Term
| How do fluoroquinolones work? |
|
Definition
| They disrupt cell division and DNA replication in the bacterial cell by inhibiting DNA gyrase and topoisomerase IV |
|
|
Term
| Which organism has become resistant enough to fluoroquinolones that they are no longer used to treat it? |
|
Definition
|
|
Term
| Oral fluoroquinolones are a viable alternative to which more invasive antibacterial therapy? |
|
Definition
| Hospitalization for parenteral antibiotics |
|
|
Term
| What is the major concern for patients taking fluoroquinolones? |
|
Definition
| Tendinitis and tendon rupture |
|
|
Term
| What must patients using fluoroquinolones do before sspending time outside? |
|
Definition
| Use protective clothing and sunscreen because fluoroquinolones pose a risk for phototoxicity |
|
|
Term
| Why should fluoroquinolones not be used in patients with myasthenia gravis? |
|
Definition
| It can exacerbate muscle weakness |
|
|
Term
| What substances can reduce absorption of fluoroquinolones? |
|
Definition
| Cationic substances including milk products (calcium), aluminum and magnesium containing antacids, iron and zinc salts, and sucralfate |
|
|
Term
| What organisms is Metronidazole useful against? |
|
Definition
| protozoa and infections caused by obligate anaerobic bacteria including Bacteroides fragilis and C. difficile |
|
|
Term
| If a patient must take antacids while on fluoroquinolones, when should they be taken? |
|
Definition
|
|
Term
| Which organisms is Metronidazole effective against? |
|
Definition
|
|
Term
| How is Bacitracin administered? |
|
Definition
|
|
