Term
| What are the most common symptoms of chronic viral hepatitis? |
|
Definition
1) fatigue
2) malaise
3) mild abdominal pain |
|
|
Term
| What lab tests are commonly seen with autoimmune hepatitis? |
|
Definition
1) ALT/AST elevation >400 IU/L
2) Bilirubin >3 mg/dl
3) increased gamma globulin levels |
|
|
Term
| Which autoimmune hepatitis is the most common in the US? |
|
Definition
| Type 1 autoimmune hepatitis |
|
|
Term
| What is characteristic of Type 1 autoimmune hepatitis? |
|
Definition
1) hypergammaglobulinemia
2) ANA (antinuclear antibody)
3) AMSA (anti-smooth muscle antibody) |
|
|
Term
| What is used as a diagnosis for chronic hepatitis B? |
|
Definition
| serological testing HbsAg positive |
|
|
Term
| What is the major determinant of chronicity in chronic hepatitis B? |
|
Definition
|
|
Term
| What risk is 200 times higher in those with HBV carriers? |
|
Definition
| development of hepatocellular carcinoma |
|
|
Term
| What are the two first line meds for chronic hepatitis B that inhibit viral DNA synthesis? |
|
Definition
1) entecavir
2) tenofovir
3) interferon |
|
|
Term
| How is chronic hepatitis C diagnosed? |
|
Definition
1) Elevated transaminase levels
2) Anti-HCV in serum |
|
|
Term
| What is the standard treatment for chronic hepatitis C? |
|
Definition
1) Pegulated interferon
2) ribavirin |
|
|
Term
| What is the most common indication for liver transplant? |
|
Definition
|
|
