Term
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Definition
•The cell is the smallest structural and functional living unit
functions depend on individual and collective cell functions
activities of cells are dictated by their specific subcellular structures
•Continuity of life has a cellular basis
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Definition
(selectively permeable/ decides what can go in and what cannot)
•Bimolecular layer of lipids and proteins in a constantly changing fluid mosaic
•Separates (ICF) from (ECF)
(insterstial fluid/ between cells) |
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Term
fluid mosaic model
constantly changing |
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Definition
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Term
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Definition
forms the basic fabric of the membrane
75% phospholipids
5% glycolipid •
20% cholesterol |
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Term
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Definition
each lollipop shaped phosphate molecule has a
charged polar head that is |
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Definition
phospholipid molecule has a nonpolar tail w/ no chage made up of __________
line up @ the center of the membrane |
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Term
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Definition
•Plasma membrane—flexible outer boundary
•Cytoplasm—intracellular fluid containing organelles
•Nucleus—control center |
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Term
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Definition
a raft that sits on top of a cell w/ lil proteins sittin on it. foundation for cellular things to be sitting on
•~ 20% of the outer membrane surface
•Contain phospholipids, sphingolipids, and cholesterol
•May function as stable platforms for cell-signaling molecules |
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Definition
go all the way across the bilipid membrane. stick all the way through the membrane
•Firmly inserted into the membrane (most are transmembrane)
•Functions:
•Transport proteins (channels and carriers), enzymes, or receptors |
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Term
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Definition
•Loosely attached to integral proteins
•Functions:
•Enzymes, motor proteins, cell-to-cell links, provide support on intracellular surface, and form part of glycocalyx |
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Term
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Definition
(sugar covering)
part sugar part protein (tells self from nonself) (fits in receptor) |
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Term
membrane junctions
Tight junction |
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Definition
Impermeable junctions that encircle the cell
prevent molecules from passing through the intercellular space |
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Term
membrane junctions
Desmosome |
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Definition
strengthen hold between two cells
skin cells
: Anchoring junctions scattered along the sides of cells
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Term
membrane junctions
Gap junction |
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Definition
a nexus that allows chemical substances to pass between cells
channel for communicating between cells
Communicating junctions allow ions and small molecules to pass from one cell to the next for intercellular communication |
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Term
how do the phospholipid bilayer help seperate the IFC from the EFC? |
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Definition
phospholipid bilayer is made of lipids. the ifc and efc is made of water and the phospholipid bilayer help seperate water |
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Term
what is the importance of the glycocalyx |
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Definition
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Term
what kind of membrane juctrions would you find between heart and nerve cells |
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Definition
desmosomes and gap junctions |
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Term
what kind of junctions would be found between skin cells |
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Definition
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Term
what kind of junctions would u find between stomach cells |
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Definition
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Term
membrane transport (occurs only in living systems)
passive transport |
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Definition
•No cellular energy (ATP) required
•Substance moves down its concentration gradient
high to low
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Term
•What determines whether or not a substance can passively permeate a membrane? |
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Definition
1.Lipid solubility of substance
2.Channels of appropriate size
3.Carrier proteins |
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Term
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Definition
a type of passive transport in which transported substance either binds to a protien carrier in the membrane and is ferried across or moves through water filled protein |
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Term
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Definition
a type of passive transport in which molecules move from areas of higher concentration to lower concentration down or along its concentration gradient |
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Term
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Definition
the movement of solvent (water) across a selectively permeable membrane
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Term
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Definition
The measure of total concentration of solute particles |
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Term
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Definition
•solutions with same nonpenetrating solute concentration
no net water loss or gain, cell shape remains same |
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Term
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Definition
•solutions with greater nonpenetrating solute concentration than cytosol
•cells lose water and shrink/crenate
•change in cell volume disrupts cell function |
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Term
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Definition
•solutions with lesser nonpenetrating solute concentration than cytosol (ex-distilled water)
•cells take in water cells plump/burst/lyse
•change in cell volume disrupts cell function |
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Term
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Definition
•Requires carrier proteins (solute pumps)
•Moves solutes against a concentration gradient
requires ATP |
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Term
Sodium-potassium pump (Na+-K+ ATPase) |
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Definition
solute pumps
moves solutes most importantly ions uphill against its concentration gradient
•Located in all plasma membranes
•Maintains electrochemical gradients essential for functions of muscle and nerve tissues |
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Term
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Definition
vescular transport process that eject substances from the cells interior into the extracellular fluid
use of ATP
ex: •Hormone secretion
•Neurotransmitter release
•Mucus secretion |
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Term
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Definition
transport into cell
moves substances from the cells exterior to the cell interior |
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Term
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Definition
transport into, across, and then out of cell |
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Term
what is the energy source for all types of diffusion |
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Definition
is driven by the kinetic energy of the molecules |
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Term
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Definition
cell eating
use ATP
cell engulfs some large or solid material
•pseudopods engulf solids and bring them into cell’s interior |
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Term
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Definition
cell drinking
use ATP
•plasma membrane infolds, bringing extracellular fluid and solutes into interior of the cell
•Nutrient absorption in the small intestine |
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Term
how are cavolae n clathrin coated pits similar |
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Definition
capture specific molecules (flic acid, tetanus toxin) from the extra cellular fluid in coated vesicles and participates in some forms of transcytosis |
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Term
a cell placed in a hypotonic solution will |
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Definition
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Term
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Definition
the cell will stay the same
will try to reach dynamic equilibrium |
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Term
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Definition
Separation of oppositely charged particles (ions) across a membrane
(voltage across the membrane) |
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Term
membrane potential
electrochemical gradient
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Definition
the combined difference in concentration and charge influences the distrubution and direction of diffused ions |
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Term
cell adhesion molecules (CAM) |
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Definition
hold glycoproteins together
assist in movement of cells pass each other
assist in build up or break down of membrane junctions
embryonic and wound repair |
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Term
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Definition
huge diverse group of intergral proteins and glycoproteins that serve as binding sites.
receives contact and chemical sigmaling
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Term
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Definition
act as a relay or middleman to activate or inactivate a membrane bound enzyme or ion channel
linked receptors inside helping to convey a message |
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Term
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Definition
signaling chemicals that bind specifically to plasma membrane receptors
never enters/primary messenger |
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Term
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Definition
one or 2 intracellular chemical signals that are generated and connect plasma membrane events to the internal metabolic machinery of the cell
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Term
resting membrane potential |
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Definition
diffusion of ions, mainly the diffusion of K+ from the cell throughh leakage channels establishes the
positive on the outside and negative on the inside |
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Term
what are the relative inside and outside charges of a cell @ rest? which ions are responsible? |
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Definition
the inside is negative relative to its outside
inside -K+
outside +NA+ |
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Term
ligand gated channels are opened or closed in response to the binding of a chemical messenger such as a neurotransmitter
a voltage gated channel open and close depending on membrane potential |
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Definition
what is the difference between a voltage gated channel and a lingand gated channel? |
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Term
why do protein based hormones use second messengers while lipid based hormones do not? |
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Definition
because anything w/ a charge needs a secondary
messenger system
anything w/out a charge can go straight in |
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Term
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Definition
•Located between plasma membrane and nucleus
consist of 3 parts: cytosol, organelles and inclusions |
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Term
membranous cytoplasmic organelles |
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Definition
mitochondria
peroxisomes
lysosomes
endoplasmic reticulum
golgi apparatus |
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Term
nonmemebranus cytoplasmic organells |
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Definition
•Cytoskeleton
•Centrioles
•Ribosomes |
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Term
“What is the equation for cellular respiration?” |
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Definition
C6H12O6 + 6O2 → 6H2O + 6CO2 + 30(net) ATP
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Term
What are the three steps of cellular respiration?” |
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Definition
Glycolysis, krebs cycle and Electron transport system |
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Term
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Definition
all mitochondria comes from the egg (mother cell)
•Double-membrane structure with shelflike cristae
•Provide most of cell’s ATP via aerobic cellular respiration
•Contain their own DNA and RNA
space is called matrix |
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Term
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Definition
•Granules containing protein and rRNA
protein synthesis |
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Term
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Definition
synthesize soluble proteins
float freely in the cytoplasm
imported into the mitchondria as well as some other organelles |
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Term
Membrane-bound ribosomes (on rough ER) |
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Definition
synthesize proteins to be incorporated into membranes or exported from the cell |
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Term
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Definition
•External surface studded with ribosomes
•Manufactures all secreted proteins
•Synthesizes membrane integral proteins and phospholipids |
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Term
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Definition
•Tubules arranged in a looping network
•Enzyme (integral protein) functions:
•In the liver—lipid and cholesterol metabolism, breakdown of glycogen, and, along with kidneys, detoxification of drugs, pesticides, and carcinogens
•Synthesis of steroid-based hormones
•In intestinal cells—absorption, synthesis, and transport of fats
•In skeletal and cardiac muscle—storage and release of calcium |
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Term
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Definition
•Stacked and flattened membranous sacs
•Modifies, concentrates, and packages proteins and lipids
Transport vessels from ER fuse with convex cis face of |
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Term
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Definition
contains proteins destained for export pinch off from the transface which migrates tot the plasma membrane and discharge the contents from the cell |
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Term
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Definition
•Spherical membranous bags containing digestive enzymes (acid hydrolases)
•Digest ingested bacteria, viruses, and toxins
•Degrade nonfunctional organelles
•Break down and release glycogen
•Break down bone to release Ca2+
•Destroy cells in injured or nonuseful tissue (autolysis) |
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Term
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Definition
•Membranous sacs containing powerful oxidases and catalases
•Detoxify harmful or toxic substances like hydrogen peroxide H2O2-> H2O + O ( free radical)
•Neutralize dangerous free radicals (highly reactive chemicals with unpaired electrons) |
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Term
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Definition
acts as cells bones muscles and ligaments by supporting cellular structure and providing the machinery to provide various cell movements
•Elaborate series of rods throughout cytosol
•Microtubules
•Microfilaments
•Intermediate filaments |
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Term
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Definition
•: (“Center body”) near nucleus
•Generates microtubules; organizes mitotic spindle
•Contains centrioles: |
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Term
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Definition
Small tube formed by microtubules (nine sets of triplets
generates microtubles and organizes the mitotic spindle in cell division |
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Term
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Definition
•Whiplike, motile extensions on surfaces of certain cells
Contain microtubules and motor molecules |
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Term
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Definition
hair like projections that moves tuff across a cell like mucus in the trachea. air flowing in and out of the trachea is passive |
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Term
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Definition
propel whole cells (tail of sperm) |
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Term
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Definition
protein complexes that function in motility
(movement of organelles and contraction)
powered by ATP |
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Term
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Definition
•Fingerlike extensions of plasma membrane
•Increase surface area for absorption (so u can digest food)
•Core of actin filaments for stiffening |
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Term
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Definition
control center of the cell
•Genetic library with blueprints for nearly all cellular proteins
•Responds to signals and dictates kinds and amounts of proteins to be synthesized
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Term
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Definition
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Term
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Definition
•Threadlike strands of DNA (30%), histone proteins (60%), and RNA (10%)
•Arranged in fundamental units called nucleosomes
•Condense into barlike bodies called chromosomes when the cell starts to divide |
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Term
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Definition
process that occurs b4 cell division. it ensures all daughter cells have identical genes
•End result: two DNA molecules formed from the original
•This process is called semiconservative replication
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Term
“Which cells are associated with G0?” |
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Definition
heart cells, brain cells and nerve cells |
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Term
•Mitotic (M) phase of the cell cycle |
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Definition
•Essential for body growth and tissue repair
•Does not occur in most mature cells of nervous tissue, skeletal muscle, and cardiac muscle |
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Term
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Definition
division of cytoplasm by cleavage furrow |
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Term
what is the 1st step of protein synthesis |
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Definition
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Term
where does transcription take place |
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Definition
it takes place in the nucleus |
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Term
what is the 2nd step of protein synthesis |
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Definition
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Term
where does translation take place |
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Definition
it takes place outside of nucleus on the ribosomes |
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Term
what is a protease
ex: proteasomes |
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Definition
enzyme that breaks down proteins |
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Term
protein degredation
ubiquitin proteins |
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Definition
used to marked damaged proteins to be degraded |
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Term
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Definition
•Development of specific and distinctive features in cells
helps determine what type of cell its gonna be |
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Term
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Definition
•Elimination of excess, injured, or aged cells occurs through programmed rapid cell death _____________) followed by phagocytosis |
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Term
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Definition
abnormal cell structure; cancer cells different from parent cell
abnormalities in cell structure and loss of differentation |
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Term
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Definition
change in cell shape, size, or arrangement due to chronic irritation or inflammation |
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Term
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Definition
increase in size of tissue due to increase in cell number |
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Term
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Definition
increase in size of an organ or tissue due to increase in cell size |
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Term
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Definition
(strings of nucleotides on the ends of chromosomes) may determine the number of times a cell can divide |
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Term
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Definition
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Term
what is the importance of ubiquitin in the life of a cell |
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Definition
because it helps get rid of damaged or unneeded proteins |
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Term
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Definition
must end w/ an OH to be a
NaOH, Mg(OH),
except: NH3, HCO3
C2 OH and C2H3OH arent ____ causes start w/ carbon
grabs protons H+ |
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Term
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Definition
if it stars w/ an H+
releases H+ to counter the OH- |
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Term
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Definition
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Term
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Definition
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Term
respitory, cardiovascular and urinary system |
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Definition
what 3 body systems as part of their function to keep up acid base balance |
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Term
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Definition
H2CO3 ----> H+ + HCO3-
starts w/ carbonic acid ends w/ a base |
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Term
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Definition
HCI + NaOH ------------> NaCl + H-OH |
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Term
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Definition
disassociate quickly so release many H+ or OH that will hurt you |
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Term
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Definition
potential and chemical energy
the only other kind of energy is positional energy |
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Term
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Definition
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Term
because the telemeres decide how many times a cell can divide |
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Definition
how are telemeres related to the condition "progeria" and dolly the cloned sheep? |
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Term
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Definition
lipids w/ attached sugar groups |
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Term
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Definition
involves the transfer of info from a DNAs base sequence to the complementary base sequence of an mRNA molecule |
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Term
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Definition
the language of nucleic acids (base sequence) is translated into the language of proteins (amino acid sequence) |
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Term
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Definition
non functional organelle proteins are degraded by lysosomes |
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Term
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Definition
turns genes of specific cells on or off |
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Term
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Definition
high to low non polar lipids- soluble diffuse straight through |
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Term
cell environment interactions |
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Definition
involves glycoproteins and proteins of glycocalyx |
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Term
what are some functions membrane proteins perform |
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Definition
transport, enzymatic activity, receptors for signal transduction, intercellular adhesion, cell to cell recognition |
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Term
Substance (Vesicular) Trafficking |
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Definition
Transport from one area of cell or organelle to another. |
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Term
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Definition
segments that comes from sagging strand in DNA replication |
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Term
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Definition
splices together short segments of discontinuous strand |
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Term
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Definition
turns genes of specific cells on or off |
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Term
chemical -> endocytosis, exocytosis, and active transport |
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Definition
ATP is what kind of energy |
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Term
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Definition
•Leakage channels
•Always open
•Gated channels
•Controlled by chemical or electrical signals |
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Term
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Definition
untwists the double helix and exposes complementary chains |
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Term
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Definition
•The Y-shaped site of replication |
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Term
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Definition
Each nucleotide strand serves as a template for building a new |
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Term
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Definition
•only works in one direction
•Continuous leading strand is synthesized |
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Term
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Definition
splices together short segments of discontinuous strand |
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Term
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Definition
•Discontinuous lagging strand is synthesized in segments |
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Term
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Definition
•Critical volume of cell when area of membrane is inadequate for exchange
Chemicals (e.g., growth factors, hormones, cyclins, and cyclin-dependent kinases (Cdks |
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Term
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Definition
•Contact inhibition
Growth-inhibiting factors produced by repressor genes |
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Term
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Definition
segments of DNA carrying instructions for a polypeptide chain |
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Term
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Definition
•of nucleotide bases form the genetic library
•Each specifies coding for an amino acid |
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Term
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Definition
– carries the genetic information from DNA in the nucleus to the ribosomes in the cytoplasm |
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Term
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Definition
bound to amino acids base pair with the codons of mRNA at the ribosome to begin the process of protein synthesis |
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Term
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Definition
– a structural component of ribosomes |
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Term
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Definition
•Enzyme that oversees synthesis of mRNA
•Unwinds DNA template
•Adds complementary RNA nucleotides on DNA template and joins them together
•Stops when it reaches termination signal
•mRNA pulls off the DNA template, is further processed by enzymes, and enters cytosol |
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Term
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Definition
With the help of transcription factors, RNA polymerase binds to the promoter, pries apart the two DNA strands, and initiates mRNA synthesis at the start point on the template strand. |
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Term
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Definition
As the RNA polymerase moves along the template strand, elongating the mRNA transcript one base at a time, it unwinds the DNA double helix before it and rewinds the double helix behind it. |
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Term
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Definition
mRNA synthesis ends when the termination signal is reached. RNA polymerase and the completed mRNA transcript are released. |
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Term
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Definition
•DNA triplets are transcribed into mRNA codons by |
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Term
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Definition
•Codons base pair with tRNA anticodons at the |
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Term
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Definition
Misfolded, damaged or unneeded proteins are marked for destruction |
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Term
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Definition
The tagged proteins are then degraded by |
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Definition
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Term
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Definition
only proteins are disolved by |
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Term
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Definition
if a cell is dissolving their own functional organelle |
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Term
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Definition
when u want to synthesize something by removing water |
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Term
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Definition
when u want to break something down you want to add water |
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Term
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Definition
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Term
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Definition
biggest part of interphase where stuff grows and becomes what its gonna become |
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