Term
| Functions of the Circulatory System |
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Definition
Transportation
Regulation
Protection |
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Term
| what are the two systems of the circulatory system |
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Definition
| cardiovascular and lymphatic |
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Term
| how are the cardiovascular system and the lymphatic system linked? |
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Definition
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Term
| what is the cardiovascular system |
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Definition
| heart and network of blood vessels |
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Term
| what it the lymphatic system |
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Definition
cisterna chyli and the thoracic duct
and have other thin walled lymphatic vessels |
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Term
| what is the volume of blood? |
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Definition
apprx: 5 liters in an adult
55% is plama
45% formed elements |
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Term
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Definition
fluid that the blood elements are carried in
water ions
albumen (60-80%) osmotic pressure |
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Term
| organic molecules of plasma |
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Definition
proteins globulins (15-35%)
fibrinogen (4%)- clotting |
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Term
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Definition
fluid that results when you take fibrinogen out of the plasma
serum+fibrinogen=plasma |
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Term
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Definition
approx 5 mill/mm^3
120 day life span
concave disc
ach contain 280 mill hemoglobin molecules
heme is iron containing molecule which can be recycled and is carried to BM by transferrin |
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Term
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Definition
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Term
types of leukocyte
granulocytes |
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Definition
neutorphils (50-70%)
eosinophils
basophils-release histamine in allergy response |
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Term
type of leukocyte
agranulocytes |
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Definition
lympohcytes
monocytes-largest bean shaped- can leave blood and turn into macrophages that present things to you immune system |
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Term
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Definition
approx 200-500,000/mm^3
fragments of cells
thrombcytes- form bulk of a clot
secret serotonin in clot |
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Term
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Definition
ABO system
the more you have on the surface of your cell the more options you have of receiving blood |
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Term
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Definition
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Term
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Definition
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Term
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Definition
+ have Rh protein on the cell surface and is most common
- doesn't have Rh proteins on cell surface |
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Term
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Definition
antibodies against Rho (D)
so it is passive immunization |
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Term
| Three mechanisms of hemostasis |
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Definition
Vasconstriction
platelet plug
fibrin web |
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Term
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Definition
normally (within blood vessels) prostacyclin makes platelets repel one another
when endothelial lining is damaged collagen is exposed to the blood and becomes coated by Von willebrands factor
this causes platelets to stick to the collagen and degranulate releasing compounds that make other platelets sticky which causes vasoconstriction and clotting factors are activated |
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Term
| what does the platelet release reaction cause? |
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Definition
| the formation of a platelet plug |
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Term
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Definition
fibrin strengthens platelet plug
formed from fibrinogen in the plasma using different pathways due to action of clotting factors |
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Term
| intrinsic pathway to a platelet plug |
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Definition
activated by collagen exposure
doesn't need an activator protein
XII-12 activated |
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Term
| extrinsic pathway to a platelet plug |
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Definition
| activated by tissue throboplastin released by damaged tissue activating factor VII-7 |
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Term
| what do both the inartistic and extrinsic pathway lead to? |
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Definition
| the common pathway and fibrinogen formation |
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Term
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Definition
| Factor XII builds up and causes release of kallkrein which converts plasminogen to plasmin and that breaks down into fibrin split products (FSP) |
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Term
| three phases of the heart |
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Definition
systole- contraction- empty itself of blood
diastole- relaxation- to fill with blood
atrial systole-0.1 to 0.2 seconds-ventricular systole |
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Term
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Definition
the amount of blood in the ventricle at the end of its filling phase
80% due to end systolic volume plus passive flow
20% due to atrial contraction |
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Term
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Definition
the amount of blood pumped out of the ventricle during one contraction (one Beat)
equals approx 2/3 of the amount in the ventricle |
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Term
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Definition
the amount left in the ventricle at the end of its contraction phase
equals the 1/3 remaining amount in the ventricle |
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Term
| Isovolumetric contraction phase |
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Definition
occurs at the beginning of systole when pressure increases, causes the AV valves to close, but is not yet high enough to push open the semilunar valve
(volume hasn’t changed, starting to contract)
build up
(so the volume in the ventricle stays the same) |
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Term
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Definition
| the pressure in the ventricle is higher than in the aorta, so that the semilunar valve opens and blood flows out of the ventricle |
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Term
| isovolumetric relaxation phase |
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Definition
occurs at the beginning of diastole when pressure drops in the ventricle, allowing the semilunar valves to close but not low enough to allow the AV valves to open
relaxation |
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Term
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Definition
occurs when pressure in ventricle drops lower than the
pressure in the atrium, allowing the AV valves to open and blood to fill the ventricles |
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Term
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Definition
| contributes the final 20% to the end diastolic volume |
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Term
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Definition
| closure of the AV valves at the beginning of ventricular systole |
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Term
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Definition
| due to the closure of the semilunar valve at the beginning of ventricular diastole |
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Term
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Definition
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Term
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Definition
Defective/incompetent valves
stenosis of vessels
septal defects
patent ductus arteriousus-duct doesn't close after birth |
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Term
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Definition
depolarization of atria
triggers atrial contraction
end of diastole |
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Term
| normal QRS complex of an ECG |
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Definition
depolarization of ventricles
triggers ventricular contraction
isovolumetric contraction AV valves close
First heart sound
masks depolarization of the atria |
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Term
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Definition
depolarization of ventricles
triggers ventricular relaxation
isorelaxation pressure drops, blood back flow
seminars close
second heart sound |
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Term
| three functions of the lymph system |
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Definition
returning fluid to the cardiac system
picking up absorbed fats
distributes lymphocytes |
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Term
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Definition
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Term
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Definition
thoracic-legs and abdomen left side of the body to the subclavian
right duct- upper right stuff |
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Term
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Definition
nodules of developing lymphocytes
you can feel them
named for where they are in the body
they enlarge during and infection or cancer |
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Term
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Definition
tonsils
thymus
spleen- biggest and in the abdomen nothing to do with digestion has red and white pulp, acts as a storage area of red blood cells and storage of lymphocytes |
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