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Cholinergic Agonists
N/A
9
Pharmacology
Graduate
10/28/2011

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Term
List 6 Cholinergic Agonists with Muscarinic Action
Definition
1. Acetylcholine chloride
2. Methacholine chloride
3. Carbachol chloride
4. Bethanechol chloride
5. Pilocarpine
6. Cevimeline (Evoxac)
Term
List 2 Cholinergic Agonists with Muscatinic and Nicotinic Action
Definition
1. Actylcholine chloride
2. Carbachol chloride
Term
List 2 Cholinergic Agonists with Muscarinic Action that are susceptible to Cholinesterase
Definition
1. Acetylcholine chloride
2. Methacholine chloride
Term
What is the effect of a cholinergic agonist on the eye?
Definition
*constrict iris sphincter and ciliary muscle (accomodation for near vision)
*facilitates drainage of aqueous humor
Term
What is the effect of a cholinergic agonist on the cardiovascular system?
Definition
*lowered pulse rate
*lowered peripheral vascular resistance
Term
what is the direct effect of a cholinergic agonist on the heart? Why is there a decreased heart rate?
Definition
*increased K+ effulx from SA, AV nodes & atrial muscle = hyperpolarization
*less Ca2+ influx
Term
What is the effect of a cholinergic agonist on the respiratory system?
Definition
*contraction of smooth muscle of bronchi
*increased bronchial secretion
Term
What is the effect of a cholinergic agonist on the GI?
Definition
*increased secretory & motor activity
*increased peristalsis, relaxed sphincters
Term
What is the effect of a cholinergic agonist on the GU?
Definition
*increased contraction of the bladder wall
*decreased contraction of teh sphincter muscles
*end result is urination
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