects lipids and delivers them to general circulation, delivers pathogens to lymph nodes
Term
what are the lymph organs and tissues?
Definition
lymph nodes, spleen, tonsils, thymus gland,
Term
lymph nodes
Definition
major lymph organs, strategically located along lymph vascular system, act as lymph filter
Term
what type of cells do lymph nodes carry?
Definition
lymphpcytes, that recognize and destroy invaders
Term
the largest lymph organ is the
Definition
spleen
Term
purpose of the spleen
Definition
filters pathogens and used up blood cells, antibody production
Term
tonsils
Definition
defense against bacteria and other foreign agents
Term
what organ has the largest role in immunity
Definition
thymus gland
Term
thymus gland
Definition
immature T lymphocytes differenciate into pathogen recognizing cells
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