Shared Flashcard Set

Details

Cholesterol
Exam 1
24
Pharmacology
Graduate
12/10/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Ezetimibe (Zetia)
Definition
Cholesterol absorption inhibitor
Term
Cholestyramine (Questran)
Definition
Bile Acid Binding Resin
Term
Colestipol (Colestid)
Definition
Bile Acid Binding Resin
Term
Colesevelam (Welchol)
Definition
Bile Acid Binding Resin
Term
Lovastatin
Definition
HMG-COA Reductase Inhibitor
Term
Pravastatin
Definition
HMG-COA Reductase Inhibitor
Term
Simvastatin
Definition
HMG-COA Reductase Inhibitor
Term
Atorvastatin
Definition
HMG-COA Reductase Inhibitor
Term
Rosuvastatin (Crestor)
Definition
HMG-COA Reductase Inhibitor
Term
Gemfibrozil (Lopid)
Definition
Fibric Acid Analogue (Fibrates)
Term
Fenofibrate (Tricor)
Definition
Fibric Acid Analogue (Fibrates)
Term
Effect of ezetimibe
Definition
↓LDL HDL
Term
Effect of HMG-COA Reductase Inhibitors
Definition

LDL ↑HDL

increases LDL receptors in liver: less circulating LDL

Term
Effect of Niacin on Cholesterol
Definition
↓VLDL ↓LDL HDL
Term
Effect of fibrates
Definition
VLDL ↓LDL ↑HDL
Term
Effect of Lovaza
Definition

↓VLDL (no change in LDL)

(safe when combo with statins)

Term
Effect of bile acid bindingresins
Definition
↓LDL
Term
Decreased absorption of dietary & Biliary Cholesterol across brush border
Definition
Ezetimibe
Term

Exchange Cl for Bile acid

can't be absorbed

Definition
Bile acid binding resin
Term
Bloating & Constipation
Definition
Bile acid resins
Term
Inhibit intracellular lipolysis
Definition
Niacin
Term

Peptic ulcers

gastric acid secretion

Definition
Niacin
Term

Lipoproten Lipase

PPAR

Definition
Fibrate
Term

effa

oxidation

Definition
omega 3
Supporting users have an ad free experience!